位置:首页 > 蛋白库 > ENLYS_BPT4
ENLYS_BPT4
ID   ENLYS_BPT4              Reviewed;         164 AA.
AC   P00720; Q38170; Q94N07;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   14-MAY-2014, sequence version 2.
DT   03-AUG-2022, entry version 202.
DE   RecName: Full=Endolysin {ECO:0000255|HAMAP-Rule:MF_04110};
DE            EC=3.2.1.17 {ECO:0000255|HAMAP-Rule:MF_04110, ECO:0000269|PubMed:4865643};
DE   AltName: Full=Lysis protein {ECO:0000255|HAMAP-Rule:MF_04110};
DE   AltName: Full=Lysozyme {ECO:0000255|HAMAP-Rule:MF_04110};
DE   AltName: Full=Muramidase {ECO:0000255|HAMAP-Rule:MF_04110};
GN   Name=E;
OS   Enterobacteria phage T4 (Bacteriophage T4).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
OX   NCBI_TaxID=10665;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=5470817; DOI=10.1016/s0021-9258(18)62953-9;
RA   Inouye M., Imada M., Tsugita A.;
RT   "The amino acid sequence of T4 phage lysozyme. IV. Dilute acid hydrolysis
RT   and the order of tryptic peptides.";
RL   J. Biol. Chem. 245:3479-3484(1970).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=6302287; DOI=10.1016/s0022-2836(83)80255-1;
RA   Owen J.E., Schultz D.W., Taylor A., Smith G.R.;
RT   "Nucleotide sequence of the lysozyme gene of bacteriophage T4. Analysis of
RT   mutations involving repeated sequences.";
RL   J. Mol. Biol. 165:229-248(1983).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3024113; DOI=10.1093/nar/14.21.8637;
RA   Valerie K., Stevens J., Lynch M., Henderson E.E., de Riel J.K.;
RT   "Nucleotide sequence and analysis of the 58.3 to 65.5-kb early region of
RT   bacteriophage T4.";
RL   Nucleic Acids Res. 14:8637-8654(1986).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12626685; DOI=10.1128/mmbr.67.1.86-156.2003;
RA   Miller E.S., Kutter E., Mosig G., Arisaka F., Kunisawa T., Ruger W.;
RT   "Bacteriophage T4 genome.";
RL   Microbiol. Mol. Biol. Rev. 67:86-156(2003).
RN   [5]
RP   CATALYTIC ACTIVITY, AND BIOPHYSICOCHEMICAL PROPERTIES.
RX   PubMed=4865643; DOI=10.1016/s0021-9258(18)99306-3;
RA   Tsugita A., Inouye M.;
RT   "Purification of bacteriophage T4 lysozyme.";
RL   J. Biol. Chem. 243:391-397(1968).
RN   [6]
RP   MUTAGENESIS OF GLU-11 AND ASP-20, AND ACTIVE SITE.
RX   PubMed=3382407; DOI=10.1016/s0006-291x(88)81175-6;
RA   Anand N.N., Stephen E.R., Narang S.A.;
RT   "Mutation of active site residues in synthetic T4-lysozyme gene and their
RT   effect on lytic activity.";
RL   Biochem. Biophys. Res. Commun. 153:862-868(1988).
RN   [7]
RP   ACTIVE SITE, AND MUTAGENESIS OF ASP-20.
RX   PubMed=1892846; DOI=10.1021/bi00103a010;
RA   Hardy L.W., Poteete A.R.;
RT   "Reexamination of the role of Asp20 in catalysis by bacteriophage T4
RT   lysozyme.";
RL   Biochemistry 30:9457-9463(1991).
RN   [8]
RP   FUNCTION.
RX   PubMed=22389108; DOI=10.1002/pro.2042;
RA   Moussa S.H., Kuznetsov V., Tran T.A., Sacchettini J.C., Young R.;
RT   "Protein determinants of phage T4 lysis inhibition.";
RL   Protein Sci. 21:571-582(2012).
RN   [9]
RP   X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS).
RX   PubMed=4530293; DOI=10.1073/pnas.71.10.4178;
RA   Matthews B.W., Remington S.J.;
RT   "The three dimensional structure of the lysozyme from bacteriophage T4.";
RL   Proc. Natl. Acad. Sci. U.S.A. 71:4178-4182(1974).
RN   [10]
RP   X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS).
RX   PubMed=3586019; DOI=10.1016/0022-2836(87)90636-x;
RA   Weaver L.H., Matthews B.W.;
RT   "Structure of bacteriophage T4 lysozyme refined at 1.7-A resolution.";
RL   J. Mol. Biol. 193:189-200(1987).
RN   [11]
RP   X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS).
RX   PubMed=322662; DOI=10.1016/0006-291x(77)91038-5;
RA   Remington S.J., ten Eyck L.F., Matthews B.W.;
RT   "Atomic coordinates for T4 phage lysozyme.";
RL   Biochem. Biophys. Res. Commun. 75:265-270(1977).
RN   [12]
RP   X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF MUTANT ILE-3.
RX   PubMed=3405287; DOI=10.1038/334406a0;
RA   Matsumura M., Becktel W.J., Matthews B.W.;
RT   "Hydrophobic stabilization in T4 lysozyme determined directly by multiple
RT   substitutions of Ile 3.";
RL   Nature 334:406-410(1988).
RN   [13]
RP   X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) OF MUTANT.
RX   PubMed=2234094; DOI=10.1038/348263a0;
RA   Faber H.R., Matthews B.W.;
RT   "A mutant T4 lysozyme displays five different crystal conformations.";
RL   Nature 348:263-266(1990).
RN   [14]
RP   X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF MUTANT.
RX   PubMed=1731252; DOI=10.1038/355371a0;
RA   Eriksson A.E., Baase W.A., Wozniak J.A., Matthews B.W.;
RT   "A cavity-containing mutant of T4 lysozyme is stabilized by buried
RT   benzene.";
RL   Nature 355:371-373(1992).
RN   [15]
RP   STRUCTURE BY NMR.
RX   PubMed=2207079; DOI=10.1021/bi00479a003;
RA   McIntosh L.P., Wand A.J., Lowry D.F., Redfield A.G., Dahlquist F.W.;
RT   "Assignment of the backbone 1H and 15N NMR resonances of bacteriophage T4
RT   lysozyme.";
RL   Biochemistry 29:6341-6362(1990).
RN   [16]
RP   X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) IN COMPLEX WITH
RP   N-ACETYL-D-GLUCOSAMINE, MUTAGENESIS OF THR-26, AND ACTIVE SITE.
RX   PubMed=8266098; DOI=10.1126/science.8266098;
RA   Kuroki R., Weaver L.H., Matthews B.W.;
RT   "A covalent enzyme-substrate intermediate with saccharide distortion in a
RT   mutant T4 lysozyme.";
RL   Science 262:2030-2033(1993).
RN   [17]
RP   X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS), MUTAGENESIS OF GLU-11; ASP-20;
RP   GLY-30; SER-117 AND ASN-132, AND ACTIVE SITE.
RX   PubMed=7831309; DOI=10.1073/pnas.92.2.452;
RA   Shoichet B.K., Baase W.A., Kuroki R., Matthews B.W.;
RT   "A relationship between protein stability and protein function.";
RL   Proc. Natl. Acad. Sci. U.S.A. 92:452-456(1995).
RN   [18] {ECO:0007744|PDB:5XPE, ECO:0007744|PDB:5XPF}
RP   X-RAY CRYSTALLOGRAPHY (1.04 ANGSTROMS), AND MUTAGENESIS OF THR-26.
RX   PubMed=28707339; DOI=10.1002/pro.3230;
RA   Hiromoto T., Meilleur F., Shimizu R., Shibazaki C., Adachi M., Tamada T.,
RA   Kuroki R.;
RT   "Neutron structure of the T26H mutant of T4 phage lysozyme provides insight
RT   into the catalytic activity of the mutant enzyme and how it differs from
RT   that of wild type.";
RL   Protein Sci. 26:1953-1963(2017).
CC   -!- FUNCTION: Endolysin with lysozyme activity that degrades host
CC       peptidoglycans and participates with the holin and spanin proteins in
CC       the sequential events which lead to the programmed host cell lysis
CC       releasing the mature viral particles. Once the holin has permeabilized
CC       the host cell membrane, the endolysin can reach the periplasm and break
CC       down the peptidoglycan layer. {ECO:0000255|HAMAP-Rule:MF_04110,
CC       ECO:0000269|PubMed:22389108}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic
CC         acid and N-acetyl-D-glucosamine residues in a peptidoglycan and
CC         between N-acetyl-D-glucosamine residues in chitodextrins.;
CC         EC=3.2.1.17; Evidence={ECO:0000255|HAMAP-Rule:MF_04110,
CC         ECO:0000269|PubMed:4865643};
CC   -!- BIOPHYSICOCHEMICAL PROPERTIES:
CC       pH dependence:
CC         Optimum pH is 7.3. {ECO:0000269|PubMed:4865643};
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000255|HAMAP-Rule:MF_04110}.
CC       Note=The endolysin is cytoplasmic, but can reach the periplasmic space
CC       with the help of the holins which disrupt the host cell membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_04110}.
CC   -!- INDUCTION: Expressed late in the viral replication.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 24 family.
CC       {ECO:0000255|HAMAP-Rule:MF_04110}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X04567; CAA28212.1; -; Genomic_DNA.
DR   EMBL; AF158101; AAD42568.1; -; Genomic_DNA.
DR   PIR; A92896; LZBPT4.
DR   RefSeq; NP_049736.1; NC_000866.4.
DR   PDB; 102L; X-ray; 1.74 A; A=1-164.
DR   PDB; 103L; X-ray; 1.90 A; A=1-164.
DR   PDB; 104L; X-ray; 2.80 A; A/B=1-164.
DR   PDB; 107L; X-ray; 1.80 A; A=1-164.
DR   PDB; 108L; X-ray; 1.80 A; A=1-164.
DR   PDB; 109L; X-ray; 1.85 A; A=1-164.
DR   PDB; 110L; X-ray; 1.70 A; A=1-164.
DR   PDB; 111L; X-ray; 1.80 A; A=1-164.
DR   PDB; 112L; X-ray; 1.80 A; A=1-164.
DR   PDB; 113L; X-ray; 1.80 A; A=1-164.
DR   PDB; 114L; X-ray; 1.80 A; A=1-164.
DR   PDB; 115L; X-ray; 1.80 A; A=1-164.
DR   PDB; 118L; X-ray; 1.80 A; A=1-164.
DR   PDB; 119L; X-ray; 1.65 A; A=1-164.
DR   PDB; 120L; X-ray; 1.80 A; A=1-164.
DR   PDB; 122L; X-ray; 1.80 A; A=1-164.
DR   PDB; 123L; X-ray; 1.80 A; A=1-164.
DR   PDB; 125L; X-ray; 1.85 A; A=1-164.
DR   PDB; 126L; X-ray; 1.80 A; A=1-164.
DR   PDB; 127L; X-ray; 1.85 A; A=1-164.
DR   PDB; 128L; X-ray; 1.70 A; A=1-164.
DR   PDB; 129L; X-ray; 1.70 A; A=1-164.
DR   PDB; 130L; X-ray; 1.70 A; A=1-164.
DR   PDB; 131L; X-ray; 1.70 A; A=1-164.
DR   PDB; 137L; X-ray; 1.85 A; A/B=1-164.
DR   PDB; 138L; X-ray; 1.70 A; A=1-164.
DR   PDB; 139L; X-ray; 1.70 A; A=1-164.
DR   PDB; 140L; X-ray; 2.10 A; A=1-164.
DR   PDB; 141L; X-ray; 2.00 A; A=1-164.
DR   PDB; 142L; X-ray; 2.00 A; A=1-164.
DR   PDB; 143L; X-ray; 2.00 A; A=1-164.
DR   PDB; 144L; X-ray; 2.10 A; A=1-164.
DR   PDB; 145L; X-ray; 2.00 A; A=1-164.
DR   PDB; 146L; X-ray; 1.85 A; A=1-164.
DR   PDB; 147L; X-ray; 2.00 A; A=1-164.
DR   PDB; 148L; X-ray; 1.90 A; E=1-164.
DR   PDB; 149L; X-ray; 2.60 A; A=1-164.
DR   PDB; 150L; X-ray; 2.20 A; A/B/C/D=1-164.
DR   PDB; 151L; X-ray; 2.20 A; A=1-164.
DR   PDB; 152L; X-ray; 2.00 A; A=1-163.
DR   PDB; 155L; X-ray; 1.85 A; A=1-164.
DR   PDB; 156L; X-ray; 1.80 A; A=1-164.
DR   PDB; 157L; X-ray; 1.85 A; A=1-164.
DR   PDB; 158L; X-ray; 1.80 A; A=1-164.
DR   PDB; 159L; X-ray; 1.80 A; A=1-164.
DR   PDB; 160L; X-ray; 1.80 A; A=1-164.
DR   PDB; 161L; X-ray; 1.70 A; A=1-164.
DR   PDB; 162L; X-ray; 1.80 A; A=1-164.
DR   PDB; 163L; X-ray; 1.80 A; A=1-164.
DR   PDB; 164L; X-ray; 1.80 A; A=1-164.
DR   PDB; 165L; X-ray; 1.75 A; A=1-164.
DR   PDB; 166L; X-ray; 1.75 A; A=1-164.
