ID   3MGH_AERPE              Reviewed;         194 AA.
AC   Q9Y9P1;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Putative 3-methyladenine DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_00527};
DE            EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_00527};
GN   OrderedLocusNames=APE_2247;
OS   Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 /
OS   K1).
OC   Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales;
OC   Desulfurococcaceae; Aeropyrum.
OX   NCBI_TaxID=272557;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1;
RX   PubMed=10382966; DOI=10.1093/dnares/6.2.83;
RA   Kawarabayasi Y., Hino Y., Horikawa H., Yamazaki S., Haikawa Y., Jin-no K.,
RA   Takahashi M., Sekine M., Baba S., Ankai A., Kosugi H., Hosoyama A.,
RA   Fukui S., Nagai Y., Nishijima K., Nakazawa H., Takamiya M., Masuda S.,
RA   Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A.,
RA   Aoki K., Kubota K., Nakamura Y., Nomura N., Sako Y., Kikuchi H.;
RT   "Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon,
RT   Aeropyrum pernix K1.";
RL   DNA Res. 6:83-101(1999).
CC   -!- SIMILARITY: Belongs to the DNA glycosylase MPG family.
CC       {ECO:0000255|HAMAP-Rule:MF_00527}.
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DR   EMBL; BA000002; BAA81259.1; -; Genomic_DNA.
DR   PIR; C72450; C72450.
DR   AlphaFoldDB; Q9Y9P1; -.
DR   SMR; Q9Y9P1; -.
DR   STRING; 272557.APE_2247; -.
DR   EnsemblBacteria; BAA81259; BAA81259; APE_2247.
DR   KEGG; ape:APE_2247; -.
DR   eggNOG; arCOG04295; Archaea.
DR   OMA; IEVEPYF; -.
DR   Proteomes; UP000002518; Chromosome.
DR   GO; GO:0003905; F:alkylbase DNA N-glycosylase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   CDD; cd00540; AAG; 1.
DR   Gene3D; 3.10.300.10; -; 2.
DR   HAMAP; MF_00527; 3MGH; 1.
DR   InterPro; IPR011034; Formyl_transferase-like_C_sf.
DR   InterPro; IPR003180; MPG.
DR   InterPro; IPR036995; MPG_sf.
DR   PANTHER; PTHR10429; PTHR10429; 2.
DR   Pfam; PF02245; Pur_DNA_glyco; 1.
DR   SUPFAM; SSF50486; SSF50486; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; Hydrolase; Reference proteome.
FT   CHAIN           1..194
FT                   /note="Putative 3-methyladenine DNA glycosylase"
FT                   /id="PRO_0000100117"
SQ   SEQUENCE   194 AA;  21276 MW;  1EE737DC6A1406EE CRC64;
     MGRLLPKSFY YRQPDVVARE LLGKILVSCA SGACMRCMVT EAEAYFGECD PASRARRGRG
     RIWRALYGEP GRALVYGMHR QWLLNIVAHS EGMAGAVLLR SCQPLEPPRL DPPPIGPGRL
     ARALSIDRGV DGAPVYERGS PLTLWENPEA VEGFRVACSG RVGVSEDLEL PLRFYIAGNP
     FVSKARVSPA PKHC