AGLF_RHIME
ID AGLF_RHIME Reviewed; 336 AA.
AC Q9Z3R6;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 02-NOV-2001, sequence version 2.
DT 25-MAY-2022, entry version 112.
DE RecName: Full=Alpha-glucoside transport system permease protein AglF;
GN Name=aglF; OrderedLocusNames=R00696; ORFNames=SMc03062;
OS Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS meliloti).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=266834;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=10400573; DOI=10.1128/jb.181.14.4176-4184.1999;
RA Willis L.B., Walker G.C.;
RT "A novel Sinorhizobium meliloti operon encodes an alpha-glucosidase and a
RT periplasmic-binding-protein-dependent transport system for alpha-
RT glucosides.";
RL J. Bacteriol. 181:4176-4184(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11481430; DOI=10.1073/pnas.161294398;
RA Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT meliloti strain 1021.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11474104; DOI=10.1126/science.1060966;
RA Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA Wong K., Yeh K.-C., Batut J.;
RT "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL Science 293:668-672(2001).
CC -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC alpha-glucosides such as sucrose, maltose and trehalose. Probably
CC responsible for the translocation of the substrate across the membrane.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. MalFG subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD12049.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AF045609; AAD12049.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL591688; CAC45268.1; -; Genomic_DNA.
DR RefSeq; NP_384802.1; NC_003047.1.
DR RefSeq; WP_003529835.1; NC_003047.1.
DR AlphaFoldDB; Q9Z3R6; -.
DR SMR; Q9Z3R6; -.
DR STRING; 266834.SMc03062; -.
DR TCDB; 3.A.1.1.8; the atp-binding cassette (abc) superfamily.
DR EnsemblBacteria; CAC45268; CAC45268; SMc03062.
DR GeneID; 61602163; -.
DR KEGG; sme:SMc03062; -.
DR PATRIC; fig|266834.11.peg.2071; -.
DR eggNOG; COG1175; Bacteria.
DR HOGENOM; CLU_016047_0_0_5; -.
DR OMA; LTMTNGQ; -.
DR BRENDA; 7.5.2.B9; 5347.
DR Proteomes; UP000001976; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; -; 1.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR Pfam; PF00528; BPD_transp_1; 1.
DR SUPFAM; SSF161098; SSF161098; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Sugar transport; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..336
FT /note="Alpha-glucoside transport system permease protein
FT AglF"
FT /id="PRO_0000059940"
FT TRANSMEM 4..24
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 55..75
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 146..166
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 176..196
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 202..222
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 258..278
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 304..324
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 109..325
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT CONFLICT 316..317
FT /note="IL -> NP (in Ref. 1; AAD12049)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 336 AA; 37399 MW; 0E75C0FEEA810F73 CRC64;
MEQLIAAILT MVAGVLVCAA YFWSTNLVLD WIFPSKGKFG AVASRNLRIA NSIRPWLFLA
PALLALTLYL VYPVVQSVWL SLHGRGGQNF VGLSNYSWMI NDGEFRQSIF NNFLWLLVVP
ALSTFFGLII AALTDRIWWG NIAKTLIFMP MAISFVGAAV IWKFIYDYRA AGSEQIGLLN
AIVVALGGEP QAWITLPFWN NFFLMVILIW IQTGFAMVIL SAALRGIPEE TIEAAVIDGA
NGWQIFFKIM VPQIWGTIAV VWTTITILVL KVFDIVLAMT NGQWQSQVLA NLMFDWMFRG
GGDFGRGAAI AVVIMILVVP IMIWNIRNAT RESGGH
