ID   ELOF1_DICDI             Reviewed;          80 AA.
AC   Q54KR5;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Transcription elongation factor 1 homolog;
GN   Name=elof1; ORFNames=DDB_G0287203;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Transcription elongation factor implicated in the maintenance
CC       of proper chromatin structure in actively transcribed regions.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ELOF1 family. {ECO:0000305}.
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DR   EMBL; AAFI02000098; EAL63876.1; -; Genomic_DNA.
DR   RefSeq; XP_637365.1; XM_632273.1.
DR   AlphaFoldDB; Q54KR5; -.
DR   SMR; Q54KR5; -.
DR   STRING; 44689.DDB0266346; -.
DR   PaxDb; Q54KR5; -.
DR   EnsemblProtists; EAL63876; EAL63876; DDB_G0287203.
DR   GeneID; 8625987; -.
DR   KEGG; ddi:DDB_G0287203; -.
DR   dictyBase; DDB_G0287203; elof1.
DR   eggNOG; KOG3214; Eukaryota.
DR   HOGENOM; CLU_105983_2_0_1; -.
DR   InParanoid; Q54KR5; -.
DR   OMA; ISCRVCS; -.
DR   PhylomeDB; Q54KR5; -.
DR   PRO; PR:Q54KR5; -.
DR   Proteomes; UP000002195; Chromosome 4.
DR   GO; GO:0005634; C:nucleus; ISS:dictyBase.
DR   GO; GO:0008023; C:transcription elongation factor complex; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000993; F:RNA polymerase II complex binding; ISS:dictyBase.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; ISS:dictyBase.
DR   Gene3D; 2.20.25.190; -; 1.
DR   InterPro; IPR007808; Elf1.
DR   InterPro; IPR038567; T_Elf1_sf.
DR   PANTHER; PTHR20934; PTHR20934; 1.
DR   Pfam; PF05129; Elf1; 1.
PE   3: Inferred from homology;
KW   Metal-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..80
FT                   /note="Transcription elongation factor 1 homolog"
FT                   /id="PRO_0000327211"
FT   BINDING         24
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250|UniProtKB:P60003"
FT   BINDING         27
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250|UniProtKB:P60003"
FT   BINDING         48
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250|UniProtKB:P60003"
FT   BINDING         51
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250|UniProtKB:P60003"
SQ   SEQUENCE   80 AA;  8993 MW;  E8E39204399A1147 CRC64;
     MGKRKSSKPP PKKVVQKLPK HFDCLFCAHS QSVDCILDRE LGKGVAKCRV CNASYETPIH
     ELSDAIDVYS DWIDACESIR