DR   PDB; 167L; X-ray; 2.20 A; A/B=1-163.
DR   PDB; 168L; X-ray; 2.90 A; A/B/C/D/E=1-164.
DR   PDB; 169L; X-ray; 3.00 A; A/B/C/D/E=1-164.
DR   PDB; 170L; X-ray; 2.60 A; A=1-164.
DR   PDB; 171L; X-ray; 2.50 A; A=1-164.
DR   PDB; 172L; X-ray; 1.90 A; A=1-164.
DR   PDB; 173L; X-ray; 1.70 A; A=1-164.
DR   PDB; 174L; X-ray; 2.30 A; A/B=1-164.
DR   PDB; 175L; X-ray; 2.10 A; A/B=1-164.
DR   PDB; 176L; X-ray; 2.20 A; A/B=1-164.
DR   PDB; 177L; X-ray; 2.50 A; A=1-164.
DR   PDB; 178L; X-ray; 2.71 A; A=1-164.
DR   PDB; 180L; X-ray; 1.75 A; A/B=1-164.
DR   PDB; 181L; X-ray; 1.80 A; A=1-164.
DR   PDB; 182L; X-ray; 1.80 A; A=1-164.
DR   PDB; 183L; X-ray; 1.80 A; A=1-164.
DR   PDB; 184L; X-ray; 1.80 A; A=1-164.
DR   PDB; 185L; X-ray; 1.80 A; A=1-164.
DR   PDB; 186L; X-ray; 1.80 A; A=1-164.
DR   PDB; 187L; X-ray; 1.80 A; A=1-164.
DR   PDB; 188L; X-ray; 1.80 A; A=1-164.
DR   PDB; 189L; X-ray; 2.50 A; A=1-164.
DR   PDB; 190L; X-ray; 2.00 A; A=1-164.
DR   PDB; 191L; X-ray; 1.95 A; A=1-164.
DR   PDB; 192L; X-ray; 1.90 A; A=1-164.
DR   PDB; 195L; X-ray; 1.90 A; A=1-164.
DR   PDB; 196L; X-ray; 2.30 A; A=1-164.
DR   PDB; 197L; X-ray; 2.10 A; A=1-164.
DR   PDB; 198L; X-ray; 2.00 A; A=1-164.
DR   PDB; 199L; X-ray; 1.85 A; A=1-164.
DR   PDB; 1B6I; X-ray; 1.90 A; A=1-164.
DR   PDB; 1C60; X-ray; 2.00 A; A=1-164.
DR   PDB; 1C61; X-ray; 2.00 A; A=1-164.
DR   PDB; 1C62; X-ray; 2.30 A; A=1-164.
DR   PDB; 1C63; X-ray; 2.00 A; A=1-164.
DR   PDB; 1C64; X-ray; 2.00 A; A=1-164.
DR   PDB; 1C65; X-ray; 2.00 A; A=1-164.
DR   PDB; 1C66; X-ray; 2.10 A; A=1-164.
DR   PDB; 1C67; X-ray; 2.20 A; A=1-164.
DR   PDB; 1C68; X-ray; 2.50 A; A=1-164.
DR   PDB; 1C69; X-ray; 1.80 A; A=1-164.
DR   PDB; 1C6A; X-ray; 2.10 A; A=1-164.
DR   PDB; 1C6B; X-ray; 2.20 A; A=1-164.
DR   PDB; 1C6C; X-ray; 2.00 A; A=1-164.
DR   PDB; 1C6D; X-ray; 2.00 A; A=1-164.
DR   PDB; 1C6E; X-ray; 1.90 A; A=1-164.
DR   PDB; 1C6F; X-ray; 2.00 A; A=1-164.
DR   PDB; 1C6G; X-ray; 1.90 A; A=1-164.
DR   PDB; 1C6H; X-ray; 1.90 A; A=1-164.
DR   PDB; 1C6I; X-ray; 1.90 A; A=1-164.
DR   PDB; 1C6J; X-ray; 1.90 A; A=1-164.
DR   PDB; 1C6K; X-ray; 1.90 A; A=1-164.
DR   PDB; 1C6L; X-ray; 1.90 A; A=1-164.
DR   PDB; 1C6M; X-ray; 2.10 A; A=1-164.
DR   PDB; 1C6N; X-ray; 2.20 A; A=1-164.
DR   PDB; 1C6P; X-ray; 1.90 A; A=1-164.
DR   PDB; 1C6Q; X-ray; 1.90 A; A=1-164.
DR   PDB; 1C6T; X-ray; 2.00 A; A=1-164.
DR   PDB; 1CTW; X-ray; 2.10 A; A=1-164.
DR   PDB; 1CU0; X-ray; 2.20 A; A=1-164.
DR   PDB; 1CU2; X-ray; 1.85 A; A=1-164.
DR   PDB; 1CU3; X-ray; 2.12 A; A=1-164.
DR   PDB; 1CU5; X-ray; 2.05 A; A=1-164.
DR   PDB; 1CU6; X-ray; 2.10 A; A=1-164.
DR   PDB; 1CUP; X-ray; 1.89 A; A=1-164.
DR   PDB; 1CUQ; X-ray; 2.05 A; A=1-164.
DR   PDB; 1CV0; X-ray; 2.12 A; A=1-164.
DR   PDB; 1CV1; X-ray; 2.10 A; A=1-164.
DR   PDB; 1CV3; X-ray; 1.80 A; A=1-164.
DR   PDB; 1CV4; X-ray; 1.90 A; A=1-164.
DR   PDB; 1CV5; X-ray; 1.87 A; A=1-164.
DR   PDB; 1CV6; X-ray; 1.90 A; A=1-164.
DR   PDB; 1CVK; X-ray; 1.80 A; A=1-164.
DR   PDB; 1CX6; X-ray; 2.01 A; A=1-164.
DR   PDB; 1CX7; X-ray; 1.94 A; A=1-164.
DR   PDB; 1D2W; X-ray; 1.89 A; A=1-164.
DR   PDB; 1D2Y; X-ray; 2.06 A; A=1-164.
DR   PDB; 1D3F; X-ray; 2.05 A; A=1-164.
DR   PDB; 1D3J; X-ray; 1.97 A; A=1-164.
DR   PDB; 1D3M; X-ray; 2.12 A; A=1-164.
DR   PDB; 1D3N; X-ray; 2.00 A; A=1-164.
DR   PDB; 1D9W; X-ray; 1.70 A; A=1-164.
DR   PDB; 1DYA; X-ray; 1.90 A; A=1-164.
DR   PDB; 1DYB; X-ray; 1.75 A; A=1-164.
DR   PDB; 1DYC; X-ray; 2.10 A; A=1-164.
DR   PDB; 1DYD; X-ray; 2.10 A; A=1-164.
DR   PDB; 1DYE; X-ray; 1.80 A; A=1-164.
DR   PDB; 1DYF; X-ray; 1.90 A; A=1-164.
DR   PDB; 1DYG; X-ray; 2.10 A; A=1-164.
DR   PDB; 1EPY; X-ray; 1.85 A; A=1-164.
DR   PDB; 1G06; X-ray; 1.85 A; A=1-164.
DR   PDB; 1G07; X-ray; 1.70 A; A=1-164.
DR   PDB; 1G0G; X-ray; 1.90 A; A=1-164.
DR   PDB; 1G0J; X-ray; 1.80 A; A=1-164.
DR   PDB; 1G0K; X-ray; 1.85 A; A=1-164.
DR   PDB; 1G0L; X-ray; 1.80 A; A=1-164.
DR   PDB; 1G0M; X-ray; 1.70 A; A=1-164.
DR   PDB; 1G0P; X-ray; 1.80 A; A=1-164.
DR   PDB; 1G0Q; X-ray; 1.80 A; A=1-164.
DR   PDB; 1G1V; X-ray; 1.90 A; A=1-164.
DR   PDB; 1G1W; X-ray; 1.80 A; A=1-164.
DR   PDB; 1I6S; X-ray; 1.90 A; A=1-164.
DR   PDB; 1JQU; X-ray; 2.60 A; A/B/C/D=1-164.
DR   PDB; 1JTM; X-ray; 1.90 A; A=1-164.
DR   PDB; 1JTN; X-ray; 2.30 A; A/B=1-164.
DR   PDB; 1KNI; X-ray; 1.70 A; A=1-164.
DR   PDB; 1KS3; X-ray; 2.16 A; A=1-162.
DR   PDB; 1KW5; X-ray; 1.75 A; A=1-162.
DR   PDB; 1KW7; X-ray; 1.89 A; A=1-162.
DR   PDB; 1KY0; X-ray; 1.97 A; A=1-162.
DR   PDB; 1KY1; X-ray; 2.05 A; A=1-162.
DR   PDB; 1L00; X-ray; 1.90 A; A=1-164.
DR   PDB; 1L01; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L02; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L03; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L04; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L05; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L06; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L07; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L08; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L09; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L0J; X-ray; 1.98 A; A=1-162.
DR   PDB; 1L0K; X-ray; 2.02 A; A=1-162.
DR   PDB; 1L10; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L11; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L12; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L13; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L14; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L15; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L16; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L17; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L18; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L19; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L20; X-ray; 1.85 A; A=1-164.
DR   PDB; 1L21; X-ray; 1.85 A; A=1-164.
DR   PDB; 1L22; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L23; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L24; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L25; X-ray; 1.80 A; A=1-164.
DR   PDB; 1L26; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L27; X-ray; 1.80 A; A=1-164.
DR   PDB; 1L28; X-ray; 1.90 A; A=1-164.
DR   PDB; 1L29; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L30; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L31; X-ray; 1.80 A; A=1-164.
DR   PDB; 1L32; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L33; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L34; X-ray; 1.90 A; A=1-164.
DR   PDB; 1L35; X-ray; 1.80 A; A=1-163.
DR   PDB; 1L36; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L37; X-ray; 1.85 A; A=1-164.
DR   PDB; 1L38; X-ray; 1.80 A; A=1-164.
DR   PDB; 1L39; X-ray; 1.85 A; A=1-164.
DR   PDB; 1L40; X-ray; 1.85 A; A=1-164.
DR   PDB; 1L41; X-ray; 1.75 A; A=1-164.
DR   PDB; 1L42; X-ray; 1.80 A; A=1-164.
DR   PDB; 1L43; X-ray; 1.80 A; A=1-164.
DR   PDB; 1L44; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L45; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L46; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L47; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L48; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L49; X-ray; 1.80 A; A=1-164.
DR   PDB; 1L50; X-ray; 1.85 A; A=1-164.
DR   PDB; 1L51; X-ray; 1.90 A; A=1-164.
DR   PDB; 1L52; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L53; X-ray; 1.85 A; A=1-164.
DR   PDB; 1L54; X-ray; 1.90 A; A=1-164.
DR   PDB; 1L55; X-ray; 1.90 A; A=1-164.
DR   PDB; 1L56; X-ray; 1.80 A; A=1-164.
DR   PDB; 1L57; X-ray; 1.90 A; A=1-164.
DR   PDB; 1L58; X-ray; 1.65 A; A=1-164.
DR   PDB; 1L59; X-ray; 1.75 A; A=1-164.
DR   PDB; 1L60; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L61; X-ray; 1.80 A; A=1-164.
DR   PDB; 1L62; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L63; X-ray; 1.75 A; A=1-164.
DR   PDB; 1L64; X-ray; 1.90 A; A=1-164.
DR   PDB; 1L65; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L66; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L67; X-ray; 1.90 A; A=1-164.
DR   PDB; 1L68; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L69; X-ray; 1.90 A; A=1-164.
DR   PDB; 1L70; X-ray; 1.90 A; A=1-164.
DR   PDB; 1L71; X-ray; 1.85 A; A=1-164.
DR   PDB; 1L72; X-ray; 1.85 A; A=1-164.
DR   PDB; 1L73; X-ray; 1.85 A; A=1-164.
DR   PDB; 1L74; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L75; X-ray; 1.90 A; A=1-164.
DR   PDB; 1L76; X-ray; 1.90 A; A=1-164.
DR   PDB; 1L77; X-ray; 2.05 A; A=1-164.
DR   PDB; 1L79; X-ray; 1.90 A; A=1-164.
DR   PDB; 1L80; X-ray; 1.80 A; A=1-164.
DR   PDB; 1L81; X-ray; 2.00 A; A=1-164.
DR   PDB; 1L82; X-ray; 2.10 A; A=1-164.
DR   PDB; 1L83; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L84; X-ray; 1.90 A; A=1-164.
DR   PDB; 1L85; X-ray; 2.00 A; A=1-164.
DR   PDB; 1L86; X-ray; 1.80 A; A=1-164.
DR   PDB; 1L87; X-ray; 1.80 A; A=1-164.
DR   PDB; 1L88; X-ray; 1.85 A; A=1-164.
DR   PDB; 1L89; X-ray; 1.90 A; A=1-164.
DR   PDB; 1L90; X-ray; 1.75 A; A=1-164.
DR   PDB; 1L91; X-ray; 1.80 A; A=1-164.
DR   PDB; 1L92; X-ray; 1.70 A; A=1-164.
DR   PDB; 1L93; X-ray; 1.80 A; A=1-164.
DR   PDB; 1L94; X-ray; 1.80 A; A=1-164.
DR   PDB; 1L95; X-ray; 2.00 A; A=1-164.
DR   PDB; 1L96; X-ray; 2.00 A; A=1-164.
DR   PDB; 1L97; X-ray; 2.00 A; A/B=1-164.
