ENGB_CAUVC
ID ENGB_CAUVC Reviewed; 229 AA.
AC Q9ZG89;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 14-OCT-2015, sequence version 3.
DT 03-AUG-2022, entry version 127.
DE RecName: Full=GTP-binding protein EngB;
DE AltName: Full=GTP-binding protein CgpA;
GN Name=engB {ECO:0000255|HAMAP-Rule:MF_00321}; Synonyms=cgpA;
GN OrderedLocusNames=CC_0766;
OS Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Caulobacter.
OX NCBI_TaxID=190650;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19089 / CB15;
RX PubMed=11259647; DOI=10.1073/pnas.061029298;
RA Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E.,
RA Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R.,
RA Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B.,
RA DeBoy R.T., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F.,
RA Smit J., Craven M.B., Khouri H.M., Shetty J., Berry K.J., Utterback T.R.,
RA Tran K., Wolf A.M., Vamathevan J.J., Ermolaeva M.D., White O.,
RA Salzberg S.L., Venter J.C., Shapiro L., Fraser C.M.;
RT "Complete genome sequence of Caulobacter crescentus.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 25-229.
RA Easter J. Jr., Gober J.W.;
RT "Caulobacter crescentus GTP-binding protein CgpA.";
RL Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Necessary for normal cell division and for the maintenance of
CC normal septation. {ECO:0000255|HAMAP-Rule:MF_00321}.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00321};
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. EngB GTPase family. {ECO:0000255|HAMAP-
CC Rule:MF_00321}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC69623.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=AAK22751.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AE005673; AAK22751.1; ALT_INIT; Genomic_DNA.
DR EMBL; AF084242; AAC69623.1; ALT_INIT; Genomic_DNA.
DR PIR; C87344; C87344.
DR RefSeq; NP_419583.1; NC_002696.2.
DR RefSeq; WP_024265621.1; NC_002696.2.
DR AlphaFoldDB; Q9ZG89; -.
DR SMR; Q9ZG89; -.
DR STRING; 190650.CC_0766; -.
DR EnsemblBacteria; AAK22751; AAK22751; CC_0766.
DR KEGG; ccr:CC_0766; -.
DR PATRIC; fig|190650.5.peg.777; -.
DR eggNOG; COG0218; Bacteria.
DR HOGENOM; CLU_033732_2_0_5; -.
DR BioCyc; CAULO:CC0766-MON; -.
DR Proteomes; UP000001816; Chromosome.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR CDD; cd01876; YihA_EngB; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR HAMAP; MF_00321; GTPase_EngB; 1.
DR InterPro; IPR030393; G_ENGB_dom.
DR InterPro; IPR006073; GTP-bd.
DR InterPro; IPR019987; GTP-bd_ribosome_bio_YsxC.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF01926; MMR_HSR1; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR03598; GTPase_YsxC; 1.
DR PROSITE; PS51706; G_ENGB; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; GTP-binding; Magnesium; Metal-binding;
KW Nucleotide-binding; Reference proteome; Septation.
FT CHAIN 1..229
FT /note="GTP-binding protein EngB"
FT /id="PRO_0000157743"
FT DOMAIN 53..228
FT /note="EngB-type G"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00321"
FT BINDING 61..68
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00321"
FT BINDING 68
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00321"
FT BINDING 88..92
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00321"
FT BINDING 90
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00321"
FT BINDING 106..109
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00321"
FT BINDING 173..176
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00321"
FT BINDING 207..209
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00321"
FT CONFLICT 92
FT /note="E -> Q (in Ref. 1; AAC69623)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 229 AA; 25151 MW; 441A1DC7242AF2BA CRC64;
MSEEQKLPKE PPILLPGAAD FTEEQIEAAR VFFAQPVSFI MGAVRMDAMP PSDLPEVAFA
GRSNVGKSSL INGLVNQKYL ARASNEPGRT REINFFLLAE KVRLVDLPGY GFARVSRSIA
DKFQDLGRAY LRGRANLKRV YVLIDARHGL KKVDLEALDA LDVAAVSYQI VLTKADKIKP
AEVDKVVAET QKAIAKRAAA FPRVLATSSE KGLGMPELRA EIVRLCIDE
