AGL28_ARATH
ID AGL28_ARATH Reviewed; 247 AA.
AC Q9LMM8; A0ME51; O23700;
DT 14-OCT-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 151.
DE RecName: Full=Agamous-like MADS-box protein AGL28 {ECO:0000305};
GN Name=AGL28 {ECO:0000303|PubMed:12837945};
GN OrderedLocusNames=At1g01530 {ECO:0000312|Araport:AT1G01530};
GN ORFNames=F22L4.7 {ECO:0000312|EMBL:AAF81311.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia; TISSUE=Flower;
RX PubMed=12837945; DOI=10.1105/tpc.011544;
RA Parenicova L., de Folter S., Kieffer M., Horner D.S., Favalli C.,
RA Busscher J., Cook H.E., Ingram R.M., Kater M.M., Davies B., Angenent G.C.,
RA Colombo L.;
RT "Molecular and phylogenetic analyses of the complete MADS-box transcription
RT factor family in Arabidopsis: new openings to the MADS world.";
RL Plant Cell 15:1538-1551(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9666060; DOI=10.1016/s0378-1119(98)00286-8;
RA Terryn N., Gielen J., De Keyser A., Van Den Daele H., Ardiles W., Neyt P.,
RA De Clercq R., Coppieters J., Dehais P., Villarroel R., Rouze P.,
RA van Montagu M.;
RT "Sequence analysis of a 40-kb Arabidopsis thaliana genomic region located
RT at the top of chromosome 1.";
RL Gene 215:11-17(1998).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Fujita M., Mizukado S., Seki M., Shinozaki K., Mitsuda N., Takiguchi Y.,
RA Takagi M.;
RT "ORF cloning and analysis of Arabidopsis transcription factor genes.";
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP FUNCTION, TISSUE SPECIFICITY, AND DISRUPTION PHENOTYPE.
RX PubMed=16899218; DOI=10.1016/j.bbrc.2006.07.121;
RA Yoo S.K., Lee J.S., Ahn J.H.;
RT "Overexpression of AGAMOUS-LIKE 28 (AGL28) promotes flowering by
RT upregulating expression of floral promoters within the autonomous
RT pathway.";
RL Biochem. Biophys. Res. Commun. 348:929-936(2006).
RN [8]
RP DEVELOPMENTAL STAGE.
RX PubMed=20631316; DOI=10.1104/pp.110.160770;
RA Bemer M., Heijmans K., Airoldi C., Davies B., Angenent G.C.;
RT "An atlas of type I MADS box gene expression during female gametophyte and
RT seed development in Arabidopsis.";
RL Plant Physiol. 154:287-300(2010).
CC -!- FUNCTION: Probable transcription factor that may function as a floral
CC promoter operating upstream of known floral activators in the
CC autonomous pathway. {ECO:0000269|PubMed:16899218}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00251}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, leaves and shoot apices.
CC {ECO:0000269|PubMed:16899218}.
CC -!- DEVELOPMENTAL STAGE: Expressed in the embryo at the globular stage and
CC in endosperm nuclei and chalazal endosperm of developing seeds.
CC {ECO:0000269|PubMed:16899218}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC conditions. {ECO:0000269|PubMed:16899218}.
CC -!- MISCELLANEOUS: Plants over-expressing AGL28 show an early flowering
CC phenotype. {ECO:0000269|PubMed:16899218}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABK28380.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
CC Sequence=CAA73304.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AY141231; AAN52795.1; -; mRNA.
DR EMBL; Y12776; CAA73304.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC061957; AAF81311.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE27300.1; -; Genomic_DNA.
DR EMBL; DQ446218; ABE65591.1; -; mRNA.
DR EMBL; DQ652819; ABK28380.1; ALT_SEQ; mRNA.
DR EMBL; AB493420; BAH30258.1; -; mRNA.
DR PIR; H86145; H86145.
DR RefSeq; NP_171660.1; NM_100035.3.
DR AlphaFoldDB; Q9LMM8; -.
DR SMR; Q9LMM8; -.
DR IntAct; Q9LMM8; 4.
DR STRING; 3702.AT1G01530.1; -.
DR PaxDb; Q9LMM8; -.
DR PRIDE; Q9LMM8; -.
DR EnsemblPlants; AT1G01530.1; AT1G01530.1; AT1G01530.
DR GeneID; 837142; -.
DR Gramene; AT1G01530.1; AT1G01530.1; AT1G01530.
DR KEGG; ath:AT1G01530; -.
DR Araport; AT1G01530; -.
DR TAIR; locus:2025386; AT1G01530.
DR eggNOG; KOG0014; Eukaryota.
DR HOGENOM; CLU_053053_5_3_1; -.
DR InParanoid; Q9LMM8; -.
DR OMA; NVMNRTP; -.
DR OrthoDB; 1516449at2759; -.
DR PhylomeDB; Q9LMM8; -.
DR PRO; PR:Q9LMM8; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9LMM8; baseline and differential.
DR Genevisible; Q9LMM8; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0009911; P:positive regulation of flower development; IMP:UniProtKB.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00265; MADS_MEF2_like; 1.
DR Gene3D; 3.40.1810.10; -; 1.
DR InterPro; IPR033896; MADS_MEF2-like.
DR InterPro; IPR002100; TF_MADSbox.
DR InterPro; IPR036879; TF_MADSbox_sf.
DR Pfam; PF00319; SRF-TF; 1.
DR PRINTS; PR00404; MADSDOMAIN.
DR SMART; SM00432; MADS; 1.
DR SUPFAM; SSF55455; SSF55455; 1.
DR PROSITE; PS50066; MADS_BOX_2; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..247
FT /note="Agamous-like MADS-box protein AGL28"
FT /id="PRO_0000433964"
FT DOMAIN 6..66
FT /note="MADS-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00251"
FT COILED 91..168
FT /evidence="ECO:0000255"
SQ SEQUENCE 247 AA; 28030 MW; 13B58391A7FD3631 CRC64;
MARKNLGRRK IELVKMTNES NLQVTFSKRR SGLFKKGSEL CTLCDAEIAI IVFSPSGKAY
SFGHPNVNKL LDHSLGRVIR HNNTNFAESR TKLRIQMLNE SLTEVMAEKE KEQETKQSIV
QNERENKDAE KWWRNSPTEL NLAQSTSMKC DLEALKKEVD EKVAQLHHRN LNFYVGSSSN
VAAPAAVSGG NISTNHGFFD QNGNSTSAPT LPFGFNVMNR TPAGYNSYQL QNQEVKQVHP
QYWARYY