DR   PDB; 1L98; X-ray; 1.80 A; A=1-164.
DR   PDB; 1L99; X-ray; 1.95 A; A=1-164.
DR   PDB; 1LGU; X-ray; 1.90 A; A=1-164.
DR   PDB; 1LGW; X-ray; 1.85 A; A=1-164.
DR   PDB; 1LGX; X-ray; 1.90 A; A=1-164.
DR   PDB; 1LI2; X-ray; 2.00 A; A=1-164.
DR   PDB; 1LI3; X-ray; 1.85 A; A=1-164.
DR   PDB; 1LI6; X-ray; 2.00 A; A=1-164.
DR   PDB; 1LLH; X-ray; 1.80 A; A=1-164.
DR   PDB; 1LPY; X-ray; 1.65 A; A=1-164.
DR   PDB; 1LW9; X-ray; 1.45 A; A=1-164.
DR   PDB; 1LWG; X-ray; 1.70 A; A=1-164.
DR   PDB; 1LWK; X-ray; 2.10 A; A=1-164.
DR   PDB; 1LYD; X-ray; 2.00 A; A=1-164.
DR   PDB; 1LYE; X-ray; 1.80 A; A=1-164.
DR   PDB; 1LYF; X-ray; 1.80 A; A=1-164.
DR   PDB; 1LYG; X-ray; 1.80 A; A=1-164.
DR   PDB; 1LYH; X-ray; 1.70 A; A=1-164.
DR   PDB; 1LYI; X-ray; 2.00 A; A=1-164.
DR   PDB; 1LYJ; X-ray; 1.80 A; A=1-164.
DR   PDB; 1NHB; X-ray; 1.80 A; A=1-164.
DR   PDB; 1OV5; X-ray; 2.10 A; A=1-164.
DR   PDB; 1OV7; X-ray; 2.00 A; A=1-164.
DR   PDB; 1OVH; X-ray; 1.95 A; A=1-164.
DR   PDB; 1OVJ; X-ray; 2.00 A; A=1-164.
DR   PDB; 1OVK; X-ray; 2.10 A; A=1-164.
DR   PDB; 1OWY; X-ray; 1.90 A; A=1-164.
DR   PDB; 1OWZ; X-ray; 1.90 A; A=1-164.
DR   PDB; 1OYU; X-ray; 2.50 A; A/B=1-164.
DR   PDB; 1P2L; X-ray; 1.58 A; A=1-164.
DR   PDB; 1P2R; X-ray; 1.58 A; A=1-164.
DR   PDB; 1P36; X-ray; 1.45 A; A=1-164.
DR   PDB; 1P37; X-ray; 1.57 A; A=1-164.
DR   PDB; 1P3N; X-ray; 1.55 A; A=1-164.
DR   PDB; 1P46; X-ray; 1.67 A; A=1-164.
DR   PDB; 1P56; X-ray; 1.80 A; A=1-162.
DR   PDB; 1P5C; X-ray; 2.50 A; A/B/C/D=12-163.
DR   PDB; 1P64; X-ray; 1.62 A; A=1-164.
DR   PDB; 1P6Y; X-ray; 1.54 A; A=1-164.
DR   PDB; 1P7S; X-ray; 1.50 A; A=1-164.
DR   PDB; 1PQD; X-ray; 1.65 A; A=1-164.
DR   PDB; 1PQI; X-ray; 1.57 A; A=1-164.
DR   PDB; 1PQJ; X-ray; 1.90 A; A=1-164.
DR   PDB; 1PQK; X-ray; 2.00 A; A/B/C=1-164.
DR   PDB; 1PQM; X-ray; 1.52 A; A=1-164.
DR   PDB; 1PQO; X-ray; 1.65 A; A=1-164.
DR   PDB; 1QS5; X-ray; 2.50 A; A=1-162.
DR   PDB; 1QS9; X-ray; 1.85 A; A=1-162.
DR   PDB; 1QSB; X-ray; 1.80 A; A=1-162.
DR   PDB; 1QSQ; X-ray; 1.90 A; A=1-164.
DR   PDB; 1QT3; X-ray; 1.85 A; A=1-164.
DR   PDB; 1QT4; X-ray; 2.10 A; A=1-164.
DR   PDB; 1QT5; X-ray; 1.80 A; A=1-164.
DR   PDB; 1QT6; X-ray; 1.90 A; A=1-164.
DR   PDB; 1QT7; X-ray; 1.80 A; A=1-164.
DR   PDB; 1QT8; X-ray; 1.90 A; A=1-164.
DR   PDB; 1QTB; X-ray; 1.90 A; A=1-162.
DR   PDB; 1QTC; X-ray; 2.50 A; A=1-162.
DR   PDB; 1QTD; X-ray; 2.50 A; A=1-162.
DR   PDB; 1QTH; X-ray; 1.90 A; A/B=1-164.
DR   PDB; 1QTV; X-ray; 2.30 A; A=1-164.
DR   PDB; 1QTZ; X-ray; 2.00 A; A=1-164.
DR   PDB; 1QUD; X-ray; 1.75 A; A=1-162.
DR   PDB; 1QUG; X-ray; 1.90 A; A=1-162.
DR   PDB; 1QUH; X-ray; 1.85 A; A=1-162.
DR   PDB; 1QUO; X-ray; 1.90 A; A=1-162.
DR   PDB; 1SSW; X-ray; 2.13 A; A=1-164.
DR   PDB; 1SSY; X-ray; 2.40 A; A/B=1-164.
DR   PDB; 1SWY; X-ray; 1.06 A; A=1-164.
DR   PDB; 1SWZ; X-ray; 1.06 A; A=1-164.
DR   PDB; 1SX2; X-ray; 1.06 A; A=1-164.
DR   PDB; 1SX7; X-ray; 1.06 A; A=1-164.
DR   PDB; 1T6H; X-ray; 2.01 A; A=1-164.
DR   PDB; 1T8A; X-ray; 2.00 A; A=1-164.
DR   PDB; 1T8F; X-ray; 2.15 A; A=1-164.
DR   PDB; 1T8G; X-ray; 1.80 A; A=1-164.
DR   PDB; 1T97; X-ray; 2.70 A; A/B=1-164.
DR   PDB; 1TLA; X-ray; 2.00 A; A=1-164.
DR   PDB; 1XEP; X-ray; 1.55 A; A=1-164.
DR   PDB; 1ZUR; X-ray; 1.60 A; A=1-164.
DR   PDB; 1ZWN; X-ray; 1.80 A; A=1-164.
DR   PDB; 1ZYT; X-ray; 1.70 A; A=1-164.
DR   PDB; 200L; X-ray; 1.95 A; A=1-164.
DR   PDB; 201L; X-ray; 2.00 A; A/B=1-164.
DR   PDB; 205L; X-ray; 2.10 A; A=1-164.
DR   PDB; 206L; X-ray; 1.75 A; A=1-164.
DR   PDB; 209L; X-ray; 2.70 A; A=1-164.
DR   PDB; 210L; X-ray; 1.89 A; A=1-164.
DR   PDB; 211L; X-ray; 1.70 A; A=1-164.
DR   PDB; 212L; X-ray; 1.76 A; A=1-164.
DR   PDB; 213L; X-ray; 2.13 A; A=1-164.
DR   PDB; 214L; X-ray; 1.89 A; A=1-164.
DR   PDB; 215L; X-ray; 1.96 A; A=1-164.
DR   PDB; 216L; X-ray; 2.10 A; A/B=1-164.
DR   PDB; 217L; X-ray; 1.70 A; A=1-164.
DR   PDB; 218L; X-ray; 2.05 A; A=1-164.
DR   PDB; 219L; X-ray; 1.66 A; A=1-164.
DR   PDB; 220L; X-ray; 1.85 A; A=1-164.
DR   PDB; 221L; X-ray; 1.70 A; A=1-164.
DR   PDB; 222L; X-ray; 1.90 A; A=1-164.
DR   PDB; 223L; X-ray; 1.90 A; A=1-164.
DR   PDB; 224L; X-ray; 1.85 A; A=1-164.
DR   PDB; 225L; X-ray; 1.90 A; A=1-164.
DR   PDB; 226L; X-ray; 1.80 A; A=1-164.
DR   PDB; 227L; X-ray; 2.00 A; A=1-164.
DR   PDB; 228L; X-ray; 1.90 A; A=1-164.
DR   PDB; 229L; X-ray; 1.80 A; A=1-164.
DR   PDB; 230L; X-ray; 1.90 A; A=1-164.
DR   PDB; 231L; X-ray; 2.50 A; A=1-164.
DR   PDB; 232L; X-ray; 1.73 A; A=1-164.
DR   PDB; 233L; X-ray; 1.90 A; A=1-164.
DR   PDB; 234L; X-ray; 1.90 A; A=1-164.
DR   PDB; 235L; X-ray; 1.90 A; A=1-164.
DR   PDB; 236L; X-ray; 1.90 A; A=1-164.
DR   PDB; 237L; X-ray; 1.70 A; A=1-164.
DR   PDB; 238L; X-ray; 1.80 A; A=1-164.
DR   PDB; 239L; X-ray; 1.80 A; A=1-164.
DR   PDB; 240L; X-ray; 1.75 A; A=1-164.
DR   PDB; 241L; X-ray; 1.70 A; A=1-164.
DR   PDB; 242L; X-ray; 1.80 A; A=1-164.
DR   PDB; 243L; X-ray; 1.75 A; A=1-164.
DR   PDB; 244L; X-ray; 1.70 A; A=1-164.
DR   PDB; 245L; X-ray; 1.80 A; A=1-164.
DR   PDB; 246L; X-ray; 1.80 A; A=1-164.
DR   PDB; 247L; X-ray; 1.75 A; A=1-164.
DR   PDB; 248L; X-ray; 1.90 A; A=1-164.
DR   PDB; 249L; X-ray; 1.90 A; A=1-164.
DR   PDB; 250L; X-ray; 1.80 A; A=1-164.
DR   PDB; 251L; X-ray; 2.60 A; A=1-164.
DR   PDB; 252L; X-ray; 2.10 A; A=1-164.
DR   PDB; 253L; X-ray; 2.00 A; A=1-164.
DR   PDB; 254L; X-ray; 1.90 A; A=1-164.
DR   PDB; 255L; X-ray; 1.80 A; A=1-164.
DR   PDB; 256L; X-ray; 1.80 A; A=1-164.
DR   PDB; 257L; X-ray; 1.90 A; A=1-164.
DR   PDB; 258L; X-ray; 1.80 A; A=1-164.
DR   PDB; 259L; X-ray; 1.92 A; A=1-164.
DR   PDB; 260L; X-ray; 1.80 A; A=1-164.
DR   PDB; 261L; X-ray; 2.50 A; A=1-162.
DR   PDB; 262L; X-ray; 2.50 A; A/B=1-162.
DR   PDB; 2A4T; X-ray; 1.70 A; A=1-164.
DR   PDB; 2B6T; X-ray; 2.10 A; A=1-162.
DR   PDB; 2B6W; X-ray; 2.20 A; A=1-162.
DR   PDB; 2B6X; X-ray; 2.11 A; A=1-162.
DR   PDB; 2B6Y; X-ray; 2.40 A; A=1-162.
DR   PDB; 2B6Z; X-ray; 2.40 A; A=1-162.
DR   PDB; 2B70; X-ray; 2.40 A; A=1-162.
DR   PDB; 2B72; X-ray; 2.10 A; A=1-162.
DR   PDB; 2B73; X-ray; 2.15 A; A=1-162.
DR   PDB; 2B74; X-ray; 2.10 A; A=1-162.
DR   PDB; 2B75; X-ray; 2.10 A; A=1-162.
DR   PDB; 2B7X; X-ray; 3.00 A; A/B/C/D=1-164.
DR   PDB; 2CUU; X-ray; 1.75 A; A=1-164.
DR   PDB; 2F2Q; X-ray; 1.45 A; A=1-164.
DR   PDB; 2F32; X-ray; 1.80 A; A=1-164.
DR   PDB; 2F47; X-ray; 1.70 A; A=1-164.
DR   PDB; 2HUK; X-ray; 2.00 A; A=1-164.
DR   PDB; 2HUL; X-ray; 1.80 A; A=1-164.
DR   PDB; 2HUM; X-ray; 2.35 A; A/B=1-164.
DR   PDB; 2IGC; X-ray; 1.40 A; A=1-164.
DR   PDB; 2L78; X-ray; 2.00 A; A=1-164.
DR   PDB; 2LC9; NMR; -; A=1-164.
DR   PDB; 2LCB; NMR; -; A=1-164.
DR   PDB; 2LZM; X-ray; 1.70 A; A=1-164.
DR   PDB; 2NTG; X-ray; 1.40 A; A=1-164.
DR   PDB; 2NTH; X-ray; 1.80 A; A=1-164.
DR   PDB; 2O4W; X-ray; 1.90 A; A=13-164.
DR   PDB; 2O79; X-ray; 1.80 A; A=1-164.
DR   PDB; 2O7A; X-ray; 0.84 A; A=60-164.
DR   PDB; 2OE4; X-ray; 2.10 A; X=1-164.
DR   PDB; 2OE7; X-ray; 2.10 A; X=1-164.
DR   PDB; 2OE9; X-ray; 2.01 A; X=1-164.
DR   PDB; 2OEA; X-ray; 2.01 A; X=1-164.
