EMP1_HUMAN
ID EMP1_HUMAN Reviewed; 157 AA.
AC P54849; B2R5N1; B4DRR1; O00681; Q13481; Q13834;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 15-JUL-1998, sequence version 3.
DT 03-AUG-2022, entry version 167.
DE RecName: Full=Epithelial membrane protein 1;
DE Short=EMP-1;
DE AltName: Full=CL-20;
DE AltName: Full=Protein B4B;
DE AltName: Full=Tumor-associated membrane protein;
GN Name=EMP1; Synonyms=B4B, TMP;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
RC TISSUE=Fetal kidney;
RX PubMed=8996089; DOI=10.1016/s0378-1119(96)00475-1;
RA Ben-Porath I., Benvenisty N.;
RT "Characterization of a tumor-associated gene, a member of a novel family of
RT genes encoding membrane glycoproteins.";
RL Gene 183:69-75(1996).
RN [2]
RP SEQUENCE REVISION TO 83.
RA Ben-Porath I., Benvenisty N.;
RL Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
RX PubMed=9126480; DOI=10.1006/geno.1997.4524;
RA Chen Y., Medvedev A., Ruzanov P., Marvin K.W., Jetten A.M.;
RT "cDNA cloning, genomic structure, and chromosome mapping of the human
RT epithelial membrane protein CL-20 gene (EMP1), a member of the PMP22
RT family.";
RL Genomics 41:40-48(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
RC TISSUE=Blood;
RX PubMed=8683158;
RA Ruegg C.L., Wu H., Fagnoni F.F., Engleman E.G., Laus R.;
RT "B4B, a novel growth-arrest gene, is expressed by a subset of
RT progenitor/pre-B lymphocytes negative for cytoplasmic mu-chain.";
RL J. Immunol. 157:72-80(1996).
RN [5]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
RX PubMed=9066625;
RA Schiemann S., Rueckels M., Engelholm L.H., Schwirzke M., Bruenner N.,
RA Weidle U.H.;
RT "Differential gene expression in human mammary carcinoma cells:
RT identification of a new member of a receptor family.";
RL Anticancer Res. 17:13-20(1997).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC TISSUE=Tongue;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16541075; DOI=10.1038/nature04569;
RA Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y.,
RA Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C.,
RA Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C.,
RA Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R.,
RA Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E.,
RA Song X.-Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y.,
RA Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G.,
RA Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H.,
RA Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S.,
RA Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M.,
RA Nguyen B.-V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J.H.,
RA Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q.,
RA Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V.,
RA Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E.,
RA Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K.,
RA Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D.,
RA Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R.,
RA David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E.,
RA D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N.,
RA Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N.,
RA Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R.,
RA Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S.,
RA LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H.,
RA Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P.,
RA Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G.,
RA Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E.,
RA Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S.,
RA Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O.,
RA Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J.,
RA Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A.,
RA Perrin W., Pickens A., Primus E.L., Pu L.-L., Puazo M., Quiles M.M.,
RA Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I.,
RA Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A.,
RA Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y.,
RA Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A.,
RA Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F.,
RA Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L.,
RA Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G.,
RA Gibbs R.A.;
RT "The finished DNA sequence of human chromosome 12.";
RL Nature 440:346-351(2006).
