ID   ELOF1_ENCCU             Reviewed;          80 AA.
AC   Q8STS7;
DT   25-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   25-NOV-2002, sequence version 2.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Transcription elongation factor 1 homolog;
GN   OrderedLocusNames=ECU09_0850;
OS   Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite).
OC   Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae;
OC   Encephalitozoon.
OX   NCBI_TaxID=284813;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GB-M1;
RX   PubMed=11719806; DOI=10.1038/35106579;
RA   Katinka M.D., Duprat S., Cornillot E., Metenier G., Thomarat F.,
RA   Prensier G., Barbe V., Peyretaillade E., Brottier P., Wincker P.,
RA   Delbac F., El Alaoui H., Peyret P., Saurin W., Gouy M., Weissenbach J.,
RA   Vivares C.P.;
RT   "Genome sequence and gene compaction of the eukaryote parasite
RT   Encephalitozoon cuniculi.";
RL   Nature 414:450-453(2001).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=GB-M1;
RX   PubMed=20003517; DOI=10.1186/1471-2164-10-607;
RA   Peyretaillade E., Goncalves O., Terrat S., Dugat-Bony E., Wincker P.,
RA   Cornman R.S., Evans J.D., Delbac F., Peyret P.;
RT   "Identification of transcriptional signals in Encephalitozoon cuniculi
RT   widespread among Microsporidia phylum: support for accurate structural
RT   genome annotation.";
RL   BMC Genomics 10:607-607(2009).
CC   -!- FUNCTION: Transcription elongation factor implicated in the maintenance
CC       of proper chromatin structure in actively transcribed regions.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ELOF1 family. {ECO:0000305}.
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DR   EMBL; AL590451; CAD27058.2; -; Genomic_DNA.
DR   RefSeq; XP_955639.1; XM_950546.1.
DR   AlphaFoldDB; Q8STS7; -.
DR   SMR; Q8STS7; -.
DR   STRING; 284813.Q8STS7; -.
DR   PRIDE; Q8STS7; -.
DR   GeneID; 860424; -.
DR   KEGG; ecu:ECU09_0850; -.
DR   VEuPathDB; MicrosporidiaDB:ECU09_0850; -.
DR   HOGENOM; CLU_105983_2_0_1; -.
DR   InParanoid; Q8STS7; -.
DR   OrthoDB; 1630132at2759; -.
DR   Proteomes; UP000000819; Chromosome IX.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 2.20.25.190; -; 1.
DR   InterPro; IPR007808; Elf1.
DR   InterPro; IPR038567; T_Elf1_sf.
DR   PANTHER; PTHR20934; PTHR20934; 1.
DR   Pfam; PF05129; Elf1; 1.
PE   3: Inferred from homology;
KW   Metal-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..80
FT                   /note="Transcription elongation factor 1 homolog"
FT                   /id="PRO_0000120948"
FT   BINDING         25
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250|UniProtKB:P60003"
FT   BINDING         28
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250|UniProtKB:P60003"
FT   BINDING         49
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250|UniProtKB:P60003"
FT   BINDING         52
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250|UniProtKB:P60003"
SQ   SEQUENCE   80 AA;  9213 MW;  835D34ADDE0F14DA CRC64;
     MGRRRVKRRI NIPKRQSRLE KRFNCPVCNH ENVVQCTVKK TLMKGFANCS VCEASFACDA
     NKLTTGIDVY SAWVDECCKR