AGL1_ARATH
ID AGL1_ARATH Reviewed; 248 AA.
AC P29381;
DT 01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-1992, sequence version 1.
DT 25-MAY-2022, entry version 161.
DE RecName: Full=Agamous-like MADS-box protein AGL1;
DE AltName: Full=Protein SHATTERPROOF 1;
GN Name=AGL1; Synonyms=SHP1; OrderedLocusNames=At3g58780; ORFNames=T20N10_130;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=1672119; DOI=10.1101/gad.5.3.484;
RA Ma H., Yanofsky M.F., Meyerowitz E.M.;
RT "AGL1-AGL6, an Arabidopsis gene family with similarity to floral homeotic
RT and transcription factor genes.";
RL Genes Dev. 5:484-495(1991).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP INTERACTION WITH AGL15 AND AGL16.
RX PubMed=15805477; DOI=10.1105/tpc.105.031831;
RA de Folter S., Immink R.G.H., Kieffer M., Parenicova L., Henz S.R.,
RA Weigel D., Busscher M., Kooiker M., Colombo L., Kater M.M., Davies B.,
RA Angenent G.C.;
RT "Comprehensive interaction map of the Arabidopsis MADS Box transcription
RT factors.";
RL Plant Cell 17:1424-1433(2005).
RN [6]
RP FUNCTION.
RX PubMed=27776173; DOI=10.1371/journal.pone.0165075;
RA Ehlers K., Bhide A.S., Tekleyohans D.G., Wittkop B., Snowdon R.J.,
RA Becker A.;
RT "The MADS box genes ABS, SHP1, and SHP2 are essential for the coordination
RT of cell divisions in ovule and seed coat development and for endosperm
RT formation in Arabidopsis thaliana.";
RL PLoS ONE 11:E0165075-E0165075(2016).
CC -!- FUNCTION: Probable transcription factor. Interacts genetically with
CC TT16/AGL32 in a partially antagonistic manner during flower
CC development. Is essential for the coordination of cell divisions in
CC ovule, seed coat development and endosperm formation (PubMed:27776173).
CC {ECO:0000269|PubMed:27776173}.
CC -!- SUBUNIT: Interacts with AGL15 and AGL16. {ECO:0000269|PubMed:15805477}.
CC -!- INTERACTION:
CC P29381; Q9SZJ6: AGL21; NbExp=4; IntAct=EBI-592304, EBI-621986;
CC P29381; O22456: SEP3; NbExp=5; IntAct=EBI-592304, EBI-592020;
CC -!- SUBCELLULAR LOCATION: Nucleus.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=P29381-1; Sequence=Displayed;
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DR EMBL; M55550; AAA32730.1; -; mRNA.
DR EMBL; AL353032; CAB88295.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE79829.1; -; Genomic_DNA.
DR EMBL; AY086196; AAM64275.1; -; mRNA.
DR PIR; A39534; A39534.
DR RefSeq; NP_191437.1; NM_115740.3. [P29381-1]
DR AlphaFoldDB; P29381; -.
DR SMR; P29381; -.
DR BioGRID; 10362; 24.
DR IntAct; P29381; 17.
DR STRING; 3702.AT3G58780.3; -.
DR PRIDE; P29381; -.
DR EnsemblPlants; AT3G58780.1; AT3G58780.1; AT3G58780. [P29381-1]
DR GeneID; 825047; -.
DR Gramene; AT3G58780.1; AT3G58780.1; AT3G58780. [P29381-1]
DR KEGG; ath:AT3G58780; -.
DR Araport; AT3G58780; -.
DR eggNOG; KOG0014; Eukaryota.
DR HOGENOM; CLU_053053_0_0_1; -.
DR InParanoid; P29381; -.
DR PhylomeDB; P29381; -.
DR PRO; PR:P29381; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; P29381; baseline and differential.
DR Genevisible; P29381; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:InterPro.
DR GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00265; MADS_MEF2_like; 1.
DR Gene3D; 3.40.1810.10; -; 1.
DR InterPro; IPR033896; MADS_MEF2-like.
DR InterPro; IPR002487; TF_Kbox.
DR InterPro; IPR002100; TF_MADSbox.
DR InterPro; IPR036879; TF_MADSbox_sf.
DR Pfam; PF01486; K-box; 1.
DR Pfam; PF00319; SRF-TF; 1.
DR PRINTS; PR00404; MADSDOMAIN.
DR SMART; SM00432; MADS; 1.
DR SUPFAM; SSF55455; SSF55455; 1.
DR PROSITE; PS51297; K_BOX; 1.
DR PROSITE; PS00350; MADS_BOX_1; 1.
DR PROSITE; PS50066; MADS_BOX_2; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Developmental protein; DNA-binding; Flowering;
KW Growth regulation; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..248
FT /note="Agamous-like MADS-box protein AGL1"
FT /id="PRO_0000199457"
FT DOMAIN 18..72
FT /note="MADS-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00251"
FT DOMAIN 102..192
FT /note="K-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00629"
SQ SEQUENCE 248 AA; 28336 MW; D377C47F231F2099 CRC64;
MEEGGSSHDA ESSKKLGRGK IEIKRIENTT NRQVTFCKRR NGLLKKAYEL SVLCDAEVAL
VIFSTRGRLY EYANNSVRGT IERYKKACSD AVNPPSVTEA NTQYYQQEAS KLRRQIRDIQ
NSNRHIVGES LGSLNFKELK NLEGRLEKGI SRVRSKKNEL LVAEIEYMQK REMELQHNNM
YLRAKIAEGA RLNPDQQESS VIQGTTVYES GVSSHDQSQH YNRNYIPVNL LEPNQQFSGQ
DQPPLQLV