RN [8]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [9]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Liver;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC P54849; P16157-17: ANK1; NbExp=3; IntAct=EBI-4319440, EBI-941819;
CC P54849; Q68DC2: ANKS6; NbExp=3; IntAct=EBI-4319440, EBI-7054139;
CC P54849; Q9BQE5: APOL2; NbExp=3; IntAct=EBI-4319440, EBI-4290634;
CC P54849; Q13520: AQP6; NbExp=3; IntAct=EBI-4319440, EBI-13059134;
CC P54849; Q3SXY8: ARL13B; NbExp=3; IntAct=EBI-4319440, EBI-11343438;
CC P54849; Q15041: ARL6IP1; NbExp=3; IntAct=EBI-4319440, EBI-714543;
CC P54849; P07307-3: ASGR2; NbExp=3; IntAct=EBI-4319440, EBI-12808270;
CC P54849; Q99437: ATP6V0B; NbExp=3; IntAct=EBI-4319440, EBI-3904417;
CC P54849; O15342: ATP6V0E1; NbExp=3; IntAct=EBI-4319440, EBI-12935759;
CC P54849; Q8WVV5: BTN2A2; NbExp=3; IntAct=EBI-4319440, EBI-8648738;
CC P54849; P51681: CCR5; NbExp=3; IntAct=EBI-4319440, EBI-489374;
CC P54849; P11049: CD37; NbExp=3; IntAct=EBI-4319440, EBI-6139068;
CC P54849; P09693: CD3G; NbExp=3; IntAct=EBI-4319440, EBI-3862428;
CC P54849; P19397: CD53; NbExp=3; IntAct=EBI-4319440, EBI-6657396;
CC P54849; P11912: CD79A; NbExp=3; IntAct=EBI-4319440, EBI-7797864;
CC P54849; Q8NHQ1: CEP70; NbExp=3; IntAct=EBI-4319440, EBI-739624;
CC P54849; O95484: CLDN9; NbExp=3; IntAct=EBI-4319440, EBI-18341636;
CC P54849; Q9Y5Q5: CORIN; NbExp=3; IntAct=EBI-4319440, EBI-17876114;
CC P54849; P25025: CXCR2; NbExp=3; IntAct=EBI-4319440, EBI-2835281;
CC P54849; Q15125: EBP; NbExp=3; IntAct=EBI-4319440, EBI-3915253;
CC P54849; Q92838: EDA; NbExp=3; IntAct=EBI-4319440, EBI-529425;
CC P54849; Q08426: EHHADH; NbExp=3; IntAct=EBI-4319440, EBI-2339219;
CC P54849; Q9Y282: ERGIC3; NbExp=3; IntAct=EBI-4319440, EBI-781551;
CC P54849; O15552: FFAR2; NbExp=3; IntAct=EBI-4319440, EBI-2833872;
CC P54849; Q96F15: GIMAP5; NbExp=3; IntAct=EBI-4319440, EBI-6166686;
CC P54849; O15529: GPR42; NbExp=3; IntAct=EBI-4319440, EBI-18076404;
CC P54849; Q9NZD1: GPRC5D; NbExp=3; IntAct=EBI-4319440, EBI-13067820;
CC P54849; P28335: HTR2C; NbExp=3; IntAct=EBI-4319440, EBI-994141;
CC P54849; Q6UXK2: ISLR2; NbExp=3; IntAct=EBI-4319440, EBI-1266923;
CC P54849; Q9HDC5: JPH1; NbExp=3; IntAct=EBI-4319440, EBI-465137;
CC P54849; P26715: KLRC1; NbExp=3; IntAct=EBI-4319440, EBI-9018187;
CC P54849; Q86VI4: LAPTM4B; NbExp=3; IntAct=EBI-4319440, EBI-3267258;
CC P54849; O95214: LEPROTL1; NbExp=3; IntAct=EBI-4319440, EBI-750776;
CC P54849; Q8TAF8: LHFPL5; NbExp=3; IntAct=EBI-4319440, EBI-2820517;
CC P54849; P43657: LPAR6; NbExp=3; IntAct=EBI-4319440, EBI-2876949;
CC P54849; Q96PB8: LRRC3B; NbExp=3; IntAct=EBI-4319440, EBI-17775622;
CC P54849; Q8N112: LSMEM2; NbExp=6; IntAct=EBI-4319440, EBI-10264855;
CC P54849; P21145: MAL; NbExp=3; IntAct=EBI-4319440, EBI-3932027;
