ID   ENRN_BPT3               Reviewed;         152 AA.
AC   P20314;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   29-SEP-2021, entry version 82.
DE   RecName: Full=Endodeoxyribonuclease 1;
DE            EC=3.1.21.2;
DE   AltName: Full=Endodeoxyribonuclease I;
DE            Short=Endonuclease;
GN   Name=3;
OS   Enterobacteria phage T3 (Bacteriophage T3).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Autographiviridae; Studiervirinae; Teetrevirus;
OC   Escherichia virus T3.
OX   NCBI_TaxID=10759;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Luria;
RX   PubMed=2614843; DOI=10.1016/0022-2836(89)90102-2;
RA   Beck P.J., Gonzalez S., Ward C.L., Molineux I.J.;
RT   "Sequence of bacteriophage T3 DNA from gene 2.5 through gene 9.";
RL   J. Mol. Biol. 210:687-701(1989).
CC   -!- FUNCTION: Endodeoxyribonuclease I, which is expressed in the late
CC       stage, is necessary for T3 genetic recombination and the breakdown of
CC       host DNA. In the early stage of infection, T3 DNA replicates as a
CC       linear monomer. In the late stage, the T3 DNA replicates via linear
CC       concatemers several genomes in length. The gene 3 product has also been
CC       implicated in the maturation of these concatemers.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endonucleolytic cleavage to 5'-phosphooligonucleotide end-
CC         products.; EC=3.1.21.2;
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DR   EMBL; X17255; CAA35132.1; -; Genomic_DNA.
DR   PIR; S07505; S07505.
DR   RefSeq; NP_523312.1; NC_003298.1.
DR   SMR; P20314; -.
DR   GeneID; 927412; -.
DR   KEGG; vg:927412; -.
DR   GO; GO:0008833; F:deoxyribonuclease IV (phage-T4-induced) activity; IEA:UniProtKB-EC.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; IEA:InterPro.
DR   InterPro; IPR008029; Phage_T7_Gp3_endoDNaseI.
DR   InterPro; IPR011335; Restrct_endonuc-II-like.
DR   Pfam; PF05367; Phage_endo_I; 1.
DR   SUPFAM; SSF52980; SSF52980; 1.
PE   4: Predicted;
KW   Endonuclease; Hydrolase; Nuclease.
FT   CHAIN           1..152
FT                   /note="Endodeoxyribonuclease 1"
FT                   /id="PRO_0000106485"
SQ   SEQUENCE   152 AA;  17432 MW;  BFCDE82A4C0D611B CRC64;
     MAGAYAARCT QGRAFRSGLE DKVSKQLESK GIKFDYELWR IPYVIPESDH LYTPDFLLPN
     GIFIETKGLW DSDDRKKHLL IREQHPELDI RLVFSSSRSK LYKGSPTSYG EWCEKHGILF
     ADKLIPVAGV KEPKKEVPFD KFKTKKGVKK NG