ELOF1_CAEEL
ID ELOF1_CAEEL Reviewed; 84 AA.
AC Q9XVZ8;
DT 25-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Transcription elongation factor 1 homolog;
GN ORFNames=Y54G11A.11;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: Transcription elongation factor implicated in the maintenance
CC of proper chromatin structure in actively transcribed regions.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ELOF1 family. {ECO:0000305}.
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DR EMBL; AL034488; CAA22454.1; -; Genomic_DNA.
DR PIR; T27174; T27174.
DR RefSeq; NP_496983.1; NM_064582.6.
DR AlphaFoldDB; Q9XVZ8; -.
DR SMR; Q9XVZ8; -.
DR BioGRID; 40371; 1.
DR DIP; DIP-27150N; -.
DR STRING; 6239.Y54G11A.11.2; -.
DR EPD; Q9XVZ8; -.
DR PaxDb; Q9XVZ8; -.
DR PeptideAtlas; Q9XVZ8; -.
DR EnsemblMetazoa; Y54G11A.11.1; Y54G11A.11.1; WBGene00013219.
DR EnsemblMetazoa; Y54G11A.11.2; Y54G11A.11.2; WBGene00013219.
DR GeneID; 175090; -.
DR KEGG; cel:CELE_Y54G11A.11; -.
DR UCSC; Y54G11A.11.1; c. elegans.
DR CTD; 175090; -.
DR WormBase; Y54G11A.11; CE22483; WBGene00013219; -.
DR eggNOG; KOG3214; Eukaryota.
DR GeneTree; ENSGT00390000000053; -.
DR HOGENOM; CLU_105983_2_0_1; -.
DR InParanoid; Q9XVZ8; -.
DR OMA; ISCRVCS; -.
DR OrthoDB; 1630132at2759; -.
DR PhylomeDB; Q9XVZ8; -.
DR PRO; PR:Q9XVZ8; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00013219; Expressed in embryo and 4 other tissues.
DR GO; GO:0005730; C:nucleolus; HDA:WormBase.
DR GO; GO:0008023; C:transcription elongation factor complex; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000993; F:RNA polymerase II complex binding; IBA:GO_Central.
DR GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; IBA:GO_Central.
DR Gene3D; 2.20.25.190; -; 1.
DR InterPro; IPR007808; Elf1.
DR InterPro; IPR038567; T_Elf1_sf.
DR PANTHER; PTHR20934; PTHR20934; 1.
DR Pfam; PF05129; Elf1; 1.
PE 3: Inferred from homology;
KW Metal-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..84
FT /note="Transcription elongation factor 1 homolog"
FT /id="PRO_0000120943"
FT BINDING 26
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:P60003"
FT BINDING 29
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:P60003"
FT BINDING 50
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:P60003"
FT BINDING 53
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:P60003"
SQ SEQUENCE 84 AA; 9667 MW; E996ECFC218D227C CRC64;
MGKRKSKRKA PTKAKAVMPL DTQFNCPFCN HERVCEVKMD REKNVGYISC RVCSEDFQTN
INYLSEPIDV YSDWVDACEQ ANNA