DR   PDB; 2OTY; X-ray; 1.83 A; X=1-162.
DR   PDB; 2OTZ; X-ray; 2.07 A; X=1-162.
DR   PDB; 2OU0; X-ray; 1.94 A; X=1-162.
DR   PDB; 2OU8; X-ray; 1.80 A; A=1-164.
DR   PDB; 2OU9; X-ray; 1.55 A; A=1-164.
DR   PDB; 2Q9D; X-ray; 1.40 A; A=1-164.
DR   PDB; 2Q9E; X-ray; 2.10 A; A/B/C=1-164.
DR   PDB; 2QAR; X-ray; 2.40 A; C/F=2-162.
DR   PDB; 2QB0; X-ray; 2.56 A; B/D=2-162.
DR   PDB; 2RAY; X-ray; 1.80 A; X=1-162.
DR   PDB; 2RAZ; X-ray; 1.64 A; X=1-162.
DR   PDB; 2RB0; X-ray; 1.84 A; X=1-162.
DR   PDB; 2RB1; X-ray; 1.70 A; X=1-162.
DR   PDB; 2RB2; X-ray; 1.46 A; X=1-162.
DR   PDB; 2RBN; X-ray; 1.29 A; A=1-162.
DR   PDB; 2RBO; X-ray; 1.29 A; A=1-162.
DR   PDB; 2RBP; X-ray; 1.47 A; A=1-162.
DR   PDB; 2RBQ; X-ray; 1.63 A; A=1-162.
DR   PDB; 2RBR; X-ray; 1.43 A; A=1-162.
DR   PDB; 2RBS; X-ray; 1.56 A; A=1-162.
DR   PDB; 2RH1; X-ray; 2.40 A; A=2-161.
DR   PDB; 3C7W; X-ray; 1.77 A; A=1-164.
DR   PDB; 3C7Y; X-ray; 1.95 A; A=1-164.
DR   PDB; 3C7Z; X-ray; 1.67 A; A=1-164.
DR   PDB; 3C80; X-ray; 1.99 A; A=1-164.
DR   PDB; 3C81; X-ray; 1.85 A; A=1-164.
DR   PDB; 3C82; X-ray; 1.68 A; A=1-164.
DR   PDB; 3C83; X-ray; 1.84 A; A=1-164.
DR   PDB; 3C8Q; X-ray; 1.64 A; A=1-164.
DR   PDB; 3C8R; X-ray; 1.80 A; A=1-164.
DR   PDB; 3C8S; X-ray; 1.68 A; A=1-164.
DR   PDB; 3CDO; X-ray; 1.87 A; A/B/C/D=1-164.
DR   PDB; 3CDQ; X-ray; 1.68 A; A=1-164.
DR   PDB; 3CDR; X-ray; 1.70 A; A=1-164.
DR   PDB; 3CDT; X-ray; 1.63 A; A=1-164.
DR   PDB; 3CDV; X-ray; 1.73 A; A=1-164.
DR   PDB; 3D4S; X-ray; 2.80 A; A=2-161.
DR   PDB; 3DKE; X-ray; 1.25 A; X=1-164.
DR   PDB; 3DMV; X-ray; 1.65 A; A=1-164.
DR   PDB; 3DMX; X-ray; 1.80 A; A=1-164.
DR   PDB; 3DMZ; X-ray; 2.00 A; A=1-164.
DR   PDB; 3DN0; X-ray; 1.80 A; A=1-164.
DR   PDB; 3DN1; X-ray; 1.80 A; A=1-164.
DR   PDB; 3DN2; X-ray; 1.80 A; A=1-164.
DR   PDB; 3DN3; X-ray; 1.80 A; A=1-164.
DR   PDB; 3DN4; X-ray; 1.80 A; A=1-164.
DR   PDB; 3DN6; X-ray; 1.80 A; A=1-164.
DR   PDB; 3DN8; X-ray; 1.70 A; A=1-164.
DR   PDB; 3DNA; X-ray; 1.70 A; A=1-164.
DR   PDB; 3EML; X-ray; 2.60 A; A=2-161.
DR   PDB; 3F8V; X-ray; 1.08 A; A=1-164.
DR   PDB; 3F9L; X-ray; 1.19 A; A=1-164.
DR   PDB; 3FA0; X-ray; 1.09 A; A=1-162.
DR   PDB; 3FAD; X-ray; 1.20 A; A=1-164.
DR   PDB; 3FI5; X-ray; 1.53 A; A/B/C/D=1-164.
DR   PDB; 3G3V; X-ray; 2.10 A; A=1-164.
DR   PDB; 3G3W; X-ray; 2.30 A; A=1-164.
DR   PDB; 3G3X; X-ray; 1.80 A; A=1-164.
DR   PDB; 3GUI; X-ray; 1.45 A; A=1-164.
DR   PDB; 3GUJ; X-ray; 1.60 A; A=1-164.
DR   PDB; 3GUK; X-ray; 1.85 A; A/B=1-164.
DR   PDB; 3GUL; X-ray; 2.07 A; A/B=1-164.
DR   PDB; 3GUM; X-ray; 2.24 A; A/B=1-164.
DR   PDB; 3GUN; X-ray; 1.50 A; A/B=1-164.
DR   PDB; 3GUO; X-ray; 2.16 A; A/B=1-164.
DR   PDB; 3GUP; X-ray; 1.50 A; A/B=1-164.
DR   PDB; 3HH3; X-ray; 1.25 A; A=1-164.
DR   PDB; 3HH4; X-ray; 1.25 A; A=1-164.
DR   PDB; 3HH5; X-ray; 1.25 A; A=1-164.
DR   PDB; 3HH6; X-ray; 1.25 A; A=1-164.
DR   PDB; 3HT6; X-ray; 1.59 A; A=1-164.
DR   PDB; 3HT7; X-ray; 1.70 A; A=1-164.
DR   PDB; 3HT8; X-ray; 1.60 A; A=1-164.
DR   PDB; 3HT9; X-ray; 2.02 A; A=1-164.
DR   PDB; 3HTB; X-ray; 1.81 A; A=1-164.
DR   PDB; 3HTD; X-ray; 1.40 A; A=1-164.
DR   PDB; 3HTF; X-ray; 1.85 A; A=1-164.
DR   PDB; 3HTG; X-ray; 1.26 A; A=1-164.
DR   PDB; 3HU8; X-ray; 1.80 A; A=1-164.
DR   PDB; 3HU9; X-ray; 1.46 A; A=1-164.
DR   PDB; 3HUA; X-ray; 1.40 A; A=1-164.
DR   PDB; 3HUK; X-ray; 1.29 A; A=1-164.
DR   PDB; 3HUQ; X-ray; 1.45 A; A=1-162.
DR   PDB; 3HWL; X-ray; 1.80 A; A=1-164.
DR   PDB; 3JR6; X-ray; 3.00 A; A/B/C/D=1-164.
DR   PDB; 3K2R; X-ray; 1.50 A; A=1-164.
DR   PDB; 3L2X; X-ray; 1.80 A; A=1-164.
DR   PDB; 3L64; X-ray; 1.90 A; A=1-164.
DR   PDB; 3LZM; X-ray; 1.70 A; A=1-164.
DR   PDB; 3NY8; X-ray; 2.84 A; A=2-161.
DR   PDB; 3NY9; X-ray; 2.84 A; A=2-161.
DR   PDB; 3NYA; X-ray; 3.16 A; A=2-161.
DR   PDB; 3ODU; X-ray; 2.50 A; A/B=2-161.
DR   PDB; 3OE0; X-ray; 2.90 A; A=2-161.
DR   PDB; 3OE6; X-ray; 3.20 A; A=2-161.
DR   PDB; 3OE8; X-ray; 3.10 A; A/B/C=2-161.
DR   PDB; 3OE9; X-ray; 3.10 A; A/B=2-161.
DR   PDB; 3P0G; X-ray; 3.50 A; A=2-161.
DR   PDB; 3PBL; X-ray; 2.89 A; A/B=2-161.
DR   PDB; 3PDS; X-ray; 3.50 A; A=2-162.
DR   PDB; 3QAK; X-ray; 2.71 A; A=2-161.
DR   PDB; 3RUN; X-ray; 1.40 A; A=1-164.
DR   PDB; 3RZE; X-ray; 3.10 A; A=2-161.
DR   PDB; 3SB5; X-ray; 2.46 A; A/B/C/D=1-162.
DR   PDB; 3SB6; X-ray; 2.70 A; A/B=1-162.
DR   PDB; 3SB7; X-ray; 2.70 A; A/B=1-162.
DR   PDB; 3SB8; X-ray; 2.65 A; A/B/C=1-162.
DR   PDB; 3SB9; X-ray; 2.45 A; A/B=1-162.
DR   PDB; 3SBA; X-ray; 2.75 A; A/B/C/D/E/F=1-162.
DR   PDB; 3SBB; X-ray; 1.43 A; C=1-162.
DR   PDB; 3SN6; X-ray; 3.20 A; R=2-161.
DR   PDB; 3UON; X-ray; 3.00 A; A=2-161.
DR   PDB; 3V2W; X-ray; 3.35 A; A=2-161.
DR   PDB; 3V2Y; X-ray; 2.80 A; A=2-161.
DR   PDB; 3VW7; X-ray; 2.20 A; A=2-161.
DR   PDB; 4ARJ; X-ray; 2.59 A; A/B=2-164.
DR   PDB; 4DAJ; X-ray; 3.40 A; A/B/C/D=1-161.
DR   PDB; 4DJH; X-ray; 2.90 A; A/B=2-161.
DR   PDB; 4DKL; X-ray; 2.80 A; A=2-161.
DR   PDB; 4E97; X-ray; 1.30 A; A/B=1-164.
DR   PDB; 4EJ4; X-ray; 3.40 A; A=2-161.
DR   PDB; 4EKP; X-ray; 1.64 A; A/B=1-164.
DR   PDB; 4EKQ; X-ray; 1.54 A; A/B=1-164.
DR   PDB; 4EKR; X-ray; 1.49 A; A/B=1-164.
DR   PDB; 4EKS; X-ray; 1.64 A; A/B=1-164.
DR   PDB; 4EPI; X-ray; 1.74 A; A=3-164.
DR   PDB; 4EXM; X-ray; 2.60 A; A/B/C/D=3-164.
DR   PDB; 4GBR; X-ray; 3.99 A; B=2-161.
DR   PDB; 4GRV; X-ray; 2.80 A; A=2-161.
DR   PDB; 4HTT; X-ray; 6.80 A; A/B=1-164.
DR   PDB; 4I7J; X-ray; 1.67 A; A/B=1-164.
DR   PDB; 4I7K; X-ray; 1.72 A; A/B=1-164.
DR   PDB; 4I7L; X-ray; 1.52 A; A/B=1-164.
DR   PDB; 4I7M; X-ray; 1.48 A; A/B=1-164.
DR   PDB; 4I7N; X-ray; 1.58 A; A/B=1-164.
DR   PDB; 4I7O; X-ray; 1.73 A; A/B=1-164.
DR   PDB; 4I7P; X-ray; 1.60 A; A/B=1-164.
DR   PDB; 4I7Q; X-ray; 1.58 A; A/B=1-164.
DR   PDB; 4I7R; X-ray; 1.52 A; A/B=1-164.
DR   PDB; 4I7S; X-ray; 1.69 A; A/B=1-164.
DR   PDB; 4I7T; X-ray; 1.55 A; A/B=1-164.
DR   PDB; 4IAP; X-ray; 2.30 A; A/B=2-161.
DR   PDB; 4K5Y; X-ray; 2.98 A; A/B/C=2-161.
DR   PDB; 4LDE; X-ray; 2.79 A; A=2-161.
DR   PDB; 4LDL; X-ray; 3.10 A; A=2-161.
DR   PDB; 4LDO; X-ray; 3.20 A; A=2-161.
DR   PDB; 4LZM; X-ray; 1.70 A; A=1-164.
DR   PDB; 4N9N; X-ray; 2.90 A; A/B=2-161.
DR   PDB; 4OO9; X-ray; 2.60 A; A=2-161.
DR   PDB; 4PHU; X-ray; 2.33 A; A=2-161.
DR   PDB; 4QKX; X-ray; 3.30 A; A=2-161.
DR   PDB; 4RWS; X-ray; 3.10 A; A=2-161.
DR   PDB; 4S0W; X-ray; 2.12 A; A/B=1-164.
DR   PDB; 4TN3; X-ray; 3.20 A; A/B=1-164.
DR   PDB; 4U14; X-ray; 3.57 A; A=1-161.
DR   PDB; 4W51; X-ray; 1.45 A; A=1-164.
DR   PDB; 4W52; X-ray; 1.50 A; A=1-164.
DR   PDB; 4W53; X-ray; 1.56 A; A=1-164.
DR   PDB; 4W54; X-ray; 1.79 A; A=1-164.
DR   PDB; 4W55; X-ray; 1.64 A; A=1-164.
DR   PDB; 4W56; X-ray; 1.63 A; A=1-164.
DR   PDB; 4W57; X-ray; 1.68 A; A=1-164.
DR   PDB; 4W58; X-ray; 1.80 A; A=1-164.
DR   PDB; 4W59; X-ray; 1.39 A; A=1-164.
DR   PDB; 4W8F; X-ray; 3.54 A; A/B=2-161.
DR   PDB; 4WTV; X-ray; 1.90 A; A/B=2-164.
DR   PDB; 4XEE; X-ray; 2.90 A; A=2-161.
