ID   EM55_CHICK              Reviewed;         468 AA.
AC   Q5ZJ00;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=55 kDa erythrocyte membrane protein;
DE            Short=p55;
DE   AltName: Full=Membrane protein, palmitoylated 1;
GN   Name=MPP1; Synonyms=EMP55; ORFNames=RCJMB04_22d9;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: May play a role in the regulation of neutrophil polarization.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane; Peripheral membrane protein. Cell
CC       projection, stereocilium {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MAGUK family. {ECO:0000305}.
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DR   EMBL; AJ720634; CAG32293.1; -; mRNA.
DR   RefSeq; NP_001007918.1; NM_001007917.2.
DR   AlphaFoldDB; Q5ZJ00; -.
DR   SMR; Q5ZJ00; -.
DR   STRING; 9031.ENSGALP00000008114; -.
DR   PaxDb; Q5ZJ00; -.
DR   Ensembl; ENSGALT00000008128; ENSGALP00000008114; ENSGALG00000005071.
DR   GeneID; 422197; -.
DR   KEGG; gga:422197; -.
DR   CTD; 4354; -.
DR   VEuPathDB; HostDB:geneid_422197; -.
DR   eggNOG; KOG0609; Eukaryota.
DR   GeneTree; ENSGT00940000158744; -.
DR   HOGENOM; CLU_001715_5_1_1; -.
DR   InParanoid; Q5ZJ00; -.
DR   OMA; QAPNAMT; -.
DR   OrthoDB; 95102at2759; -.
DR   PhylomeDB; Q5ZJ00; -.
DR   TreeFam; TF314263; -.
DR   PRO; PR:Q5ZJ00; -.
DR   Proteomes; UP000000539; Chromosome 4.
DR   Bgee; ENSGALG00000005071; Expressed in colon and 12 other tissues.
DR   ExpressionAtlas; Q5ZJ00; baseline and differential.
DR   GO; GO:0005911; C:cell-cell junction; IBA:GO_Central.
DR   GO; GO:0034451; C:centriolar satellite; IEA:Ensembl.
DR   GO; GO:0030863; C:cortical cytoskeleton; IEA:Ensembl.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell.
DR   GO; GO:0005102; F:signaling receptor binding; IBA:GO_Central.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0090022; P:regulation of neutrophil chemotaxis; IEA:Ensembl.
DR   CDD; cd12080; SH3_MPP1; 1.
DR   Gene3D; 2.30.42.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR008145; GK/Ca_channel_bsu.
DR   InterPro; IPR008144; Guanylate_kin-like_dom.
DR   InterPro; IPR020590; Guanylate_kinase_CS.
DR   InterPro; IPR035475; MPP1_SH3.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   Pfam; PF00625; Guanylate_kin; 1.
DR   Pfam; PF00595; PDZ; 1.
DR   Pfam; PF00018; SH3_1; 1.
DR   SMART; SM00072; GuKc; 1.
DR   SMART; SM00228; PDZ; 1.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF50044; SSF50044; 1.
DR   SUPFAM; SSF50156; SSF50156; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00856; GUANYLATE_KINASE_1; 1.
DR   PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR   PROSITE; PS50106; PDZ; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   SH3 domain; Transferase.
FT   CHAIN           1..468
FT                   /note="55 kDa erythrocyte membrane protein"
FT                   /id="PRO_0000347220"
FT   DOMAIN          73..154
FT                   /note="PDZ"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00143"
FT   DOMAIN          160..230
FT                   /note="SH3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00192"
FT   DOMAIN          284..453
FT                   /note="Guanylate kinase-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00100"
SQ   SEQUENCE   468 AA;  52520 MW;  C228FB9FFFA44DE8 CRC64;
     MTLKSGRGGG GGSGSMRTAL SDLYLEHLLQ NRAKPEAIAQ APNAMTEDIY TNGSATLGSP
     SHSNGREVRK IRLVQFEKVT EEPMGITLKL NDKQSCMVAR IFHGGMIHRQ GSLHVGDEII
     EINGQSVSNH SVDQLQKMLK ETQGMVSIKV IPNQQSRLPA LQMFMRAQFD YDPKKDNLIP
     CKEAGLKFQT GDVIQIINKD DSNWWQGRVE GSGTESAGLI PSPELQEWRV ASVTQSSQSE
     AQSCSPFGKK KKYKDKYLAK HSSIFDQLDV VSYEEVVRLP AFKRKTLVLI GASGVGRSHI
     KNALLSNNPE KFMYPPPYTT RPQKKNEVDG KDYYFVSTEE MTRDISANEF LEFGSYQGNM
     FGTKFETVHK IHQQDKVAIL DIEPQTLKIV RTAELSPFIV FIAPTDKAEE SEALQQLRKD
     SESIRSRYAH YFDLSIVNNG VEESLKLLEE AFEQACSSPQ WVPVSWVY