ID   AGD15_ARATH             Reviewed;         232 AA.
AC   Q0WQQ1; Q9LUN1;
DT   14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Probable ADP-ribosylation factor GTPase-activating protein AGD15;
DE            Short=ARF GAP AGD15;
DE   AltName: Full=Protein ARF-GAP DOMAIN 15;
DE            Short=AtAGD15;
GN   Name=AGD15; OrderedLocusNames=At3g17660; ORFNames=MKP6.22;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA   Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT   features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT   clones.";
RL   DNA Res. 7:131-135(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA   Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA   Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA   Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA   Shinozaki K.;
RT   "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL   Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=12644670; DOI=10.1104/pp.013052;
RA   Vernoud V., Horton A.C., Yang Z., Nielsen E.;
RT   "Analysis of the small GTPase gene superfamily of Arabidopsis.";
RL   Plant Physiol. 131:1191-1208(2003).
CC   -!- FUNCTION: GTPase-activating protein (GAP) for ADP ribosylation factor
CC       (ARF). {ECO:0000250}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB02056.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AB022219; BAB02056.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002686; AEE75986.1; -; Genomic_DNA.
DR   EMBL; AK228639; BAF00548.1; -; mRNA.
DR   RefSeq; NP_188393.2; NM_112647.4.
DR   AlphaFoldDB; Q0WQQ1; -.
DR   SMR; Q0WQQ1; -.
DR   STRING; 3702.AT3G17660.1; -.
DR   iPTMnet; Q0WQQ1; -.
DR   PaxDb; Q0WQQ1; -.
DR   ProteomicsDB; 244673; -.
DR   EnsemblPlants; AT3G17660.1; AT3G17660.1; AT3G17660.
DR   GeneID; 821033; -.
DR   Gramene; AT3G17660.1; AT3G17660.1; AT3G17660.
DR   KEGG; ath:AT3G17660; -.
DR   Araport; AT3G17660; -.
DR   TAIR; locus:2090517; AT3G17660.
DR   eggNOG; KOG0703; Eukaryota.
DR   HOGENOM; CLU_023062_8_0_1; -.
DR   InParanoid; Q0WQQ1; -.
DR   PhylomeDB; Q0WQQ1; -.
DR   PRO; PR:Q0WQQ1; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q0WQQ1; baseline and differential.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.220.150; -; 1.
DR   InterPro; IPR044520; ARF_GAP_AGD5/15.
DR   InterPro; IPR037278; ARFGAP/RecO.
DR   InterPro; IPR001164; ArfGAP_dom.
DR   InterPro; IPR038508; ArfGAP_dom_sf.
DR   PANTHER; PTHR46419; PTHR46419; 1.
DR   Pfam; PF01412; ArfGap; 1.
DR   PRINTS; PR00405; REVINTRACTNG.
DR   SMART; SM00105; ArfGap; 1.
DR   SUPFAM; SSF57863; SSF57863; 1.
DR   PROSITE; PS50115; ARFGAP; 1.
PE   2: Evidence at transcript level;
KW   GTPase activation; Metal-binding; Reference proteome; Zinc; Zinc-finger.
FT   CHAIN           1..232
FT                   /note="Probable ADP-ribosylation factor GTPase-activating
FT                   protein AGD15"
FT                   /id="PRO_0000352506"
FT   DOMAIN          16..130
FT                   /note="Arf-GAP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00288"
FT   ZN_FING         31..54
FT                   /note="C4-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00288"
FT   REGION          203..232
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        204..232
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   232 AA;  26210 MW;  E20CDC87505D3B45 CRC64;
     MNRKASVSKE LNAKHSKILE ALLKHPDNRE CADCRSKAPR WASVNLGIFI CMQCSGIHRS
     LGVHISQVRS ITLDTWLPDQ VAFMKSTGNA KGNEYWESEL PQHFERSSSD TFIRAKYSEK
     RWVSPGAIQP APIVSQLSCK VSHLVESGYK PETPKKARTL SLDEEILLHH VLQVTPPETR
     TRAGSVDMKE NVYVVPLPEF KKPNQKNENF SSEVNQNRRT TIAPPSSWAT FD