DR   PDB; 4XES; X-ray; 2.60 A; A=2-161.
DR   PDB; 4YX7; X-ray; 2.00 A; C/F=2-164.
DR   PDB; 4YXA; X-ray; 2.35 A; C/F=2-164.
DR   PDB; 4YXC; X-ray; 2.30 A; A=2-161.
DR   PDB; 4ZWJ; X-ray; 3.30 A; A/B/C/D=2-161.
DR   PDB; 5B2G; X-ray; 3.50 A; A/C/E/G=2-162.
DR   PDB; 5CGC; X-ray; 3.10 A; A=2-161.
DR   PDB; 5CGD; X-ray; 2.60 A; A=2-161.
DR   PDB; 5CXV; X-ray; 2.70 A; A=2-161.
DR   PDB; 5D5A; X-ray; 2.48 A; A=2-161.
DR   PDB; 5D5B; X-ray; 3.80 A; A=2-161.
DR   PDB; 5D6L; X-ray; 3.20 A; A=2-162.
DR   PDB; 5DGY; X-ray; 7.70 A; A/B/C/D=2-161.
DR   PDB; 5DSG; X-ray; 2.60 A; A/B=61-161.
DR   PDB; 5EE7; X-ray; 2.50 A; A=2-160.
DR   PDB; 5EUT; X-ray; 2.80 A; A=2-163.
DR   PDB; 5EWX; X-ray; 2.60 A; A/B=1-35, A/B=38-164.
DR   PDB; 5G27; X-ray; 1.61 A; A=1-164.
DR   PDB; 5GLH; X-ray; 2.80 A; A=2-163.
DR   PDB; 5GLI; X-ray; 2.50 A; A=61-163.
DR   PDB; 5I14; X-ray; 1.75 A; A/B=1-11, A/B=61-164.
DR   PDB; 5JDT; X-ray; 1.00 A; A=1-164.
DR   PDB; 5JEA; X-ray; 2.65 A; K=1-164.
DR   PDB; 5JGN; X-ray; 1.53 A; A=1-164.
DR   PDB; 5JGR; X-ray; 1.46 A; A=1-164.
DR   PDB; 5JGU; X-ray; 1.47 A; A=1-164.
DR   PDB; 5JGV; X-ray; 1.73 A; A=1-164.
DR   PDB; 5JGX; X-ray; 1.53 A; A=1-164.
DR   PDB; 5JGZ; X-ray; 1.53 A; A=1-164.
DR   PDB; 5JQH; X-ray; 3.20 A; A/B=2-161.
DR   PDB; 5JWS; X-ray; 1.65 A; A=1-164.
DR   PDB; 5JWT; X-ray; 1.41 A; A=1-164.
DR   PDB; 5JWU; X-ray; 1.70 A; A=1-164.
DR   PDB; 5JWV; X-ray; 1.30 A; A=1-164.
DR   PDB; 5JWW; X-ray; 1.47 A; A=1-164.
DR   PDB; 5KGR; X-ray; 1.47 A; A=1-164.
DR   PDB; 5KHZ; X-ray; 1.49 A; A=1-164.
DR   PDB; 5KI1; X-ray; 1.46 A; A=1-164.
DR   PDB; 5KI2; X-ray; 1.50 A; A=1-164.
DR   PDB; 5KI3; X-ray; 1.65 A; A=1-164.
DR   PDB; 5KI8; X-ray; 1.55 A; A=1-164.
DR   PDB; 5KIG; X-ray; 1.50 A; A=1-164.
DR   PDB; 5KII; X-ray; 1.56 A; A=1-164.
DR   PDB; 5KIM; X-ray; 1.50 A; A=1-164.
DR   PDB; 5KIO; X-ray; 1.63 A; A=1-164.
DR   PDB; 5KW2; X-ray; 2.76 A; A=2-161.
DR   PDB; 5LWO; X-ray; 1.18 A; A=1-164.
DR   PDB; 5LZM; X-ray; 1.80 A; A=1-164.
DR   PDB; 5NDD; X-ray; 2.80 A; A=2-161.
DR   PDB; 5NDZ; X-ray; 3.60 A; A=2-161.
DR   PDB; 5T04; X-ray; 3.30 A; A=2-161.
DR   PDB; 5T1A; X-ray; 2.81 A; A=3-163.
DR   PDB; 5TZR; X-ray; 2.20 A; A=2-161.
DR   PDB; 5TZY; X-ray; 3.22 A; A=2-161.
DR   PDB; 5V7D; X-ray; 1.35 A; A=1-164.
DR   PDB; 5V7E; X-ray; 1.36 A; A=1-164.
DR   PDB; 5V7F; X-ray; 1.65 A; A=1-164.
DR   PDB; 5V83; X-ray; 2.00 A; A=1-164.
DR   PDB; 5V86; X-ray; 1.37 A; A=1-164.
DR   PDB; 5V88; X-ray; 1.60 A; A=1-164.
DR   PDB; 5VBA; X-ray; 2.27 A; A/B=2-162.
DR   PDB; 5VEW; X-ray; 2.70 A; A/B=5-161.
DR   PDB; 5VEX; X-ray; 3.00 A; A/B=5-161.
DR   PDB; 5VNQ; Neutron; 2.20 A; A=1-164.
DR   PDB; 5VNR; X-ray; 1.63 A; A=1-164.
DR   PDB; 5WF5; X-ray; 2.60 A; A=2-161.
DR   PDB; 5WF6; X-ray; 2.90 A; A=2-161.
DR   PDB; 5X7D; X-ray; 2.70 A; A=2-162.
DR   PDB; 5X93; X-ray; 2.20 A; A=61-161.
DR   PDB; 5XEZ; X-ray; 3.00 A; A/B=4-162.
DR   PDB; 5XF1; X-ray; 3.19 A; A/B=4-162.
DR   PDB; 5XPE; Other; 1.65 A; A=1-164.
DR   PDB; 5XPF; X-ray; 1.04 A; A=1-164.
DR   PDB; 5XPR; X-ray; 3.60 A; A=61-161.
DR   PDB; 5XSZ; X-ray; 3.20 A; A=2-161.
DR   PDB; 5YQR; X-ray; 2.40 A; A=2-161.
DR   PDB; 5YQZ; X-ray; 3.00 A; R=2-161.
DR   PDB; 5ZBH; X-ray; 3.00 A; A=3-161.
DR   PDB; 5ZBQ; X-ray; 2.70 A; A=1-161.
DR   PDB; 5ZHP; X-ray; 3.10 A; A/B=61-161.
DR   PDB; 5ZKQ; X-ray; 2.90 A; A/B=61-161.
DR   PDB; 6A73; X-ray; 2.45 A; A/B=2-164.
DR   PDB; 6A9E; X-ray; 3.21 A; A/B=1-161.
DR   PDB; 6A9J; X-ray; 2.70 A; A/B=1-161.
DR   PDB; 6BG3; X-ray; 1.05 A; A=1-164.
DR   PDB; 6BG5; X-ray; 1.10 A; A=1-164.
DR   PDB; 6CM4; X-ray; 2.87 A; A=2-162.
DR   PDB; 6D26; X-ray; 2.80 A; A=61-161.
DR   PDB; 6D27; X-ray; 2.74 A; A=61-161.
DR   PDB; 6D9M; X-ray; 1.35 A; A=1-161.
DR   PDB; 6FFH; X-ray; 2.65 A; A=2-162.
DR   PDB; 6FFI; X-ray; 2.20 A; A=2-162.
DR   PDB; 6IIH; X-ray; 1.96 A; A/B=1-161.
DR   PDB; 6J20; X-ray; 2.70 A; A=61-161.
DR   PDB; 6J21; X-ray; 3.20 A; A=61-161.
DR   PDB; 6K1Q; X-ray; 2.70 A; A=61-161.
DR   PDB; 6K69; X-ray; 2.40 A; B=1-164.
DR   PDB; 6KJV; X-ray; 2.80 A; A/B=2-161.
DR   PDB; 6KK1; X-ray; 2.80 A; A/B=2-161.
DR   PDB; 6KK7; X-ray; 3.10 A; A/B=2-161.
DR   PDB; 6KPC; X-ray; 3.20 A; A=2-161.
DR   PDB; 6LZM; X-ray; 1.80 A; A=1-164.
DR   PDB; 6M9T; X-ray; 2.50 A; A=2-161.
DR   PDB; 6MXT; X-ray; 2.96 A; A=2-161.
DR   PDB; 6QAJ; X-ray; 2.90 A; A/B=2-161.
DR   PDB; 6U0B; Other; 1.95 A; A=1-164.
DR   PDB; 6U0C; Other; 2.00 A; A=1-164.
DR   PDB; 6U0F; Other; 2.05 A; A=1-164.
DR   PDB; 6WSK; X-ray; 1.55 A; A=1-161.
DR   PDB; 6XYR; X-ray; 2.08 A; A=2-164.
DR   PDB; 6ZFZ; X-ray; 2.17 A; A=2-161.
DR   PDB; 6ZG4; X-ray; 2.33 A; A=2-161.
DR   PDB; 6ZG9; X-ray; 2.50 A; A=2-161.
DR   PDB; 6ZX9; X-ray; 2.52 A; C=2-164.
DR   PDB; 7DWS; X-ray; 2.80 A; A/B/C=1-162.
DR   PDB; 7F8U; X-ray; 2.80 A; A=2-161.
DR   PDB; 7F8X; X-ray; 3.00 A; A=2-161.
DR   PDB; 7F8Y; X-ray; 2.50 A; A=2-161.
DR   PDB; 7L37; X-ray; 1.44 A; A=1-164.
DR   PDB; 7L38; X-ray; 1.33 A; A=1-164.
DR   PDB; 7L39; X-ray; 1.35 A; A=1-164.
DR   PDB; 7L3A; X-ray; 1.11 A; A=1-164.
DR   PDB; 7L3B; X-ray; 1.27 A; A=1-164.
DR   PDB; 7L3C; X-ray; 1.31 A; A=1-164.
DR   PDB; 7L3D; X-ray; 1.35 A; A=1-164.
DR   PDB; 7L3E; X-ray; 1.13 A; A=1-164.
DR   PDB; 7L3F; X-ray; 1.49 A; A=1-164.
DR   PDB; 7L3G; X-ray; 1.27 A; A=1-164.
DR   PDB; 7L3H; X-ray; 1.39 A; A=1-164.
DR   PDB; 7L3I; X-ray; 1.46 A; A=1-164.
DR   PDB; 7L3J; X-ray; 1.49 A; A=1-164.
DR   PDB; 7L3K; X-ray; 1.11 A; A=1-164.
DR   PDB; 7LOA; X-ray; 1.07 A; A=1-164.
DR   PDB; 7LOB; X-ray; 1.10 A; A=1-164.
DR   PDB; 7LOC; X-ray; 1.16 A; A=1-164.
DR   PDB; 7LOD; X-ray; 1.02 A; A=1-164.
DR   PDB; 7LOE; X-ray; 1.01 A; A=1-164.
DR   PDB; 7LOF; X-ray; 1.05 A; A=1-164.
DR   PDB; 7LOJ; X-ray; 1.50 A; A=1-164.
DR   PDB; 7LX7; X-ray; 1.05 A; A=1-164.
DR   PDB; 7LX8; X-ray; 1.03 A; A=1-164.
DR   PDB; 7LX9; X-ray; 1.19 A; A=1-164.
DR   PDB; 7LZM; X-ray; 1.80 A; A=1-164.
DR   PDB; 7MI3; EM; 3.50 A; A=4-161.
DR   PDB; 7MI6; EM; 3.90 A; A=4-161.
DR   PDB; 7MI8; EM; 3.70 A; A=4-161.
DR   PDB; 7P2L; X-ray; 2.54 A; A=2-162.
DR   PDBsum; 102L; -.
DR   PDBsum; 103L; -.
DR   PDBsum; 104L; -.
DR   PDBsum; 107L; -.
DR   PDBsum; 108L; -.
DR   PDBsum; 109L; -.
DR   PDBsum; 110L; -.
DR   PDBsum; 111L; -.
DR   PDBsum; 112L; -.
DR   PDBsum; 113L; -.
DR   PDBsum; 114L; -.
DR   PDBsum; 115L; -.
DR   PDBsum; 118L; -.
DR   PDBsum; 119L; -.
DR   PDBsum; 120L; -.
DR   PDBsum; 122L; -.
DR   PDBsum; 123L; -.
DR   PDBsum; 125L; -.
DR   PDBsum; 126L; -.
DR   PDBsum; 127L; -.
DR   PDBsum; 128L; -.
DR   PDBsum; 129L; -.
DR   PDBsum; 130L; -.
DR   PDBsum; 131L; -.
DR   PDBsum; 137L; -.
DR   PDBsum; 138L; -.
DR   PDBsum; 139L; -.
DR   PDBsum; 140L; -.
DR   PDBsum; 141L; -.
DR   PDBsum; 142L; -.
DR   PDBsum; 143L; -.
DR   PDBsum; 144L; -.
DR   PDBsum; 145L; -.
DR   PDBsum; 146L; -.
DR   PDBsum; 147L; -.
DR   PDBsum; 148L; -.
DR   PDBsum; 149L; -.
DR   PDBsum; 150L; -.
DR   PDBsum; 151L; -.
DR   PDBsum; 152L; -.
DR   PDBsum; 155L; -.
DR   PDBsum; 156L; -.
