ID   EMI1_YEAST              Reviewed;         187 AA.
AC   Q04406; D6VTD3;
DT   16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 123.
DE   RecName: Full=Early meiotic induction protein 1;
GN   Name=EMI1; OrderedLocusNames=YDR512C; ORFNames=D9719.18;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169867;
RA   Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G.,
RA   Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C.,
RA   Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F.,
RA   Delaveau T., del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M.,
RA   Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T.,
RA   Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C.,
RA   Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S.,
RA   Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N., Paulin L.,
RA   Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M., Prydz H.,
RA   Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L., Rieger M.,
RA   Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M., Scharfe M.,
RA   Schmidt E.R., Schneider C., Scholler P., Schwarz S., Soler-Mira A.,
RA   Urrestarazu L.A., Verhasselt P., Vissers S., Voet M., Volckaert G.,
RA   Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S., Harris D.E.,
RA   Bowman S., Brown D., Churcher C.M., Connor R., Dedman K., Gentles S.,
RA   Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D., Niblett D.,
RA   Odell C., Oliver K., Rajandream M.A., Richards C., Shore L., Walsh S.V.,
RA   Barrell B.G., Dietrich F.S., Mulligan J.T., Allen E., Araujo R., Aviles E.,
RA   Berno A., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M.,
RA   Hunicke-Smith S., Hyman R.W., Komp C., Lashkari D., Lew H., Lin D.,
RA   Mosedale D., Nakahara K., Namath A., Oefner P., Oh C., Petel F.X.,
RA   Roberts D., Schramm S., Schroeder M., Shogren T., Shroff N., Winant A.,
RA   Yelton M.A., Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R.,
RA   Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S., Greco T.,
RA   Hallsworth K., Hawkins J., Hillier L.W., Jier M., Johnson D., Johnston L.,
RA   Kirsten J., Kucaba T., Langston Y., Latreille P., Le T., Mardis E.,
RA   Menezes S., Miller N., Nhan M., Pauley A., Peluso D., Rifkin L., Riles L.,
RA   Taich A., Trevaskis E., Vignati D., Wilcox L., Wohldman P., Vaudin M.,
RA   Wilson R., Waterston R., Albermann K., Hani J., Heumann K., Kleine K.,
RA   Mewes H.-W., Zollner A., Zaccaria P.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.";
RL   Nature 387:75-78(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   FUNCTION.
RX   PubMed=12586695; DOI=10.1093/genetics/163.1.47;
RA   Enyenihi A.H., Saunders W.S.;
RT   "Large-scale functional genomic analysis of sporulation and meiosis in
RT   Saccharomyces cerevisiae.";
RL   Genetics 163:47-54(2003).
CC   -!- FUNCTION: Involved in sporulation. Required for the full activation of
CC       the early meiotic inducer IME1. {ECO:0000269|PubMed:12586695}.
CC   -!- SIMILARITY: Belongs to the EMI1 family. {ECO:0000305}.
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DR   EMBL; U33057; AAB64954.1; -; Genomic_DNA.
DR   EMBL; BK006938; DAA12343.1; -; Genomic_DNA.
DR   PIR; S69569; S69569.
DR   RefSeq; NP_010800.3; NM_001180820.3.
DR   AlphaFoldDB; Q04406; -.
DR   BioGRID; 32564; 252.
DR   DIP; DIP-5374N; -.
DR   IntAct; Q04406; 1.
DR   STRING; 4932.YDR512C; -.
DR   iPTMnet; Q04406; -.
DR   MaxQB; Q04406; -.
DR   PaxDb; Q04406; -.
DR   PRIDE; Q04406; -.
DR   EnsemblFungi; YDR512C_mRNA; YDR512C; YDR512C.
DR   GeneID; 852125; -.
DR   KEGG; sce:YDR512C; -.
DR   SGD; S000002920; EMI1.
DR   VEuPathDB; FungiDB:YDR512C; -.
DR   eggNOG; ENOG502S4MN; Eukaryota.
DR   HOGENOM; CLU_1556487_0_0_1; -.
DR   InParanoid; Q04406; -.
DR   BioCyc; YEAST:G3O-30032-MON; -.
DR   PRO; PR:Q04406; -.
DR   Proteomes; UP000002311; Chromosome IV.
DR   RNAct; Q04406; protein.
DR   GO; GO:0030437; P:ascospore formation; HMP:SGD.
DR   GO; GO:0007005; P:mitochondrion organization; IMP:SGD.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; HMP:SGD.
DR   InterPro; IPR021475; DUF3128.
DR   PANTHER; PTHR28052; PTHR28052; 1.
DR   Pfam; PF11326; DUF3128; 1.
PE   3: Inferred from homology;
KW   Meiosis; Reference proteome; Sporulation.
FT   CHAIN           1..187
FT                   /note="Early meiotic induction protein 1"
FT                   /id="PRO_0000223039"
SQ   SEQUENCE   187 AA;  21071 MW;  F77E1830413A4D59 CRC64;
     MIITIKFESK EKLVSMKQYI TVVGVSVNQE GTFSWRPGTF YMKIHEESAA GPFAKGAEIS
     DLSNSSAIGC GISINQEGGD GSIRVKESSL RKKQERMSTK YPTTMSCREA FDQLTSCYSI
     GGQFRSYYRY GDFTSCDKQV SKFKFCIIHG NDPVKVQEWY KDQVSNNKAL ENTSGVIWQE
     RETTANK