CC P54849; Q13021: MALL; NbExp=3; IntAct=EBI-4319440, EBI-750078;
CC P54849; Q9GZW8: MS4A7; NbExp=3; IntAct=EBI-4319440, EBI-721391;
CC P54849; P35372-10: OPRM1; NbExp=3; IntAct=EBI-4319440, EBI-12807478;
CC P54849; Q96CS7: PLEKHB2; NbExp=3; IntAct=EBI-4319440, EBI-373552;
CC P54849; Q01453: PMP22; NbExp=3; IntAct=EBI-4319440, EBI-2845982;
CC P54849; Q9UI14: RABAC1; NbExp=3; IntAct=EBI-4319440, EBI-712367;
CC P54849; Q9NS64: RPRM; NbExp=3; IntAct=EBI-4319440, EBI-1052363;
CC P54849; A2A2V5: SERTM1; NbExp=3; IntAct=EBI-4319440, EBI-17284533;
CC P54849; Q9BZL3: SMIM3; NbExp=6; IntAct=EBI-4319440, EBI-741850;
CC P54849; Q9HBV2: SPACA1; NbExp=3; IntAct=EBI-4319440, EBI-17498703;
CC P54849; P27105: STOM; NbExp=3; IntAct=EBI-4319440, EBI-1211440;
CC P54849; Q8N205: SYNE4; NbExp=3; IntAct=EBI-4319440, EBI-7131783;
CC P54849; Q0VAB0: TBXA2R; NbExp=3; IntAct=EBI-4319440, EBI-18271435;
CC P54849; Q9Y6I9: TEX264; NbExp=3; IntAct=EBI-4319440, EBI-10329860;
CC P54849; Q96MV1: TLCD4; NbExp=3; IntAct=EBI-4319440, EBI-12947623;
CC P54849; B3SHH9: TMEM114; NbExp=3; IntAct=EBI-4319440, EBI-19132172;
CC P54849; Q9NX00: TMEM160; NbExp=3; IntAct=EBI-4319440, EBI-2514588;
CC P54849; A2RU14: TMEM218; NbExp=3; IntAct=EBI-4319440, EBI-10173151;
CC P54849; Q8WW34-2: TMEM239; NbExp=3; IntAct=EBI-4319440, EBI-11528917;
CC P54849; E9PQX1: TMEM262; NbExp=3; IntAct=EBI-4319440, EBI-17180389;
CC P54849; Q9P0T7: TMEM9; NbExp=3; IntAct=EBI-4319440, EBI-723976;
CC P54849; Q5TGU0: TSPO2; NbExp=3; IntAct=EBI-4319440, EBI-12195249;
CC -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=P54849-1; Sequence=Displayed;
CC Name=2;
CC IsoId=P54849-2; Sequence=VSP_056984;
CC -!- SIMILARITY: Belongs to the PMP-22/EMP/MP20 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; U43916; AAC51783.1; -; mRNA.
DR EMBL; U77085; AAC51207.1; -; mRNA.
DR EMBL; Z50751; CAA90627.1; -; mRNA.
DR EMBL; Y07909; CAA69217.1; -; mRNA.
DR EMBL; AK299388; BAG61373.1; -; mRNA.
DR EMBL; AK312246; BAG35178.1; -; mRNA.
DR EMBL; AC022276; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC079628; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH471094; EAW96304.1; -; Genomic_DNA.
DR EMBL; BC047300; AAH47300.1; -; mRNA.
DR CCDS; CCDS8660.1; -. [P54849-1]
DR PIR; G02355; G02355.
DR RefSeq; NP_001414.1; NM_001423.2. [P54849-1]
DR AlphaFoldDB; P54849; -.
DR SMR; P54849; -.
DR BioGRID; 108327; 62.
DR IntAct; P54849; 61.
DR STRING; 9606.ENSP00000256951; -.
DR GlyGen; P54849; 2 sites.
DR PhosphoSitePlus; P54849; -.
DR BioMuta; EMP1; -.
DR DMDM; 3041684; -.
DR MassIVE; P54849; -.
DR PaxDb; P54849; -.
DR PeptideAtlas; P54849; -.
DR PRIDE; P54849; -.
DR TopDownProteomics; P54849-1; -. [P54849-1]
DR Antibodypedia; 23604; 116 antibodies from 19 providers.
DR DNASU; 2012; -.
