ID   ELOA1_ASHGO             Reviewed;         332 AA.
AC   Q75E67;
DT   13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Elongin-A;
GN   Name=ELA1; OrderedLocusNames=ABL197C;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- SUBUNIT: Forms a complex with SKP1-like protein ELC1. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ELA1 family. {ECO:0000305}.
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DR   EMBL; AE016815; AAS50574.1; -; Genomic_DNA.
DR   RefSeq; NP_982750.1; NM_208103.1.
DR   AlphaFoldDB; Q75E67; -.
DR   STRING; 33169.AAS50574; -.
DR   EnsemblFungi; AAS50574; AAS50574; AGOS_ABL197C.
DR   GeneID; 4618829; -.
DR   KEGG; ago:AGOS_ABL197C; -.
DR   eggNOG; KOG2821; Eukaryota.
DR   HOGENOM; CLU_062289_0_0_1; -.
DR   InParanoid; Q75E67; -.
DR   OMA; RRTTFFN; -.
DR   Proteomes; UP000000591; Chromosome II.
DR   GO; GO:0070449; C:elongin complex; IEA:InterPro.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; IEA:InterPro.
DR   InterPro; IPR001810; F-box_dom.
DR   InterPro; IPR010684; RNA_pol_II_trans_fac_SIII_A.
DR   Pfam; PF06881; Elongin_A; 1.
DR   PROSITE; PS50181; FBOX; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..332
FT                   /note="Elongin-A"
FT                   /id="PRO_0000239642"
FT   DOMAIN          24..68
FT                   /note="F-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
FT   REGION          228..332
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        234..266
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        297..314
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   332 AA;  37873 MW;  A973EA8B8AC0E2B3 CRC64;
     METGHPPSLQ ELCVVVLMRH HAQLEDIGHM PYALVRRVLL KMSAEQLLRL ERASPALLLE
     DEEAWQQLLK KDFPTNVHEV WVARKKDVYE YYLESVRELG PQVLEDRALV RSLLRAAVCK
     DPVLFKYRVP SRQLYQRYVH EDARRQELSA ARLRQSTLQL QQEKQKTRIT QLEDPLYLER
     ELNAGRQRAA PQRSSIYLKS FKELRQRQAH FRSGGYDPTQ RRIVRVQTPS AQPAASLHPP
     PQSAPMAGSP QKPAPPEQPL AASPTPEAPG PLAQRRRPSA RRQPPPASPA KRRSALFSSP
     ALSTLLPQQD DTDSDTGGRP PKKPRVYIHT PR