ID   EM13_ECHMU              Reviewed;         426 AA.
AC   Q07840;
DT   25-MAR-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Antigen EM13;
GN   Name=EM13;
OS   Echinococcus multilocularis (Fox tapeworm).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC   Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus.
OX   NCBI_TaxID=6211;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8479454; DOI=10.1016/0166-6851(93)90052-y;
RA   Frosch P., Geier C., Muller A., Frosch M.;
RT   "Molecular cloning of an echinococcal microtrichal antigen immunoreactive
RT   in Echinococcus multilocularis disease.";
RL   Mol. Biochem. Parasitol. 58:301-310(1993).
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DR   EMBL; M96565; AAA29054.1; -; mRNA.
DR   EMBL; M84807; AAA29055.1; -; mRNA.
DR   EMBL; M95052; AAA29061.1; -; mRNA.
DR   PIR; A48580; A48580.
DR   AlphaFoldDB; Q07840; -.
DR   SMR; Q07840; -.
DR   eggNOG; KOG2856; Eukaryota.
DR   Gene3D; 1.20.1270.60; -; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR031160; F_BAR.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   Pfam; PF00018; SH3_1; 1.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF103657; SSF103657; 1.
DR   SUPFAM; SSF50044; SSF50044; 1.
DR   PROSITE; PS51741; F_BAR; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; SH3 domain.
FT   CHAIN           1..426
FT                   /note="Antigen EM13"
FT                   /id="PRO_0000086965"
FT   DOMAIN          1..240
FT                   /note="F-BAR"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01077"
FT   DOMAIN          371..426
FT                   /note="SH3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00192"
FT   REGION          280..315
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          350..369
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        281..315
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   426 AA;  47535 MW;  A4B5ED41EC6DACC1 CRC64;
     MIQERADIEK AYASNLRKFA ARLEMFLRTG VEYGTATNIL SGLAKEAEDN AELHSNIAAG
     LINPVQLGIK NWQRENFHKS SISTSIKEVK NFDSEFENAQ KTWYKHYKNV NRCKKEYFHA
     CKTVRSLQVQ VQNAKNEPFG TPEQLRKIED KLRKGIMEEE KTRKAYEEAL SSLSDVTPRY
     IEDMTQVFNK AQAFERERII YFKEQALQMQ EVLDISAKPN LSQIFVGLRE TVAKVDADAD
     LKKWSLAYGV DMAPNFPVFQ EYSPEMSALG KKGRSALADG SSGGVTLTSL KTITSPDRGG
     PIPGTTDSGS NISTSPVHTT AYGSNSYDHG SEGATPSDYT SSVNGAAAAI SKEKQRVEDT
     PPYPDFVDDG RPGVPIRALY DYVGVEADEL SFNSGDLFEK LEDEDEQGWC KGRKDGRVGL
     YPRQLR