ID   END2_ONCKE              Reviewed;          30 AA.
AC   P01205;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=Beta-endorphin-2;
DE   AltName: Full=Beta-endorphin II;
DE   Contains:
DE     RecName: Full=Met-enkephalin;
OS   Oncorhynchus keta (Chum salmon) (Salmo keta).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Oncorhynchus.
OX   NCBI_TaxID=8018;
RN   [1]
RP   PROTEIN SEQUENCE, AND ACETYLATION AT TYR-1.
RX   PubMed=7370035; DOI=10.1016/0006-291x(80)90425-8;
RA   Kawauchi H., Tsubokawa M., Kanezawa A., Kitagawa H.;
RT   "Occurrence of two different endorphins in the salmon pituitary.";
RL   Biochem. Biophys. Res. Commun. 92:1278-1288(1980).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the POMC family. {ECO:0000305}.
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DR   PIR; A01469; OEON2K.
DR   AlphaFoldDB; P01205; -.
DR   SMR; P01205; -.
DR   iPTMnet; P01205; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR013532; Opioid_neuropept.
DR   Pfam; PF08035; Op_neuropeptide; 1.
DR   SMART; SM01365; Op_neuropeptide; 1.
PE   1: Evidence at protein level;
KW   Acetylation; Direct protein sequencing; Endorphin; Secreted.
FT   PEPTIDE         1..30
FT                   /note="Beta-endorphin-2"
FT                   /id="PRO_0000044575"
FT   PEPTIDE         1..5
FT                   /note="Met-enkephalin"
FT                   /id="PRO_0000025092"
FT   MOD_RES         1
FT                   /note="N-acetyltyrosine"
FT                   /evidence="ECO:0000269|PubMed:7370035"
SQ   SEQUENCE   30 AA;  3527 MW;  98F68D5EB383D210 CRC64;
     YGGFMKSWNE RSQKPLLTLF KNVIIKDGQQ