AGLK_RHIME
ID AGLK_RHIME Reviewed; 362 AA.
AC Q9Z3R9;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 24-OCT-2001, sequence version 2.
DT 03-AUG-2022, entry version 138.
DE RecName: Full=Alpha-glucoside transport ATP-binding protein AglK;
GN Name=aglK; OrderedLocusNames=R00699; ORFNames=SMc03065;
OS Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS meliloti).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=266834;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=10400573; DOI=10.1128/jb.181.14.4176-4184.1999;
RA Willis L.B., Walker G.C.;
RT "A novel Sinorhizobium meliloti operon encodes an alpha-glucosidase and a
RT periplasmic-binding-protein-dependent transport system for alpha-
RT glucosides.";
RL J. Bacteriol. 181:4176-4184(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11481430; DOI=10.1073/pnas.161294398;
RA Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT meliloti strain 1021.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11474104; DOI=10.1126/science.1060966;
RA Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA Wong K., Yeh K.-C., Batut J.;
RT "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL Science 293:668-672(2001).
CC -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC alpha-glucosides such as sucrose, maltose and trehalose. Probably
CC responsible for energy coupling to the transport system.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Peripheral
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR EMBL; AF045609; AAD12046.1; -; Genomic_DNA.
DR EMBL; AL591688; CAC45271.1; -; Genomic_DNA.
DR RefSeq; NP_384805.1; NC_003047.1.
DR RefSeq; WP_003529832.1; NC_003047.1.
DR AlphaFoldDB; Q9Z3R9; -.
DR SMR; Q9Z3R9; -.
DR STRING; 266834.SMc03065; -.
DR TCDB; 3.A.1.1.8; the atp-binding cassette (abc) superfamily.
DR PRIDE; Q9Z3R9; -.
DR EnsemblBacteria; CAC45271; CAC45271; SMc03065.
DR GeneID; 61602166; -.
DR KEGG; sme:SMc03065; -.
DR PATRIC; fig|266834.11.peg.2074; -.
DR eggNOG; COG3842; Bacteria.
DR HOGENOM; CLU_000604_1_1_5; -.
DR OMA; HVENMGA; -.
DR BRENDA; 7.5.2.B9; 5347.
DR Proteomes; UP000001976; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR CDD; cd03301; ABC_MalK_N; 1.
DR Gene3D; 2.40.50.140; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR015855; ABC_transpr_MalK-like.
DR InterPro; IPR008995; Mo/tungstate-bd_C_term_dom.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR040582; OB_MalK.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005116; Transp-assoc_OB_typ1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF17912; OB_MalK; 1.
DR Pfam; PF03459; TOBE; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF50331; SSF50331; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW Nucleotide-binding; Reference proteome; Sugar transport; Transport.
FT CHAIN 1..362
FT /note="Alpha-glucoside transport ATP-binding protein AglK"
FT /id="PRO_0000091924"
FT DOMAIN 4..235
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 36..43
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT CONFLICT 173..185
FT /note="RIEIAKLSERMSD -> AIENRQAQRAMSN (in Ref. 1)"
FT /evidence="ECO:0000305"
FT CONFLICT 208..216
FT /note="LSAGHIEQV -> FSRRSTFEQF (in Ref. 1; AAD12046)"
FT /evidence="ECO:0000305"
FT CONFLICT 220
FT /note="L -> F (in Ref. 1; AAD12046)"
FT /evidence="ECO:0000305"
FT CONFLICT 229
FT /note="L -> F (in Ref. 1; AAD12046)"
FT /evidence="ECO:0000305"
FT CONFLICT 239
FT /note="A -> P (in Ref. 1; AAD12046)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 362 AA; 39463 MW; 66B76CF47FE95A39 CRC64;
MTGLLLKDIR KSYGAVDVIH GIDLDIKEGE FVVFVGPSGC GKSTLLRMIA GLEEITGGDM
FIDGERVNDV PPSKRGIAMV FQSYALYPHM TVYDNMAFGM RIARESKEEI DRRVRGAADM
LQLTPYLDRL PKALSGGQRQ RVAIGRAICR NPKVFLFDEP LSNLDAALRV ATRIEIAKLS
ERMSDTTMIY VTHDQVEAMT LADRIVVLSA GHIEQVGAPL ELYERPANLF VARFIGSPAM
NVIPATITAT GQQTAVSLAG GKSVTLDVPT NASENGKTAS FGVRPEDLRV TEADDFLFEG
TVSIVEALGE VTLLYIEGLV ENEPIIAKMP GIARVGRGDK VRFTADKAKL HLFDTNGQSY
RA
