ID   AGLR_RHIME              Reviewed;         356 AA.
AC   Q9Z3R4;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   02-NOV-2001, sequence version 2.
DT   25-MAY-2022, entry version 123.
DE   RecName: Full=HTH-type transcriptional regulator AglR;
GN   Name=aglR; OrderedLocusNames=R00694; ORFNames=SMc03060;
OS   Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS   meliloti).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=266834;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=10400573; DOI=10.1128/jb.181.14.4176-4184.1999;
RA   Willis L.B., Walker G.C.;
RT   "A novel Sinorhizobium meliloti operon encodes an alpha-glucosidase and a
RT   periplasmic-binding-protein-dependent transport system for alpha-
RT   glucosides.";
RL   J. Bacteriol. 181:4176-4184(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11481430; DOI=10.1073/pnas.161294398;
RA   Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA   Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA   Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA   Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA   Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT   "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT   meliloti strain 1021.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11474104; DOI=10.1126/science.1060966;
RA   Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA   Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA   Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA   Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA   Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA   Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA   Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA   Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA   Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA   Wong K., Yeh K.-C., Batut J.;
RT   "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL   Science 293:668-672(2001).
CC   -!- FUNCTION: Probable regulatory protein for the binding-protein-dependent
CC       transport system for alpha-glucosides such as sucrose, maltose and
CC       trehalose.
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DR   EMBL; AF045609; AAD12051.1; -; Genomic_DNA.
DR   EMBL; AL591688; CAC45266.1; -; Genomic_DNA.
DR   RefSeq; NP_384800.1; NC_003047.1.
DR   RefSeq; WP_010968755.1; NC_003047.1.
DR   AlphaFoldDB; Q9Z3R4; -.
DR   SMR; Q9Z3R4; -.
DR   STRING; 266834.SMc03060; -.
DR   EnsemblBacteria; CAC45266; CAC45266; SMc03060.
DR   GeneID; 61602161; -.
DR   KEGG; sme:SMc03060; -.
DR   PATRIC; fig|266834.11.peg.2068; -.
DR   eggNOG; COG1609; Bacteria.
DR   HOGENOM; CLU_037628_6_1_5; -.
DR   OMA; DIENAFF; -.
DR   Proteomes; UP000001976; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd01392; HTH_LacI; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   InterPro; IPR000843; HTH_LacI.
DR   InterPro; IPR046335; LacI/GalR-like_sensor.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   Pfam; PF00356; LacI; 1.
DR   Pfam; PF13377; Peripla_BP_3; 1.
DR   SMART; SM00354; HTH_LACI; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   SUPFAM; SSF53822; SSF53822; 1.
DR   PROSITE; PS50932; HTH_LACI_2; 1.
PE   4: Predicted;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..356
FT                   /note="HTH-type transcriptional regulator AglR"
FT                   /id="PRO_0000107922"
FT   DOMAIN          1..57
FT                   /note="HTH lacI-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00111"
FT   DNA_BIND        5..24
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00111"
FT   REGION          337..356
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        310
FT                   /note="R -> P (in Ref. 1; AAD12051)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        327
FT                   /note="W -> G (in Ref. 1; AAD12051)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        342..356
FT                   /note="Missing (in Ref. 1; AAD12051)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   356 AA;  38525 MW;  3B7E4EB083A68C8C CRC64;
     MPVNLKQLAE LLGLSQTTVS RALNGYPEVN AETRARVLEA VRETGYRPNR AAQRLATGKA
     YSIGLVMPIA AGIDSDIHFG EFLAGLAEEA VEHDFHFVLN PSAPEDEEAT FRRLAASGNV
     DAVFIAYMRA NDPRIEMLKA LSIPFVVHGR SIGGPRDYPF VDVDNTGAFY DAARLLIQLG
     HNRIALINGP EHLTFSIRRR KGLVRALAEK GLNLDDALVH HSAMTDEHGY RSMQRFLKRP
     APPTAVLCSS TVLALGAVRA INQAGLAIGT DISLIAHDDV LPMLKPENFS VPLTTTRSSL
     RAAGARIAKR LIGGILNQGD YPEQELWRAE LIVRASTGPA PDRSPLPNPS PQVGGA