ID   ELMOD_DICDI             Reviewed;        1267 AA.
AC   Q54UP9;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Ankyrin repeat and ELMO domain-containing protein D;
GN   Name=elmoD; ORFNames=DDB_G0280943;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
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DR   EMBL; AAFI02000039; EAL67013.1; -; Genomic_DNA.
DR   RefSeq; XP_640972.1; XM_635880.1.
DR   AlphaFoldDB; Q54UP9; -.
DR   SMR; Q54UP9; -.
DR   STRING; 44689.DDB0233923; -.
DR   PaxDb; Q54UP9; -.
DR   EnsemblProtists; EAL67013; EAL67013; DDB_G0280943.
DR   GeneID; 8622776; -.
DR   KEGG; ddi:DDB_G0280943; -.
DR   dictyBase; DDB_G0280943; elmoD.
DR   eggNOG; KOG2998; Eukaryota.
DR   HOGENOM; CLU_264313_0_0_1; -.
DR   InParanoid; Q54UP9; -.
DR   OMA; TAFRKQI; -.
DR   PRO; PR:Q54UP9; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0007015; P:actin filament organization; IBA:GO_Central.
DR   GO; GO:0048870; P:cell motility; IBA:GO_Central.
DR   Gene3D; 1.25.40.20; -; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR024574; ELMO_ARM.
DR   InterPro; IPR006816; ELMO_dom.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF11841; DUF3361; 1.
DR   Pfam; PF04727; ELMO_CED12; 1.
DR   SMART; SM00248; ANK; 4.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 1.
DR   PROSITE; PS51335; ELMO; 1.
PE   4: Predicted;
KW   ANK repeat; Reference proteome; Repeat.
FT   CHAIN           1..1267
FT                   /note="Ankyrin repeat and ELMO domain-containing protein D"
FT                   /id="PRO_0000333281"
FT   DOMAIN          307..466
FT                   /note="ELMO"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00664"
FT   REPEAT          655..685
FT                   /note="ANK 1"
FT   REPEAT          689..718
FT                   /note="ANK 2"
FT   REPEAT          767..796
FT                   /note="ANK 3"
FT   REPEAT          801..830
FT                   /note="ANK 4"
FT   REGION          486..598
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          854..908
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          924..1040
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1057..1082
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1103..1215
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        486..500
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        501..598
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        855..884
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        891..908
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1103..1210
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1267 AA;  140089 MW;  B954DE06DAEA5E54 CRC64;
     MTHTIRVLIK YQNSMIDHFI IKGVKLSTQI DMFCQIFKIQ EDPIKYSLLV EDLGVYLTDD
     AIFHENSTYI NINNKVLELQ LGTSYQVSSV LKTMSSCKDL KKSLVLLKSH LTKNFCAEFI
     KKGGLEHLQA IIKSESASAN TLSVAFGILE ILSVYPDFSW DYISQPVIDK VVSNFGYINV
     NPSLKLGIKL ATDRKGYTML QNSIDKTFDT TTGDNCVYSK IVNGNLSSTD INTQTSTLNL
     INNMVSFSQS PIEFLKNLES YNISSTLKSQ LSATDTAFRK QIYLFQCHKI QGLIMDSKTP
     YNKDEPSHQR LLETLWSTLF PNQVFQRSHE NWQIIGFQNK DPSSDFRGMG LAGLKHLIYL
     AQNHKDMFMN PLINRQPEAN YYPYATSGIQ VTSFLVECVK PINISANHSD VIGQIYPILF
     ESENALNEIY CVLMEIFGIV WKDWNATYMI FQKVFQFVSG LASEVLPKCK CVVDFKSLII
     EKLENKKKEK KSEKRGSVST RHSKQFGSNG NINSTTTTTT TTTTTTTPIS TTGSGSSNSL
     NGNTSNNNNN NNISMSYSSN NGSTLSGLGN NHSSNNNNNN NNNNNNNNNN HILNNNHLYV
     NNTNSNSSGN NMISCSPSGS SISGSGSISI HNSQSMNSKT FIEDIDIDAC TVSPDGNSPL
     HSAIMNSMTL DCITNGININ LFLNTTNNQG LTPLNLACSI SPYLIIDFFL QQDTDPFIPA
     KNGEYPFHNF CSRKWTFNEF TRGCSLFLAK SNHHQYHDIV NQTNHVTLET PLSTAIQSGN
     EDSVGHLLTL CPNINNYFNS SGQNALHIAI SKRNLHIITC LIQNGADPSI PNEITKETCE
     DICASDPEIM IILNPTKLSR STSSTSSSTS RIHDESNNNG SIKKNPIPLP KRPQITNNNS
     IQYSNSTSSN SLINNNNFNN LLSTSINNSY NNNNNNNNNN NNNNNNNNNN NNNNNNNNPN
     NNNNNNNNNN PNNNSNNNNN NNNNNNNNNN NSTLNVNNNN NSNNNHQYVN SPYNSNKSSI
     SSPNHNNTPS TSPGITSPIF RSATPLKQTM SVGLMHSPTQ ESPQVISTPT SPPYLSNNNG
     AERVYGRSGS GFFNNINGMF NQENLTKNSG NNNNNNSSSS GGSSSSNSNG INNNNNNNIN
     NNNNNNNNNN NNNNNNGSIG NSGNYNHMNN INIGSHHSNH HSNHNGPINN GNYPNYRGNN
     ITTSPVGVTV TPPKDQKKAD SVVNVRRLLN ESLCLVDLIC SGPEKQKENV KKLNEALKSC
     LKNVKNF