ENGB_BURTA
ID ENGB_BURTA Reviewed; 219 AA.
AC Q2SU58;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 12-DEC-2006, sequence version 2.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=Probable GTP-binding protein EngB {ECO:0000255|HAMAP-Rule:MF_00321};
GN Name=engB {ECO:0000255|HAMAP-Rule:MF_00321}; OrderedLocusNames=BTH_I3037;
OS Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 /
OS E264).
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; pseudomallei group.
OX NCBI_TaxID=271848;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700388 / DSM 13276 / CIP 106301 / E264;
RX PubMed=16336651; DOI=10.1186/1471-2164-6-174;
RA Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C.,
RA DeShazer D.;
RT "Bacterial genome adaptation to niches: divergence of the potential
RT virulence genes in three Burkholderia species of different survival
RT strategies.";
RL BMC Genomics 6:174-174(2005).
CC -!- FUNCTION: Necessary for normal cell division and for the maintenance of
CC normal septation. {ECO:0000255|HAMAP-Rule:MF_00321}.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00321};
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. EngB GTPase family. {ECO:0000255|HAMAP-
CC Rule:MF_00321}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABC39144.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; CP000086; ABC39144.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_009888451.1; NZ_CP008786.1.
DR PDB; 4DHE; X-ray; 2.20 A; A/B=1-219.
DR PDBsum; 4DHE; -.
DR AlphaFoldDB; Q2SU58; -.
DR SMR; Q2SU58; -.
DR PRIDE; Q2SU58; -.
DR EnsemblBacteria; ABC39144; ABC39144; BTH_I3037.
DR KEGG; bte:BTH_I3037; -.
DR HOGENOM; CLU_033732_1_1_4; -.
DR OrthoDB; 1746051at2; -.
DR Proteomes; UP000001930; Chromosome I.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR CDD; cd01876; YihA_EngB; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR HAMAP; MF_00321; GTPase_EngB; 1.
DR InterPro; IPR030393; G_ENGB_dom.
DR InterPro; IPR006073; GTP-bd.
DR InterPro; IPR019987; GTP-bd_ribosome_bio_YsxC.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF01926; MMR_HSR1; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR03598; GTPase_YsxC; 1.
DR PROSITE; PS51706; G_ENGB; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cell cycle; Cell division; GTP-binding; Magnesium;
KW Metal-binding; Nucleotide-binding; Septation.
FT CHAIN 1..219
FT /note="Probable GTP-binding protein EngB"
FT /id="PRO_0000266837"
FT DOMAIN 24..207
FT /note="EngB-type G"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00321"
FT BINDING 32..39
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00321"
FT BINDING 39
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00321"
FT BINDING 59..63
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00321"
FT BINDING 61
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00321"
FT BINDING 81..84
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00321"
FT BINDING 148..151
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00321"
FT BINDING 185..188
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00321"
FT HELIX 1..6
FT /evidence="ECO:0007829|PDB:4DHE"
FT STRAND 9..14
FT /evidence="ECO:0007829|PDB:4DHE"
FT HELIX 17..19
FT /evidence="ECO:0007829|PDB:4DHE"
FT STRAND 27..33
FT /evidence="ECO:0007829|PDB:4DHE"
FT HELIX 35..45
FT /evidence="ECO:0007829|PDB:4DHE"
FT STRAND 49..52
FT /evidence="ECO:0007829|PDB:4DHE"
FT STRAND 64..70
FT /evidence="ECO:0007829|PDB:4DHE"
FT STRAND 76..81
FT /evidence="ECO:0007829|PDB:4DHE"
FT HELIX 94..108
FT /evidence="ECO:0007829|PDB:4DHE"
FT STRAND 112..120
FT /evidence="ECO:0007829|PDB:4DHE"
FT HELIX 127..136
FT /evidence="ECO:0007829|PDB:4DHE"
FT HELIX 137..139
FT /evidence="ECO:0007829|PDB:4DHE"
FT STRAND 143..148
FT /evidence="ECO:0007829|PDB:4DHE"
FT HELIX 150..152
FT /evidence="ECO:0007829|PDB:4DHE"
FT HELIX 155..175
FT /evidence="ECO:0007829|PDB:4DHE"
FT STRAND 181..187
FT /evidence="ECO:0007829|PDB:4DHE"
FT TURN 188..191
FT /evidence="ECO:0007829|PDB:4DHE"
FT HELIX 194..205
FT /evidence="ECO:0007829|PDB:4DHE"
SQ SEQUENCE 219 AA; 24207 MW; 700149DD587B26AC CRC64;
MAFLLHQARF FTTVNHLRDL PPTVQPEIAF AGRSNAGKST AINVLCNQKR LAFASKTPGR
TQHINYFSVG PAAEPVAHLV DLPGYGYAEV PGAAKAHWEQ LLSSYLQTRP QLCGMILMMD
ARRPLTELDR RMIEWFAPTG KPIHSLLTKC DKLTRQESIN ALRATQKSLD AYRDAGYAGK
LTVQLFSALK RTGLDDAHAL IESWLRPAAA DEDHAAVAE