DR   PDBsum; 157L; -.
DR   PDBsum; 158L; -.
DR   PDBsum; 159L; -.
DR   PDBsum; 160L; -.
DR   PDBsum; 161L; -.
DR   PDBsum; 162L; -.
DR   PDBsum; 163L; -.
DR   PDBsum; 164L; -.
DR   PDBsum; 165L; -.
DR   PDBsum; 166L; -.
DR   PDBsum; 167L; -.
DR   PDBsum; 168L; -.
DR   PDBsum; 169L; -.
DR   PDBsum; 170L; -.
DR   PDBsum; 171L; -.
DR   PDBsum; 172L; -.
DR   PDBsum; 173L; -.
DR   PDBsum; 174L; -.
DR   PDBsum; 175L; -.
DR   PDBsum; 176L; -.
DR   PDBsum; 177L; -.
DR   PDBsum; 178L; -.
DR   PDBsum; 180L; -.
DR   PDBsum; 181L; -.
DR   PDBsum; 182L; -.
DR   PDBsum; 183L; -.
DR   PDBsum; 184L; -.
DR   PDBsum; 185L; -.
DR   PDBsum; 186L; -.
DR   PDBsum; 187L; -.
DR   PDBsum; 188L; -.
DR   PDBsum; 189L; -.
DR   PDBsum; 190L; -.
DR   PDBsum; 191L; -.
DR   PDBsum; 192L; -.
DR   PDBsum; 195L; -.
DR   PDBsum; 196L; -.
DR   PDBsum; 197L; -.
DR   PDBsum; 198L; -.
DR   PDBsum; 199L; -.
DR   PDBsum; 1B6I; -.
DR   PDBsum; 1C60; -.
DR   PDBsum; 1C61; -.
DR   PDBsum; 1C62; -.
DR   PDBsum; 1C63; -.
DR   PDBsum; 1C64; -.
DR   PDBsum; 1C65; -.
DR   PDBsum; 1C66; -.
DR   PDBsum; 1C67; -.
DR   PDBsum; 1C68; -.
DR   PDBsum; 1C69; -.
DR   PDBsum; 1C6A; -.
DR   PDBsum; 1C6B; -.
DR   PDBsum; 1C6C; -.
DR   PDBsum; 1C6D; -.
DR   PDBsum; 1C6E; -.
DR   PDBsum; 1C6F; -.
DR   PDBsum; 1C6G; -.
DR   PDBsum; 1C6H; -.
DR   PDBsum; 1C6I; -.
DR   PDBsum; 1C6J; -.
DR   PDBsum; 1C6K; -.
DR   PDBsum; 1C6L; -.
DR   PDBsum; 1C6M; -.
DR   PDBsum; 1C6N; -.
DR   PDBsum; 1C6P; -.
DR   PDBsum; 1C6Q; -.
DR   PDBsum; 1C6T; -.
DR   PDBsum; 1CTW; -.
DR   PDBsum; 1CU0; -.
DR   PDBsum; 1CU2; -.
DR   PDBsum; 1CU3; -.
DR   PDBsum; 1CU5; -.
DR   PDBsum; 1CU6; -.
DR   PDBsum; 1CUP; -.
DR   PDBsum; 1CUQ; -.
DR   PDBsum; 1CV0; -.
DR   PDBsum; 1CV1; -.
DR   PDBsum; 1CV3; -.
DR   PDBsum; 1CV4; -.
DR   PDBsum; 1CV5; -.
DR   PDBsum; 1CV6; -.
DR   PDBsum; 1CVK; -.
DR   PDBsum; 1CX6; -.
DR   PDBsum; 1CX7; -.
DR   PDBsum; 1D2W; -.
DR   PDBsum; 1D2Y; -.
DR   PDBsum; 1D3F; -.
DR   PDBsum; 1D3J; -.
DR   PDBsum; 1D3M; -.
DR   PDBsum; 1D3N; -.
DR   PDBsum; 1D9W; -.
DR   PDBsum; 1DYA; -.
DR   PDBsum; 1DYB; -.
DR   PDBsum; 1DYC; -.
DR   PDBsum; 1DYD; -.
DR   PDBsum; 1DYE; -.
DR   PDBsum; 1DYF; -.
DR   PDBsum; 1DYG; -.
DR   PDBsum; 1EPY; -.
DR   PDBsum; 1G06; -.
DR   PDBsum; 1G07; -.
DR   PDBsum; 1G0G; -.
DR   PDBsum; 1G0J; -.
DR   PDBsum; 1G0K; -.
DR   PDBsum; 1G0L; -.
DR   PDBsum; 1G0M; -.
DR   PDBsum; 1G0P; -.
DR   PDBsum; 1G0Q; -.
DR   PDBsum; 1G1V; -.
DR   PDBsum; 1G1W; -.
DR   PDBsum; 1I6S; -.
DR   PDBsum; 1JQU; -.
DR   PDBsum; 1JTM; -.
DR   PDBsum; 1JTN; -.
DR   PDBsum; 1KNI; -.
DR   PDBsum; 1KS3; -.
DR   PDBsum; 1KW5; -.
DR   PDBsum; 1KW7; -.
DR   PDBsum; 1KY0; -.
DR   PDBsum; 1KY1; -.
DR   PDBsum; 1L00; -.
DR   PDBsum; 1L01; -.
DR   PDBsum; 1L02; -.
DR   PDBsum; 1L03; -.
DR   PDBsum; 1L04; -.
DR   PDBsum; 1L05; -.
DR   PDBsum; 1L06; -.
DR   PDBsum; 1L07; -.
DR   PDBsum; 1L08; -.
DR   PDBsum; 1L09; -.
DR   PDBsum; 1L0J; -.
DR   PDBsum; 1L0K; -.
DR   PDBsum; 1L10; -.
DR   PDBsum; 1L11; -.
DR   PDBsum; 1L12; -.
DR   PDBsum; 1L13; -.
DR   PDBsum; 1L14; -.
DR   PDBsum; 1L15; -.
DR   PDBsum; 1L16; -.
DR   PDBsum; 1L17; -.
DR   PDBsum; 1L18; -.
DR   PDBsum; 1L19; -.
DR   PDBsum; 1L20; -.
DR   PDBsum; 1L21; -.
DR   PDBsum; 1L22; -.
DR   PDBsum; 1L23; -.
DR   PDBsum; 1L24; -.
DR   PDBsum; 1L25; -.
DR   PDBsum; 1L26; -.
DR   PDBsum; 1L27; -.
DR   PDBsum; 1L28; -.
DR   PDBsum; 1L29; -.
DR   PDBsum; 1L30; -.
DR   PDBsum; 1L31; -.
DR   PDBsum; 1L32; -.
DR   PDBsum; 1L33; -.
DR   PDBsum; 1L34; -.
DR   PDBsum; 1L35; -.
DR   PDBsum; 1L36; -.
DR   PDBsum; 1L37; -.
DR   PDBsum; 1L38; -.
DR   PDBsum; 1L39; -.
DR   PDBsum; 1L40; -.
DR   PDBsum; 1L41; -.
DR   PDBsum; 1L42; -.
DR   PDBsum; 1L43; -.
DR   PDBsum; 1L44; -.
DR   PDBsum; 1L45; -.
DR   PDBsum; 1L46; -.
DR   PDBsum; 1L47; -.
DR   PDBsum; 1L48; -.
DR   PDBsum; 1L49; -.
DR   PDBsum; 1L50; -.
DR   PDBsum; 1L51; -.
DR   PDBsum; 1L52; -.
DR   PDBsum; 1L53; -.
DR   PDBsum; 1L54; -.
DR   PDBsum; 1L55; -.
DR   PDBsum; 1L56; -.
DR   PDBsum; 1L57; -.
DR   PDBsum; 1L58; -.
DR   PDBsum; 1L59; -.
DR   PDBsum; 1L60; -.
DR   PDBsum; 1L61; -.
DR   PDBsum; 1L62; -.
DR   PDBsum; 1L63; -.
DR   PDBsum; 1L64; -.
DR   PDBsum; 1L65; -.
DR   PDBsum; 1L66; -.
DR   PDBsum; 1L67; -.
DR   PDBsum; 1L68; -.
DR   PDBsum; 1L69; -.
DR   PDBsum; 1L70; -.
DR   PDBsum; 1L71; -.
DR   PDBsum; 1L72; -.
DR   PDBsum; 1L73; -.
DR   PDBsum; 1L74; -.
DR   PDBsum; 1L75; -.
DR   PDBsum; 1L76; -.
DR   PDBsum; 1L77; -.
DR   PDBsum; 1L79; -.
DR   PDBsum; 1L80; -.
DR   PDBsum; 1L81; -.
DR   PDBsum; 1L82; -.
DR   PDBsum; 1L83; -.
DR   PDBsum; 1L84; -.
DR   PDBsum; 1L85; -.
DR   PDBsum; 1L86; -.
DR   PDBsum; 1L87; -.
DR   PDBsum; 1L88; -.
DR   PDBsum; 1L89; -.
DR   PDBsum; 1L90; -.
DR   PDBsum; 1L91; -.
DR   PDBsum; 1L92; -.
DR   PDBsum; 1L93; -.
DR   PDBsum; 1L94; -.
DR   PDBsum; 1L95; -.
DR   PDBsum; 1L96; -.
DR   PDBsum; 1L97; -.
DR   PDBsum; 1L98; -.
DR   PDBsum; 1L99; -.
DR   PDBsum; 1LGU; -.
DR   PDBsum; 1LGW; -.
DR   PDBsum; 1LGX; -.
DR   PDBsum; 1LI2; -.
DR   PDBsum; 1LI3; -.
DR   PDBsum; 1LI6; -.
DR   PDBsum; 1LLH; -.
DR   PDBsum; 1LPY; -.
DR   PDBsum; 1LW9; -.
DR   PDBsum; 1LWG; -.
DR   PDBsum; 1LWK; -.
DR   PDBsum; 1LYD; -.
DR   PDBsum; 1LYE; -.
DR   PDBsum; 1LYF; -.
DR   PDBsum; 1LYG; -.
DR   PDBsum; 1LYH; -.
DR   PDBsum; 1LYI; -.
DR   PDBsum; 1LYJ; -.
DR   PDBsum; 1NHB; -.
DR   PDBsum; 1OV5; -.
DR   PDBsum; 1OV7; -.
DR   PDBsum; 1OVH; -.
DR   PDBsum; 1OVJ; -.
DR   PDBsum; 1OVK; -.
DR   PDBsum; 1OWY; -.
DR   PDBsum; 1OWZ; -.
DR   PDBsum; 1OYU; -.
DR   PDBsum; 1P2L; -.
DR   PDBsum; 1P2R; -.
DR   PDBsum; 1P36; -.
DR   PDBsum; 1P37; -.
DR   PDBsum; 1P3N; -.
DR   PDBsum; 1P46; -.
DR   PDBsum; 1P56; -.
DR   PDBsum; 1P5C; -.
DR   PDBsum; 1P64; -.
DR   PDBsum; 1P6Y; -.
DR   PDBsum; 1P7S; -.
DR   PDBsum; 1PQD; -.
DR   PDBsum; 1PQI; -.
DR   PDBsum; 1PQJ; -.
DR   PDBsum; 1PQK; -.
DR   PDBsum; 1PQM; -.
DR   PDBsum; 1PQO; -.
DR   PDBsum; 1QS5; -.
DR   PDBsum; 1QS9; -.
DR   PDBsum; 1QSB; -.
DR   PDBsum; 1QSQ; -.
DR   PDBsum; 1QT3; -.
DR   PDBsum; 1QT4; -.
DR   PDBsum; 1QT5; -.
DR   PDBsum; 1QT6; -.
DR   PDBsum; 1QT7; -.
DR   PDBsum; 1QT8; -.
DR   PDBsum; 1QTB; -.
DR   PDBsum; 1QTC; -.
DR   PDBsum; 1QTD; -.
DR   PDBsum; 1QTH; -.
DR   PDBsum; 1QTV; -.
DR   PDBsum; 1QTZ; -.
DR   PDBsum; 1QUD; -.
DR   PDBsum; 1QUG; -.
DR   PDBsum; 1QUH; -.
DR   PDBsum; 1QUO; -.
DR   PDBsum; 1SSW; -.
DR   PDBsum; 1SSY; -.
DR   PDBsum; 1SWY; -.
DR   PDBsum; 1SWZ; -.
DR   PDBsum; 1SX2; -.
DR   PDBsum; 1SX7; -.
DR   PDBsum; 1T6H; -.
DR   PDBsum; 1T8A; -.
DR   PDBsum; 1T8F; -.
DR   PDBsum; 1T8G; -.
DR   PDBsum; 1T97; -.
DR   PDBsum; 1TLA; -.
DR   PDBsum; 1XEP; -.
DR   PDBsum; 1ZUR; -.
DR   PDBsum; 1ZWN; -.
DR   PDBsum; 1ZYT; -.
DR   PDBsum; 200L; -.
DR   PDBsum; 201L; -.
DR   PDBsum; 205L; -.
DR   PDBsum; 206L; -.
DR   PDBsum; 209L; -.
DR   PDBsum; 210L; -.
DR   PDBsum; 211L; -.
DR   PDBsum; 212L; -.
DR   PDBsum; 213L; -.
DR   PDBsum; 214L; -.
DR   PDBsum; 215L; -.
DR   PDBsum; 216L; -.
DR   PDBsum; 217L; -.
