END1_BUCBP
ID END1_BUCBP Reviewed; 245 AA.
AC Q89AD7;
DT 16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=Endonuclease-1;
DE EC=3.1.21.1;
DE AltName: Full=Endonuclease I;
DE Short=Endo I;
GN Name=endA; OrderedLocusNames=bbp_369;
OS Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Buchnera.
OX NCBI_TaxID=224915;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bp;
RX PubMed=12522265; DOI=10.1073/pnas.0235981100;
RA van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F.,
RA Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J.,
RA Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A.;
RT "Reductive genome evolution in Buchnera aphidicola.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003).
CC -!- FUNCTION: Has double-strand break activity. {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endonucleolytic cleavage to 5'-phosphodinucleotide and 5'-
CC phosphooligonucleotide end-products.; EC=3.1.21.1;
CC -!- SIMILARITY: Belongs to the EndA/NucM nuclease family. {ECO:0000305}.
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DR EMBL; AE016826; AAO27086.1; -; Genomic_DNA.
DR RefSeq; WP_011091487.1; NC_004545.1.
DR AlphaFoldDB; Q89AD7; -.
DR SMR; Q89AD7; -.
DR STRING; 224915.bbp_369; -.
DR PRIDE; Q89AD7; -.
DR EnsemblBacteria; AAO27086; AAO27086; bbp_369.
DR GeneID; 56470908; -.
DR KEGG; bab:bbp_369; -.
DR eggNOG; COG2356; Bacteria.
DR HOGENOM; CLU_070541_0_0_6; -.
DR OMA; QSTEFYC; -.
DR OrthoDB; 1114630at2; -.
DR Proteomes; UP000000601; Chromosome.
DR GO; GO:0004530; F:deoxyribonuclease I activity; IEA:UniProtKB-EC.
DR InterPro; IPR007346; Endonuclease-I.
DR InterPro; IPR044925; His-Me_finger_sf.
DR PANTHER; PTHR33607; PTHR33607; 1.
DR Pfam; PF04231; Endonuclease_1; 1.
DR SUPFAM; SSF54060; SSF54060; 1.
PE 3: Inferred from homology;
KW Endonuclease; Hydrolase; Nuclease; Reference proteome.
FT CHAIN 1..245
FT /note="Endonuclease-1"
FT /id="PRO_0000207692"
SQ SEQUENCE 245 AA; 29154 MW; 7BBA5E03468B4318 CRC64;
MLIRSIFFFT ILIFSTCLSS NENIKHHYHK NFNQIKKLAQ KINIDAPGTF YCGCKIFWKE
KKGIPELNSC GYHIRKNANR ANRIEWEHVM PAWQFGHSKS CWKKGGRKNC IHDYNYQKIE
TDLHNLQPVI GEINGDRSNF MYNQFPKSTL NGQYGQCSMK IDFKNKLVEP PDISKGAISR
IYFYMSDFYH FKLSKKQKKL FLMWNKKYNV TNWECMRDNL IFKIQGNHNP YVYSKCQKNN
TNKNI