AGL23_ARATH
ID AGL23_ARATH Reviewed; 226 AA.
AC O80807;
DT 14-OCT-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 150.
DE RecName: Full=Agamous-like MADS-box protein AGL23 {ECO:0000305};
GN Name=AGL23 {ECO:0000303|PubMed:12837945};
GN OrderedLocusNames=At1g65360 {ECO:0000312|Araport:AT1G65360};
GN ORFNames=T8F5.14 {ECO:0000312|EMBL:AAC27145.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12837945; DOI=10.1105/tpc.011544;
RA Parenicova L., de Folter S., Kieffer M., Horner D.S., Favalli C.,
RA Busscher J., Cook H.E., Ingram R.M., Kater M.M., Davies B., Angenent G.C.,
RA Colombo L.;
RT "Molecular and phylogenetic analyses of the complete MADS-box transcription
RT factor family in Arabidopsis: new openings to the MADS world.";
RL Plant Cell 15:1538-1551(2003).
RN [5]
RP FUNCTION, DEVELOPMENTAL STAGE, AND DISRUPTION PHENOTYPE.
RX PubMed=18346189; DOI=10.1111/j.1365-313x.2008.03485.x;
RA Colombo M., Masiero S., Vanzulli S., Lardelli P., Kater M.M., Colombo L.;
RT "AGL23, a type I MADS-box gene that controls female gametophyte and embryo
RT development in Arabidopsis.";
RL Plant J. 54:1037-1048(2008).
RN [6]
RP DEVELOPMENTAL STAGE.
RX PubMed=20631316; DOI=10.1104/pp.110.160770;
RA Bemer M., Heijmans K., Airoldi C., Davies B., Angenent G.C.;
RT "An atlas of type I MADS box gene expression during female gametophyte and
RT seed development in Arabidopsis.";
RL Plant Physiol. 154:287-300(2010).
CC -!- FUNCTION: Probable transcription factor that controls female
CC gametophyte (megagametogenesis) development and chloroplast biogenesis
CC during embryo development. {ECO:0000269|PubMed:18346189}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00251}.
CC -!- DEVELOPMENTAL STAGE: During embryo development, expressed in the
CC functional megaspore until maturity of the embryo sac. After
CC fertilization, expressed in the embryo and endosperm until the early
CC torpedo stage. Not expressed in mature embryo.
CC {ECO:0000269|PubMed:18346189}.
CC -!- DISRUPTION PHENOTYPE: Embryonic lethality when homozygous.
CC {ECO:0000269|PubMed:18346189}.
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DR EMBL; AC004512; AAC27145.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE34365.1; -; Genomic_DNA.
DR EMBL; AY141230; AAN52794.1; -; mRNA.
DR PIR; T02359; T02359.
DR RefSeq; NP_176715.1; NM_105210.2.
DR AlphaFoldDB; O80807; -.
DR SMR; O80807; -.
DR IntAct; O80807; 12.
DR STRING; 3702.AT1G65360.1; -.
DR PaxDb; O80807; -.
DR PRIDE; O80807; -.
DR EnsemblPlants; AT1G65360.1; AT1G65360.1; AT1G65360.
DR GeneID; 842846; -.
DR Gramene; AT1G65360.1; AT1G65360.1; AT1G65360.
DR KEGG; ath:AT1G65360; -.
DR Araport; AT1G65360; -.
DR TAIR; locus:2206320; AT1G65360.
DR eggNOG; KOG0014; Eukaryota.
DR HOGENOM; CLU_053053_5_3_1; -.
DR InParanoid; O80807; -.
DR OMA; CDAKIAM; -.
DR OrthoDB; 1516449at2759; -.
DR PhylomeDB; O80807; -.
DR PRO; PR:O80807; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; O80807; baseline and differential.
DR Genevisible; O80807; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0009658; P:chloroplast organization; IMP:TAIR.
DR GO; GO:0009553; P:embryo sac development; IMP:TAIR.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 3.40.1810.10; -; 1.
DR InterPro; IPR002100; TF_MADSbox.
DR InterPro; IPR036879; TF_MADSbox_sf.
DR Pfam; PF00319; SRF-TF; 1.
DR PRINTS; PR00404; MADSDOMAIN.
DR SMART; SM00432; MADS; 1.
DR SUPFAM; SSF55455; SSF55455; 1.
DR PROSITE; PS50066; MADS_BOX_2; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..226
FT /note="Agamous-like MADS-box protein AGL23"
FT /id="PRO_0000433963"
FT DOMAIN 6..66
FT /note="MADS-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00251"
FT REGION 108..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 95..132
FT /evidence="ECO:0000255"
SQ SEQUENCE 226 AA; 25337 MW; 6F6833ED4E5E864E CRC64;
MVKKTLGRRK VEIVKMTKES NLQVTFSKRK AGLFKKASEF CTLCDAKIAM IVFSPAGKVF
SFGHPNVDVL LDHFRGCVVG HNNTNLDESY TKLHVQMLNK SYTEVKAEVE KEQKNKQSRA
QNERENENAE EWWSKSPLEL NLSQSTCMIR VLKDLKKIVD EKAIQLIHQT NPNFYVGSSS
NAAAPATVSG GNISTNQGFF DQNGMTTNPT QTLLFGFDIM NRTPGV