DR   PDBsum; 218L; -.
DR   PDBsum; 219L; -.
DR   PDBsum; 220L; -.
DR   PDBsum; 221L; -.
DR   PDBsum; 222L; -.
DR   PDBsum; 223L; -.
DR   PDBsum; 224L; -.
DR   PDBsum; 225L; -.
DR   PDBsum; 226L; -.
DR   PDBsum; 227L; -.
DR   PDBsum; 228L; -.
DR   PDBsum; 229L; -.
DR   PDBsum; 230L; -.
DR   PDBsum; 231L; -.
DR   PDBsum; 232L; -.
DR   PDBsum; 233L; -.
DR   PDBsum; 234L; -.
DR   PDBsum; 235L; -.
DR   PDBsum; 236L; -.
DR   PDBsum; 237L; -.
DR   PDBsum; 238L; -.
DR   PDBsum; 239L; -.
DR   PDBsum; 240L; -.
DR   PDBsum; 241L; -.
DR   PDBsum; 242L; -.
DR   PDBsum; 243L; -.
DR   PDBsum; 244L; -.
DR   PDBsum; 245L; -.
DR   PDBsum; 246L; -.
DR   PDBsum; 247L; -.
DR   PDBsum; 248L; -.
DR   PDBsum; 249L; -.
DR   PDBsum; 250L; -.
DR   PDBsum; 251L; -.
DR   PDBsum; 252L; -.
DR   PDBsum; 253L; -.
DR   PDBsum; 254L; -.
DR   PDBsum; 255L; -.
DR   PDBsum; 256L; -.
DR   PDBsum; 257L; -.
DR   PDBsum; 258L; -.
DR   PDBsum; 259L; -.
DR   PDBsum; 260L; -.
DR   PDBsum; 261L; -.
DR   PDBsum; 262L; -.
DR   PDBsum; 2A4T; -.
DR   PDBsum; 2B6T; -.
DR   PDBsum; 2B6W; -.
DR   PDBsum; 2B6X; -.
DR   PDBsum; 2B6Y; -.
DR   PDBsum; 2B6Z; -.
DR   PDBsum; 2B70; -.
DR   PDBsum; 2B72; -.
DR   PDBsum; 2B73; -.
DR   PDBsum; 2B74; -.
DR   PDBsum; 2B75; -.
DR   PDBsum; 2B7X; -.
DR   PDBsum; 2CUU; -.
DR   PDBsum; 2F2Q; -.
DR   PDBsum; 2F32; -.
DR   PDBsum; 2F47; -.
DR   PDBsum; 2HUK; -.
DR   PDBsum; 2HUL; -.
DR   PDBsum; 2HUM; -.
DR   PDBsum; 2IGC; -.
DR   PDBsum; 2L78; -.
DR   PDBsum; 2LC9; -.
DR   PDBsum; 2LCB; -.
DR   PDBsum; 2LZM; -.
DR   PDBsum; 2NTG; -.
DR   PDBsum; 2NTH; -.
DR   PDBsum; 2O4W; -.
DR   PDBsum; 2O79; -.
DR   PDBsum; 2O7A; -.
DR   PDBsum; 2OE4; -.
DR   PDBsum; 2OE7; -.
DR   PDBsum; 2OE9; -.
DR   PDBsum; 2OEA; -.
DR   PDBsum; 2OTY; -.
DR   PDBsum; 2OTZ; -.
DR   PDBsum; 2OU0; -.
DR   PDBsum; 2OU8; -.
DR   PDBsum; 2OU9; -.
DR   PDBsum; 2Q9D; -.
DR   PDBsum; 2Q9E; -.
DR   PDBsum; 2QAR; -.
DR   PDBsum; 2QB0; -.
DR   PDBsum; 2RAY; -.
DR   PDBsum; 2RAZ; -.
DR   PDBsum; 2RB0; -.
DR   PDBsum; 2RB1; -.
DR   PDBsum; 2RB2; -.
DR   PDBsum; 2RBN; -.
DR   PDBsum; 2RBO; -.
DR   PDBsum; 2RBP; -.
DR   PDBsum; 2RBQ; -.
DR   PDBsum; 2RBR; -.
DR   PDBsum; 2RBS; -.
DR   PDBsum; 2RH1; -.
DR   PDBsum; 3C7W; -.
DR   PDBsum; 3C7Y; -.
DR   PDBsum; 3C7Z; -.
DR   PDBsum; 3C80; -.
DR   PDBsum; 3C81; -.
DR   PDBsum; 3C82; -.
DR   PDBsum; 3C83; -.
DR   PDBsum; 3C8Q; -.
DR   PDBsum; 3C8R; -.
DR   PDBsum; 3C8S; -.
DR   PDBsum; 3CDO; -.
DR   PDBsum; 3CDQ; -.
DR   PDBsum; 3CDR; -.
DR   PDBsum; 3CDT; -.
DR   PDBsum; 3CDV; -.
DR   PDBsum; 3D4S; -.
DR   PDBsum; 3DKE; -.
DR   PDBsum; 3DMV; -.
DR   PDBsum; 3DMX; -.
DR   PDBsum; 3DMZ; -.
DR   PDBsum; 3DN0; -.
DR   PDBsum; 3DN1; -.
DR   PDBsum; 3DN2; -.
DR   PDBsum; 3DN3; -.
DR   PDBsum; 3DN4; -.
DR   PDBsum; 3DN6; -.
DR   PDBsum; 3DN8; -.
DR   PDBsum; 3DNA; -.
DR   PDBsum; 3EML; -.
DR   PDBsum; 3F8V; -.
DR   PDBsum; 3F9L; -.
DR   PDBsum; 3FA0; -.
DR   PDBsum; 3FAD; -.
DR   PDBsum; 3FI5; -.
DR   PDBsum; 3G3V; -.
DR   PDBsum; 3G3W; -.
DR   PDBsum; 3G3X; -.
DR   PDBsum; 3GUI; -.
DR   PDBsum; 3GUJ; -.
DR   PDBsum; 3GUK; -.
DR   PDBsum; 3GUL; -.
DR   PDBsum; 3GUM; -.
DR   PDBsum; 3GUN; -.
DR   PDBsum; 3GUO; -.
DR   PDBsum; 3GUP; -.
DR   PDBsum; 3HH3; -.
DR   PDBsum; 3HH4; -.
DR   PDBsum; 3HH5; -.
DR   PDBsum; 3HH6; -.
DR   PDBsum; 3HT6; -.
DR   PDBsum; 3HT7; -.
DR   PDBsum; 3HT8; -.
DR   PDBsum; 3HT9; -.
DR   PDBsum; 3HTB; -.
DR   PDBsum; 3HTD; -.
DR   PDBsum; 3HTF; -.
DR   PDBsum; 3HTG; -.
DR   PDBsum; 3HU8; -.
DR   PDBsum; 3HU9; -.
DR   PDBsum; 3HUA; -.
DR   PDBsum; 3HUK; -.
DR   PDBsum; 3HUQ; -.
DR   PDBsum; 3HWL; -.
DR   PDBsum; 3JR6; -.
DR   PDBsum; 3K2R; -.
DR   PDBsum; 3L2X; -.
DR   PDBsum; 3L64; -.
DR   PDBsum; 3LZM; -.
DR   PDBsum; 3NY8; -.
DR   PDBsum; 3NY9; -.
DR   PDBsum; 3NYA; -.
DR   PDBsum; 3ODU; -.
DR   PDBsum; 3OE0; -.
DR   PDBsum; 3OE6; -.
DR   PDBsum; 3OE8; -.
DR   PDBsum; 3OE9; -.
DR   PDBsum; 3P0G; -.
DR   PDBsum; 3PBL; -.
DR   PDBsum; 3PDS; -.
DR   PDBsum; 3QAK; -.
DR   PDBsum; 3RUN; -.
DR   PDBsum; 3RZE; -.
DR   PDBsum; 3SB5; -.
DR   PDBsum; 3SB6; -.
DR   PDBsum; 3SB7; -.
DR   PDBsum; 3SB8; -.
DR   PDBsum; 3SB9; -.
DR   PDBsum; 3SBA; -.
DR   PDBsum; 3SBB; -.
DR   PDBsum; 3SN6; -.
DR   PDBsum; 3UON; -.
DR   PDBsum; 3V2W; -.
DR   PDBsum; 3V2Y; -.
DR   PDBsum; 3VW7; -.
DR   PDBsum; 4ARJ; -.
DR   PDBsum; 4DAJ; -.
DR   PDBsum; 4DJH; -.
DR   PDBsum; 4DKL; -.
DR   PDBsum; 4E97; -.
DR   PDBsum; 4EJ4; -.
DR   PDBsum; 4EKP; -.
DR   PDBsum; 4EKQ; -.
DR   PDBsum; 4EKR; -.
DR   PDBsum; 4EKS; -.
DR   PDBsum; 4EPI; -.
DR   PDBsum; 4EXM; -.
DR   PDBsum; 4GBR; -.
DR   PDBsum; 4GRV; -.
DR   PDBsum; 4HTT; -.
DR   PDBsum; 4I7J; -.
DR   PDBsum; 4I7K; -.
DR   PDBsum; 4I7L; -.
DR   PDBsum; 4I7M; -.
DR   PDBsum; 4I7N; -.
DR   PDBsum; 4I7O; -.
DR   PDBsum; 4I7P; -.
DR   PDBsum; 4I7Q; -.
DR   PDBsum; 4I7R; -.
DR   PDBsum; 4I7S; -.
DR   PDBsum; 4I7T; -.
DR   PDBsum; 4IAP; -.
DR   PDBsum; 4K5Y; -.
DR   PDBsum; 4LDE; -.
DR   PDBsum; 4LDL; -.
DR   PDBsum; 4LDO; -.
DR   PDBsum; 4LZM; -.
DR   PDBsum; 4N9N; -.
DR   PDBsum; 4OO9; -.
DR   PDBsum; 4PHU; -.
DR   PDBsum; 4QKX; -.
DR   PDBsum; 4RWS; -.
DR   PDBsum; 4S0W; -.
DR   PDBsum; 4TN3; -.
DR   PDBsum; 4U14; -.
DR   PDBsum; 4W51; -.
DR   PDBsum; 4W52; -.
DR   PDBsum; 4W53; -.
DR   PDBsum; 4W54; -.
DR   PDBsum; 4W55; -.
DR   PDBsum; 4W56; -.
DR   PDBsum; 4W57; -.
DR   PDBsum; 4W58; -.
DR   PDBsum; 4W59; -.
DR   PDBsum; 4W8F; -.
DR   PDBsum; 4WTV; -.
DR   PDBsum; 4XEE; -.
DR   PDBsum; 4XES; -.
DR   PDBsum; 4YX7; -.
DR   PDBsum; 4YXA; -.
DR   PDBsum; 4YXC; -.
DR   PDBsum; 4ZWJ; -.
DR   PDBsum; 5B2G; -.
DR   PDBsum; 5CGC; -.
DR   PDBsum; 5CGD; -.
DR   PDBsum; 5CXV; -.
DR   PDBsum; 5D5A; -.
DR   PDBsum; 5D5B; -.
DR   PDBsum; 5D6L; -.
DR   PDBsum; 5DGY; -.
DR   PDBsum; 5DSG; -.
DR   PDBsum; 5EE7; -.
DR   PDBsum; 5EUT; -.
DR   PDBsum; 5EWX; -.
DR   PDBsum; 5G27; -.
DR   PDBsum; 5GLH; -.
DR   PDBsum; 5GLI; -.
DR   PDBsum; 5I14; -.
DR   PDBsum; 5JDT; -.
DR   PDBsum; 5JEA; -.
DR   PDBsum; 5JGN; -.
DR   PDBsum; 5JGR; -.
DR   PDBsum; 5JGU; -.
DR   PDBsum; 5JGV; -.
DR   PDBsum; 5JGX; -.
DR   PDBsum; 5JGZ; -.
DR   PDBsum; 5JQH; -.
DR   PDBsum; 5JWS; -.
DR   PDBsum; 5JWT; -.
DR   PDBsum; 5JWU; -.
DR   PDBsum; 5JWV; -.
DR   PDBsum; 5JWW; -.
DR   PDBsum; 5KGR; -.
DR   PDBsum; 5KHZ; -.
DR   PDBsum; 5KI1; -.
DR   PDBsum; 5KI2; -.
DR   PDBsum; 5KI3; -.
DR   PDBsum; 5KI8; -.
DR   PDBsum; 5KIG; -.
DR   PDBsum; 5KII; -.
DR   PDBsum; 5KIM; -.
DR   PDBsum; 5KIO; -.
DR   PDBsum; 5KW2; -.
DR   PDBsum; 5LWO; -.
DR   PDBsum; 5LZM; -.
DR   PDBsum; 5NDD; -.
DR   PDBsum; 5NDZ; -.
DR   PDBsum; 5T04; -.
DR   PDBsum; 5T1A; -.
DR   PDBsum; 5TZR; -.
DR   PDBsum; 5TZY; -.
DR   PDBsum; 5V7D; -.
DR   PDBsum; 5V7E; -.
DR   PDBsum; 5V7F; -.
DR   PDBsum; 5V83; -.
DR   PDBsum; 5V86; -.
DR   PDBsum; 5V88; -.
DR   PDBsum; 5VBA; -.
DR   PDBsum; 5VEW; -.
DR   PDBsum; 5VEX; -.
DR   PDBsum; 5VNQ; -.
