ID   ENTIC_APLCA             Reviewed;          88 AA.
AC   Q8I817;
DT   04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 32.
DE   RecName: Full=Enticin;
DE   Flags: Precursor;
OS   Aplysia californica (California sea hare).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Tectipleura; Aplysiida; Aplysioidea;
OC   Aplysiidae; Aplysia.
OX   NCBI_TaxID=6500;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, SUBCELLULAR LOCATION, AND INTERACTION
RP   WITH ATTRACTIN AND TEMPTIN.
RC   TISSUE=Albumen gland;
RX   PubMed=15054104; DOI=10.1074/jbc.m313585200;
RA   Cummins S.F., Nichols A.E., Amare A., Hummon A.B., Sweedler J.V.,
RA   Nagle G.T.;
RT   "Characterization of Aplysia enticin and temptin, two novel water-borne
RT   protein pheromones that act in concert with attractin to stimulate mate
RT   attraction.";
RL   J. Biol. Chem. 279:25614-25622(2004).
RN   [2]
RP   PROTEIN SEQUENCE OF 20-88, DICHROISM ANALYSIS, DISULFIDE BONDS, AND MASS
RP   SPECTROMETRY.
RX   PubMed=17141371; DOI=10.1016/j.peptides.2006.08.027;
RA   Cummins S.F., Xie F., Misra M., Amare A., Jakubowski J.A., de Vries M.R.,
RA   Sweedler J.V., Nagle G.T., Schein C.H.;
RT   "Recombinant production and structural studies of the Aplysia water-borne
RT   protein pheromone enticin indicates it has a novel disulfide stabilized
RT   fold.";
RL   Peptides 28:94-102(2007).
CC   -!- FUNCTION: A component of the complex of water-borne protein pheromones
CC       that stimulates attraction and mating behavior.
CC       {ECO:0000269|PubMed:15054104}.
CC   -!- SUBUNIT: Binds to attractin and temptin.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:15054104}.
CC   -!- MASS SPECTROMETRY: Mass=5307.3; Mass_error=7.0; Method=Electrospray;
CC       Evidence={ECO:0000269|PubMed:17141371};
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DR   EMBL; AY162291; AAN83923.1; -; mRNA.
DR   RefSeq; NP_001191527.1; NM_001204598.1.
DR   AlphaFoldDB; Q8I817; -.
DR   GeneID; 100533299; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005186; F:pheromone activity; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Pheromone; Secreted; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000269|PubMed:17141371"
FT   PEPTIDE         20..68
FT                   /note="Enticin"
FT                   /id="PRO_0000311915"
FT   PROPEP          69..88
FT                   /id="PRO_0000311916"
FT   DISULFID        25..33
FT                   /evidence="ECO:0000269|PubMed:17141371"
FT   DISULFID        40..52
FT                   /evidence="ECO:0000269|PubMed:17141371"
FT   DISULFID        59..67
FT                   /evidence="ECO:0000269|PubMed:17141371"
SQ   SEQUENCE   88 AA;  9666 MW;  052AFB90F544BC7A CRC64;
     MKTALPLLLL TCLVAAVQST GSQGCPTYVS EKCTARLQEC SNNQQQEPLQ NCTAVHADCV
     VQATEDCQRE QSQLNHDHLN NHTTTQQP