ENDR_PAEPO
ID ENDR_PAEPO Reviewed; 340 AA.
AC P27871;
DT 01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1992, sequence version 1.
DT 25-MAY-2022, entry version 89.
DE RecName: Full=Probable HTH-type transcriptional regulator EndR;
GN Name=endR;
OS Paenibacillus polymyxa (Bacillus polymyxa).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1406;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2307659; DOI=10.1128/jb.172.3.1576-1586.1990;
RA Baird S.D., Johnson D.A., Seligy V.L.;
RT "Molecular cloning, expression, and characterization of endo-beta-1,4-
RT glucanase genes from Bacillus polymyxa and Bacillus circulans.";
RL J. Bacteriol. 172:1576-1586(1990).
RN [2]
RP SEQUENCE REVISION.
RX PubMed=1639817; DOI=10.1016/s0021-9258(19)49615-4;
RA Weickert M.J., Adhya S.;
RT "A family of bacterial regulators homologous to Gal and Lac repressors.";
RL J. Biol. Chem. 267:15869-15874(1992).
CC -!- FUNCTION: Putative repressor of the endoglucanase operon.
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DR EMBL; M33791; AAA22630.1; ALT_SEQ; Genomic_DNA.
DR PIR; B35136; B35136.
DR AlphaFoldDB; P27871; -.
DR SMR; P27871; -.
DR STRING; 1052684.PPM_3721; -.
DR eggNOG; COG1609; Bacteria.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR Gene3D; 1.10.260.40; -; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; SSF47413; 1.
DR SUPFAM; SSF53822; SSF53822; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding; Repressor; Transcription; Transcription regulation.
FT CHAIN 1..340
FT /note="Probable HTH-type transcriptional regulator EndR"
FT /id="PRO_0000107944"
FT DOMAIN 1..58
FT /note="HTH lacI-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00111"
FT DNA_BIND 5..24
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00111"
SQ SEQUENCE 340 AA; 38651 MW; FB38623CEC10BC66 CRC64;
MVTTMKEVAE RAGVSKSTVS QFLQKRYNYM SENTKKKIEQ AIEDLSYIPN EVARSLKQKK
TFIVGVISST ILSRFTTEVV RAIEDECQLE NVQVIVCNTD DDSLKEKKYV QSMIARQVDG
LIIFPTEENK KLYVSLVKNG YPFVFVDRKI DELSVDTVLL NNEKASRACV EALIEHGHNN
IGIITFPLGK KAITTRSERL SGYRNTLGKH DIPVNENYIK SGRLDEMPNL IGQLFHMENP
PTAIIATNDM ILEQVLIYAK NNHLTIPNDF SLIGIDDVSF ASFYNPPITT VSQPSFEMGK
RSARLLLEKI DQKEQDHEEL SEIIRMNPVI NHRESVLKLN