ID   EMP_STAAS               Reviewed;         340 AA.
AC   Q6GB43;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Extracellular matrix protein-binding protein emp;
DE   Flags: Precursor;
GN   Name=emp; OrderedLocusNames=SAS0754;
OS   Staphylococcus aureus (strain MSSA476).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=282459;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MSSA476;
RX   PubMed=15213324; DOI=10.1073/pnas.0402521101;
RA   Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J.,
RA   Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A.,
RA   Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C.,
RA   Clark L., Corton C., Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z.,
RA   Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N.,
RA   Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A.,
RA   Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M.,
RA   Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J.;
RT   "Complete genomes of two clinical Staphylococcus aureus strains: evidence
RT   for the rapid evolution of virulence and drug resistance.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004).
CC   -!- FUNCTION: Adhesin that binds to the host cell extracellular matrix
CC       proteins fibronectin, fibrinogen, collagen, and vitronectin.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell surface {ECO:0000250}.
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DR   EMBL; BX571857; CAG42528.1; -; Genomic_DNA.
DR   RefSeq; WP_000728062.1; NC_002953.3.
DR   AlphaFoldDB; Q6GB43; -.
DR   KEGG; sas:SAS0754; -.
DR   HOGENOM; CLU_078520_0_0_9; -.
DR   OMA; MINHYFA; -.
DR   GO; GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Signal.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000250"
FT   CHAIN           27..340
FT                   /note="Extracellular matrix protein-binding protein emp"
FT                   /id="PRO_0000271539"
SQ   SEQUENCE   340 AA;  38452 MW;  AD81DB33941347FD CRC64;
     MKKKLLVLTM STLFATQIMN SNHAKASVTE SVDKKFVVPE SGINKIIPTY NEFKKAPKVN
     VGNLADNKNF VASEDKLNKI VDSSAASKIV DKNFAVPESK LGNIVPEYKE INNRVNVATN
     NPASQQVDKH FVAKGPEVNR FITQNKVNHH FITTQTHYKK VITSYKSTHV HKHVNHAKDS
     INKHFIVKPS ESPRYTHPSQ SLIIKHHFAV PGYHAHKFVT PGHASIKINH FCVVPQINSF
     KVIPPYGHNS HRMHVPSFQN NTTATHQNAK VNKAYDYKYF YSYKVVKGVK KYFSFSQSNG
     YKIGKPSLNI KNVNYQYAVP SYSPTHYVPE FKGSLPAPRV