AGL72_ARATH
ID AGL72_ARATH Reviewed; 211 AA.
AC Q9FLH5; A0MFN4; Q1PDK7;
DT 13-APR-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 153.
DE RecName: Full=MADS-box protein AGL72;
DE AltName: Full=Protein AGAMOUS-LIKE 72;
GN Name=AGL72; OrderedLocusNames=At5g51860 {ECO:0000312|Araport:AT5G51860};
GN ORFNames=MJM18.1 {ECO:0000312|EMBL:BAB11255.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia; TISSUE=Flower;
RX PubMed=12837945; DOI=10.1105/tpc.011544;
RA Parenicova L., de Folter S., Kieffer M., Horner D.S., Favalli C.,
RA Busscher J., Cook H.E., Ingram R.M., Kater M.M., Davies B., Angenent G.C.,
RA Colombo L.;
RT "Molecular and phylogenetic analyses of the complete MADS-box transcription
RT factor family in Arabidopsis: new openings to the MADS world.";
RL Plant Cell 15:1538-1551(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9628582; DOI=10.1093/dnares/5.1.41;
RA Sato S., Kaneko T., Kotani H., Nakamura Y., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. IV. Sequence
RT features of the regions of 1,456,315 bp covered by nineteen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:41-54(1998).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [6]
RP FUNCTION, DEVELOPMENTAL STAGE, AND DISRUPTION PHENOTYPE.
RX PubMed=21609362; DOI=10.1111/j.1365-313x.2011.04653.x;
RA Dorca-Fornell C., Gregis V., Grandi V., Coupland G., Colombo L.,
RA Kater M.M.;
RT "The Arabidopsis SOC1-like genes AGL42, AGL71 and AGL72 promote flowering
RT in the shoot apical and axillary meristems.";
RL Plant J. 67:1006-1017(2011).
CC -!- FUNCTION: MADS-box transcription factor that acts with AGL42 and AGL71
CC in the control of flowering time. Promotes flowering at the shoot
CC apical and axillary meristems. Seems to act through a gibberellin-
CC dependent pathway. Interacts genetically with SOC1 and its expression
CC is directly regulated by SOC1. {ECO:0000269|PubMed:21609362}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00251}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9FLH5-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9FLH5-2; Sequence=VSP_058214;
CC -!- DEVELOPMENTAL STAGE: Expressed in the shoot apical meristem (SAM)
CC during the vegetative phase and the floral transition. After floral
CC transition, expressed in apical meristem (AM), inflorescence meristem
CC (IM) and floral primordia. {ECO:0000269|PubMed:21609362}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC conditions. {ECO:0000269|PubMed:21609362}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABK28751.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR EMBL; AY141221; AAN52785.1; -; mRNA.
DR EMBL; AB010074; BAB11255.1; -; Genomic_DNA.
DR EMBL; AB025623; BAB11255.1; JOINED; Genomic_DNA.
DR EMBL; CP002688; AED96136.1; -; Genomic_DNA.
DR EMBL; CP002688; AED96137.1; -; Genomic_DNA.
DR EMBL; DQ447061; ABE66238.1; -; mRNA.
DR EMBL; DQ653360; ABK28751.1; ALT_SEQ; mRNA.
DR RefSeq; NP_001078745.1; NM_001085276.1. [Q9FLH5-2]
DR RefSeq; NP_199999.1; NM_124565.2. [Q9FLH5-1]
DR AlphaFoldDB; Q9FLH5; -.
DR SMR; Q9FLH5; -.
DR IntAct; Q9FLH5; 1.
DR STRING; 3702.AT5G51860.1; -.
DR PaxDb; Q9FLH5; -.
DR PRIDE; Q9FLH5; -.
DR EnsemblPlants; AT5G51860.1; AT5G51860.1; AT5G51860. [Q9FLH5-1]
DR EnsemblPlants; AT5G51860.2; AT5G51860.2; AT5G51860. [Q9FLH5-2]
DR GeneID; 835261; -.
DR Gramene; AT5G51860.1; AT5G51860.1; AT5G51860. [Q9FLH5-1]
DR Gramene; AT5G51860.2; AT5G51860.2; AT5G51860. [Q9FLH5-2]
DR KEGG; ath:AT5G51860; -.
DR Araport; AT5G51860; -.
DR TAIR; locus:2165386; AT5G51860.
DR eggNOG; KOG0014; Eukaryota.
DR InParanoid; Q9FLH5; -.
DR OMA; LEKDHWG; -.
DR OrthoDB; 1235442at2759; -.
DR PhylomeDB; Q9FLH5; -.
DR PRO; PR:Q9FLH5; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FLH5; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:InterPro.
DR GO; GO:0009909; P:regulation of flower development; IMP:TAIR.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00265; MADS_MEF2_like; 1.
DR Gene3D; 3.40.1810.10; -; 1.
DR InterPro; IPR033896; MADS_MEF2-like.
DR InterPro; IPR002487; TF_Kbox.
DR InterPro; IPR002100; TF_MADSbox.
DR InterPro; IPR036879; TF_MADSbox_sf.
DR Pfam; PF01486; K-box; 1.
DR Pfam; PF00319; SRF-TF; 1.
DR PRINTS; PR00404; MADSDOMAIN.
DR SMART; SM00432; MADS; 1.
DR SUPFAM; SSF55455; SSF55455; 1.
DR PROSITE; PS51297; K_BOX; 1.
DR PROSITE; PS50066; MADS_BOX_2; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Developmental protein; Differentiation; DNA-binding;
KW Flowering; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..211
FT /note="MADS-box protein AGL72"
FT /id="PRO_0000436029"
FT DOMAIN 1..61
FT /note="MADS-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00251"
FT DOMAIN 88..187
FT /note="K-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00629"
FT VAR_SEQ 172..180
FT /note="Missing (in isoform 2)"
FT /id="VSP_058214"
SQ SEQUENCE 211 AA; 24634 MW; 1926F4E45B9B0B95 CRC64;
MVRGKIEIKK IENVTSRQVT FSKRRSGLFK KAHELSVLCD AQVAAMIFSQ KGRLYEFASS
DIRNTIKRYA EYKREYFVAE THPIEQYVQG LKKEMVTMVK KIEVLEVHNR KMMGQSLDSC
SVKELSEIAT QIEKSLHMVR LRKAKLYEDE LQKLKAKERE LKDERVRLSL KKTIYTHLCQ
VGERPMGMPS GSKEKEDVET DLFIGFLKNR P
