ELOF1_ARATH
ID ELOF1_ARATH Reviewed; 120 AA.
AC Q8LEF3; Q9FNL9;
DT 25-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Transcription elongation factor 1 homolog;
GN OrderedLocusNames=At5g46030; ORFNames=MCL19.8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9405937; DOI=10.1093/dnares/4.4.291;
RA Kotani H., Nakamura Y., Sato S., Kaneko T., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. II. Sequence
RT features of the regions of 1,044,062 bp covered by thirteen physically
RT assigned P1 clones.";
RL DNA Res. 4:291-300(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transcription elongation factor implicated in the maintenance
CC of proper chromatin structure in actively transcribed regions.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ELOF1 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB08248.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB006698; BAB08248.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED95330.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM68284.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM68285.1; -; Genomic_DNA.
DR EMBL; BT002010; AAN72021.1; -; mRNA.
DR EMBL; BT006515; AAP21323.1; -; mRNA.
DR EMBL; AY085452; AAM62678.1; -; mRNA.
DR RefSeq; NP_001330049.1; NM_001344655.1.
DR RefSeq; NP_001330050.1; NM_001344654.1.
DR RefSeq; NP_568654.1; NM_123971.3.
DR AlphaFoldDB; Q8LEF3; -.
DR SMR; Q8LEF3; -.
DR BioGRID; 19893; 1.
DR IntAct; Q8LEF3; 1.
DR STRING; 3702.AT5G46030.1; -.
DR PaxDb; Q8LEF3; -.
DR PRIDE; Q8LEF3; -.
DR ProteomicsDB; 220659; -.
DR EnsemblPlants; AT5G46030.1; AT5G46030.1; AT5G46030.
DR EnsemblPlants; AT5G46030.2; AT5G46030.2; AT5G46030.
DR EnsemblPlants; AT5G46030.3; AT5G46030.3; AT5G46030.
DR GeneID; 834644; -.
DR Gramene; AT5G46030.1; AT5G46030.1; AT5G46030.
DR Gramene; AT5G46030.2; AT5G46030.2; AT5G46030.
DR Gramene; AT5G46030.3; AT5G46030.3; AT5G46030.
DR KEGG; ath:AT5G46030; -.
DR Araport; AT5G46030; -.
DR TAIR; locus:2161418; AT5G46030.
DR eggNOG; KOG3214; Eukaryota.
DR HOGENOM; CLU_105983_1_0_1; -.
DR InParanoid; Q8LEF3; -.
DR OMA; VGRIICR; -.
DR OrthoDB; 1630132at2759; -.
DR PhylomeDB; Q8LEF3; -.
DR PRO; PR:Q8LEF3; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q8LEF3; baseline and differential.
DR Genevisible; Q8LEF3; AT.
DR GO; GO:0008023; C:transcription elongation factor complex; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000993; F:RNA polymerase II complex binding; IBA:GO_Central.
DR GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; IBA:GO_Central.
DR Gene3D; 2.20.25.190; -; 1.
DR InterPro; IPR007808; Elf1.
DR InterPro; IPR038567; T_Elf1_sf.
DR PANTHER; PTHR20934; PTHR20934; 1.
DR Pfam; PF05129; Elf1; 1.
PE 2: Evidence at transcript level;
KW Metal-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..120
FT /note="Transcription elongation factor 1 homolog"
FT /id="PRO_0000120946"
FT REGION 84..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..109
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 25
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:P60003"
FT BINDING 28
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:P60003"
FT BINDING 49
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:P60003"
FT BINDING 52
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:P60003"
SQ SEQUENCE 120 AA; 13885 MW; DDAF1CD76316BA1F CRC64;
MGKRKSRAKP APTKRMDKLD TIFSCPFCNH GSSVECIIDM KHLIGKAACR ICEESFSTTI
TALTEAIDIY SEWIDECERV NTAEDDVVQE EEEEVEEEEE EEEEEDDEDD HVSVKRKYNF