DR   PDBsum; 5VNR; -.
DR   PDBsum; 5WF5; -.
DR   PDBsum; 5WF6; -.
DR   PDBsum; 5X7D; -.
DR   PDBsum; 5X93; -.
DR   PDBsum; 5XEZ; -.
DR   PDBsum; 5XF1; -.
DR   PDBsum; 5XPE; -.
DR   PDBsum; 5XPF; -.
DR   PDBsum; 5XPR; -.
DR   PDBsum; 5XSZ; -.
DR   PDBsum; 5YQR; -.
DR   PDBsum; 5YQZ; -.
DR   PDBsum; 5ZBH; -.
DR   PDBsum; 5ZBQ; -.
DR   PDBsum; 5ZHP; -.
DR   PDBsum; 5ZKQ; -.
DR   PDBsum; 6A73; -.
DR   PDBsum; 6A9E; -.
DR   PDBsum; 6A9J; -.
DR   PDBsum; 6BG3; -.
DR   PDBsum; 6BG5; -.
DR   PDBsum; 6CM4; -.
DR   PDBsum; 6D26; -.
DR   PDBsum; 6D27; -.
DR   PDBsum; 6D9M; -.
DR   PDBsum; 6FFH; -.
DR   PDBsum; 6FFI; -.
DR   PDBsum; 6IIH; -.
DR   PDBsum; 6J20; -.
DR   PDBsum; 6J21; -.
DR   PDBsum; 6K1Q; -.
DR   PDBsum; 6K69; -.
DR   PDBsum; 6KJV; -.
DR   PDBsum; 6KK1; -.
DR   PDBsum; 6KK7; -.
DR   PDBsum; 6KPC; -.
DR   PDBsum; 6LZM; -.
DR   PDBsum; 6M9T; -.
DR   PDBsum; 6MXT; -.
DR   PDBsum; 6QAJ; -.
DR   PDBsum; 6U0B; -.
DR   PDBsum; 6U0C; -.
DR   PDBsum; 6U0F; -.
DR   PDBsum; 6WSK; -.
DR   PDBsum; 6XYR; -.
DR   PDBsum; 6ZFZ; -.
DR   PDBsum; 6ZG4; -.
DR   PDBsum; 6ZG9; -.
DR   PDBsum; 6ZX9; -.
DR   PDBsum; 7DWS; -.
DR   PDBsum; 7F8U; -.
DR   PDBsum; 7F8X; -.
DR   PDBsum; 7F8Y; -.
DR   PDBsum; 7L37; -.
DR   PDBsum; 7L38; -.
DR   PDBsum; 7L39; -.
DR   PDBsum; 7L3A; -.
DR   PDBsum; 7L3B; -.
DR   PDBsum; 7L3C; -.
DR   PDBsum; 7L3D; -.
DR   PDBsum; 7L3E; -.
DR   PDBsum; 7L3F; -.
DR   PDBsum; 7L3G; -.
DR   PDBsum; 7L3H; -.
DR   PDBsum; 7L3I; -.
DR   PDBsum; 7L3J; -.
DR   PDBsum; 7L3K; -.
DR   PDBsum; 7LOA; -.
DR   PDBsum; 7LOB; -.
DR   PDBsum; 7LOC; -.
DR   PDBsum; 7LOD; -.
DR   PDBsum; 7LOE; -.
DR   PDBsum; 7LOF; -.
DR   PDBsum; 7LOJ; -.
DR   PDBsum; 7LX7; -.
DR   PDBsum; 7LX8; -.
DR   PDBsum; 7LX9; -.
DR   PDBsum; 7LZM; -.
DR   PDBsum; 7MI3; -.
DR   PDBsum; 7MI6; -.
DR   PDBsum; 7MI8; -.
DR   PDBsum; 7P2L; -.
DR   BMRB; P00720; -.
DR   SMR; P00720; -.
DR   BindingDB; P00720; -.
DR   ChEMBL; CHEMBL5206; -.
DR   DrugBank; DB06934; (1R)-3-chloro-1-phenylpropan-1-ol.
DR   DrugBank; DB07543; (S)-carazolol.
DR   DrugBank; DB03301; 2-Allyl-6-Methyl-Phenol.
DR   DrugBank; DB02534; 2-Allylphenol.
DR   DrugBank; DB03842; 2-Chloro-6-Methyl-Aniline.
DR   DrugBank; DB02403; 2-Fluoroaniline.
DR   DrugBank; DB02486; 2-Hydroxyethyl Disulfide.
DR   DrugBank; DB02970; 2-Propyl-Aniline.
DR   DrugBank; DB03238; 3,5-Difluoroaniline.
DR   DrugBank; DB01957; 3-Chlorophenol.
DR   DrugBank; DB01986; 3-Fluoro-2-Methyl-Aniline.
DR   DrugBank; DB03669; 4-Fluorophenethyl Alcohol.
DR   DrugBank; DB03660; 4-Iodo-L-phenylalanine.
DR   DrugBank; DB01932; 5-Methylpyrrole.
DR   DrugBank; DB04179; Benzofuran.
DR   DrugBank; DB00536; Guanidine.
DR   DrugBank; DB02210; Hexane-1,6-Diol.
DR   DrugBank; DB04532; Indole.
DR   DrugBank; DB03345; Mercaptoethanol.
DR   DrugBank; DB02870; N-Allylaniline.
DR   DrugBank; DB08456; S-[(1-Hydroxy-2,2,5,5-tetramethyl-4-phenyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate.
DR   DrugBank; DB00373; Timolol.
DR   DrugCentral; P00720; -.
DR   CAZy; GH24; Glycoside Hydrolase Family 24.
DR   GeneID; 1258585; -.
DR   KEGG; vg:1258585; -.
DR   BRENDA; 3.2.1.17; 732.
DR   EvolutionaryTrace; P00720; -.
DR   Proteomes; UP000009087; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003796; F:lysozyme activity; IDA:UniProtKB.
DR   GO; GO:0016998; P:cell wall macromolecule catabolic process; IEA:InterPro.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0009253; P:peptidoglycan catabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0044659; P:viral release from host cell by cytolysis; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.530.40; -; 1.
DR   HAMAP; MF_04110; ENDOLYSIN_T4; 1.
DR   InterPro; IPR034690; Endolysin_T4_type.
DR   InterPro; IPR002196; Glyco_hydro_24.
DR   InterPro; IPR023346; Lysozyme-like_dom_sf.
DR   InterPro; IPR023347; Lysozyme_dom_sf.
DR   InterPro; IPR001165; T4-type_lysozyme.
DR   Pfam; PF00959; Phage_lysozyme; 1.
DR   PRINTS; PR00684; T4LYSOZYME.
DR   SUPFAM; SSF53955; SSF53955; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Antimicrobial; Bacteriolytic enzyme; Cytolysis;
KW   Direct protein sequencing; Glycosidase; Host cell lysis by virus;
KW   Host cytoplasm; Hydrolase; Reference proteome;
KW   Viral release from host cell.
FT   CHAIN           1..164
FT                   /note="Endolysin"
FT                   /id="PRO_0000218107"
FT   ACT_SITE        11
FT                   /note="Proton donor/acceptor"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_04110,
FT                   ECO:0000269|PubMed:3382407, ECO:0000269|PubMed:7831309,
FT                   ECO:0000269|PubMed:8266098"
FT   ACT_SITE        20
FT                   /note="Proton donor/acceptor"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_04110,
FT                   ECO:0000269|PubMed:1892846, ECO:0000269|PubMed:3382407,
FT                   ECO:0000269|PubMed:7831309, ECO:0000269|PubMed:8266098"
FT   BINDING         32
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000269|PubMed:8266098"
FT   BINDING         104
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000269|PubMed:8266098"
FT   BINDING         117
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000303|PubMed:7831309"
FT   BINDING         132
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000303|PubMed:7831309"
FT   MUTAGEN         11
FT                   /note="E->A,F,H,M,N: Complete loss of enzymatic activity."
FT                   /evidence="ECO:0000269|PubMed:7831309"
FT   MUTAGEN         11
FT                   /note="E->N: Loss of 84% of enzymatic activity."
FT                   /evidence="ECO:0000269|PubMed:3382407"
FT   MUTAGEN         11
FT                   /note="E->Q: Complete loss of activity."
FT                   /evidence="ECO:0000269|PubMed:3382407"
FT   MUTAGEN         20
FT                   /note="D->A,N,S,T: Complete loss of enzymatic activity."
FT                   /evidence="ECO:0000269|PubMed:7831309"
FT   MUTAGEN         20
FT                   /note="D->C: Nearly no effet on specific enzymatic
FT                   activity."
FT                   /evidence="ECO:0000269|PubMed:1892846"
FT   MUTAGEN         20
FT                   /note="D->E,Q: Loss of 99% of enzymatic activity."
FT                   /evidence="ECO:0000269|PubMed:3382407"
FT   MUTAGEN         26
FT                   /note="T->E: Complete loss of activity at neutral pH;
FT                   covalently bound substrate."
FT                   /evidence="ECO:0000269|PubMed:8266098"
FT   MUTAGEN         26
FT                   /note="T->H: Facilitates transglycosylation more
FT                   effectively than hydrolysis; covalently bound substrate."
FT                   /evidence="ECO:0000269|PubMed:28707339"
FT   MUTAGEN         30
FT                   /note="G->A: Almost complete loss of enzymatic activity."
FT                   /evidence="ECO:0000269|PubMed:7831309"
FT   MUTAGEN         30
FT                   /note="G->F: Almost complete loss of enzymatic activity.
FT                   The enzyme is destabilized by 1.5 kcal/mol."
FT                   /evidence="ECO:0000269|PubMed:7831309"
FT   MUTAGEN         117
FT                   /note="S->F: 10-fold decrease in enzymatic activity."
FT                   /evidence="ECO:0000269|PubMed:7831309"
FT   MUTAGEN         117
FT                   /note="S->I: 500-fold decrease in enzymatic activity."
FT                   /evidence="ECO:0000269|PubMed:7831309"
FT   MUTAGEN         117
FT                   /note="S->V: 50-fold decrease in enzymatic activity."
FT                   /evidence="ECO:0000269|PubMed:7831309"
FT   MUTAGEN         132
FT                   /note="N->I: 5-fold decrease in enzymatic activity."
FT                   /evidence="ECO:0000269|PubMed:7831309"
FT   MUTAGEN         132
FT                   /note="N->M,F: 2-fold decrease in enzymatic activity."
FT                   /evidence="ECO:0000269|PubMed:7831309"
FT   CONFLICT        12
FT                   /note="R -> G (in Ref. 1; AA sequence)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        137
FT                   /note="I -> R (in Ref. 1; AA sequence)"
FT                   /evidence="ECO:0000305"
FT   HELIX           3..11
FT                   /evidence="ECO:0007829|PDB:5JDT"
FT   STRAND          14..19
FT                   /evidence="ECO:0007829|PDB:5JDT"
FT   STRAND          21..23
FT                   /evidence="ECO:0007829|PDB:5V88"
FT   STRAND          25..28
FT                   /evidence="ECO:0007829|PDB:5JDT"
FT   STRAND          31..37
FT                   /evidence="ECO:0007829|PDB:7LOE"
FT   HELIX           39..50
FT                   /evidence="ECO:0007829|PDB:5JDT"
FT   STRAND          55..57
FT                   /evidence="ECO:0007829|PDB:3HH3"
FT   HELIX           62..64
FT                   /evidence="ECO:0007829|PDB:2O7A"
FT   STRAND          65..67
FT                   /evidence="ECO:0007829|PDB:6D26"
FT   HELIX           68..79
FT                   /evidence="ECO:0007829|PDB:2O7A"
FT   TURN            82..84
FT                   /evidence="ECO:0007829|PDB:2O7A"
FT   HELIX           85..90
FT                   /evidence="ECO:0007829|PDB:2O7A"
FT   HELIX           93..106
FT                   /evidence="ECO:0007829|PDB:2O7A"
FT   HELIX           108..112
FT                   /evidence="ECO:0007829|PDB:2O7A"
FT   HELIX           115..122
FT                   /evidence="ECO:0007829|PDB:2O7A"
FT   TURN            123..125
FT                   /evidence="ECO:0007829|PDB:209L"
FT   HELIX           126..133
FT                   /evidence="ECO:0007829|PDB:2O7A"
FT   STRAND          134..136
FT                   /evidence="ECO:0007829|PDB:6MXT"
FT   HELIX           137..141
FT                   /evidence="ECO:0007829|PDB:2O7A"
FT   HELIX           143..155
FT                   /evidence="ECO:0007829|PDB:2O7A"
FT   STRAND          156..158
FT                   /evidence="ECO:0007829|PDB:7LOE"
FT   TURN            159..161
FT                   /evidence="ECO:0007829|PDB:2O7A"
FT   HELIX           162..164
FT                   /evidence="ECO:0007829|PDB:4ARJ"
SQ   SEQUENCE   164 AA;  18692 MW;  02D568CC8FC81CF1 CRC64;
     MNIFEMLRID ERLRLKIYKD TEGYYTIGIG HLLTKSPSLN AAKSELDKAI GRNCNGVITK
     DEAEKLFNQD VDAAVRGILR NAKLKPVYDS LDAVRRCALI NMVFQMGETG VAGFTNSLRM
     LQQKRWDEAA VNLAKSIWYN QTPNRAKRVI TTFRTGTWDA YKNL
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024