DR Ensembl; ENST00000256951.10; ENSP00000256951.5; ENSG00000134531.10. [P54849-1]
DR Ensembl; ENST00000396301.7; ENSP00000379595.3; ENSG00000134531.10. [P54849-2]
DR GeneID; 2012; -.
DR KEGG; hsa:2012; -.
DR MANE-Select; ENST00000256951.10; ENSP00000256951.5; NM_001423.3; NP_001414.1.
DR UCSC; uc001rbr.4; human. [P54849-1]
DR CTD; 2012; -.
DR DisGeNET; 2012; -.
DR GeneCards; EMP1; -.
DR HGNC; HGNC:3333; EMP1.
DR HPA; ENSG00000134531; Tissue enhanced (esophagus, vagina).
DR MIM; 602333; gene.
DR neXtProt; NX_P54849; -.
DR OpenTargets; ENSG00000134531; -.
DR PharmGKB; PA27770; -.
DR VEuPathDB; HostDB:ENSG00000134531; -.
DR eggNOG; ENOG502S028; Eukaryota.
DR GeneTree; ENSGT00950000182696; -.
DR HOGENOM; CLU_138632_0_1_1; -.
DR InParanoid; P54849; -.
DR OMA; KSVQAFM; -.
DR OrthoDB; 1218356at2759; -.
DR PhylomeDB; P54849; -.
DR TreeFam; TF330414; -.
DR PathwayCommons; P54849; -.
DR SignaLink; P54849; -.
DR BioGRID-ORCS; 2012; 15 hits in 1071 CRISPR screens.
DR ChiTaRS; EMP1; human.
DR GeneWiki; EMP1; -.
DR GenomeRNAi; 2012; -.
DR Pharos; P54849; Tbio.
DR PRO; PR:P54849; -.
DR Proteomes; UP000005640; Chromosome 12.
DR RNAct; P54849; protein.
DR Bgee; ENSG00000134531; Expressed in lower esophagus mucosa and 197 other tissues.
DR ExpressionAtlas; P54849; baseline and differential.
DR Genevisible; P54849; HS.
DR GO; GO:0016021; C:integral component of membrane; TAS:ProtInc.
DR GO; GO:0005886; C:plasma membrane; IDA:UniProtKB.
DR GO; GO:0032060; P:bleb assembly; IDA:UniProtKB.
DR GO; GO:0008219; P:cell death; IDA:UniProtKB.
DR GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR InterPro; IPR003932; EMP_1.
DR InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR InterPro; IPR004032; PMP22_EMP_MP20.
DR PANTHER; PTHR10671:SF6; PTHR10671:SF6; 1.
DR Pfam; PF00822; PMP22_Claudin; 1.
DR PRINTS; PR01453; EPMEMFAMILY.
DR PRINTS; PR01454; EPMEMPROT1.
DR PROSITE; PS01221; PMP22_1; 1.
DR PROSITE; PS01222; PMP22_2; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Glycoprotein; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..157
FT /note="Epithelial membrane protein 1"
FT /id="PRO_0000164653"
FT TRANSMEM 1..21
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 67..87
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 95..115
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 134..154
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CARBOHYD 43
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 46
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT VAR_SEQ 106..157
FT /note="WLCILVGVSIYTSHYANRDGTQYHHGYSYILGWICFCFSFIIGVLYLVLRKK
FT -> FIMRIVMERSITTAIPTSWAGSASASASSSAFSIWS (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:14702039"
FT /id="VSP_056984"
FT VARIANT 57
FT /note="S -> N (in dbSNP:rs34412222)"
FT /id="VAR_050608"
SQ SEQUENCE 157 AA; 17563 MW; B470B4ADC5C16821 CRC64;
MLVLLAGIFV VHIATVIMLF VSTIANVWLV SNTVDASVGL WKNCTNISCS DSLSYASEDA
LKTVQAFMIL SIIFCVIALL VFVFQLFTME KGNRFFLSGA TTLVCWLCIL VGVSIYTSHY
ANRDGTQYHH GYSYILGWIC FCFSFIIGVL YLVLRKK
