AGMR_PSEAE
ID AGMR_PSEAE Reviewed; 221 AA.
AC P29369;
DT 01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-1992, sequence version 1.
DT 03-AUG-2022, entry version 138.
DE RecName: Full=Glycerol metabolism activator;
DE AltName: Full=Protein AgmR;
GN Name=agmR; Synonyms=glpR; OrderedLocusNames=PA1978;
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=1938886; DOI=10.1128/jb.173.21.6798-6806.1991;
RA Schweizer H.P.;
RT "The agmR gene, an environmentally responsive gene, complements defective
RT glpR, which encodes the putative activator for glycerol metabolism in
RT Pseudomonas aeruginosa.";
RL J. Bacteriol. 173:6798-6806(1991).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- FUNCTION: Positive activator for glycerol metabolism.
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DR EMBL; M60805; AAA25827.1; -; Genomic_DNA.
DR EMBL; AE004091; AAG05366.1; -; Genomic_DNA.
DR PIR; A41333; A41333.
DR RefSeq; NP_250668.1; NC_002516.2.
DR RefSeq; WP_003107754.1; NZ_QZGE01000030.1.
DR AlphaFoldDB; P29369; -.
DR SMR; P29369; -.
DR STRING; 287.DR97_5870; -.
DR PaxDb; P29369; -.
DR PRIDE; P29369; -.
DR DNASU; 880879; -.
DR EnsemblBacteria; AAG05366; AAG05366; PA1978.
DR GeneID; 880879; -.
DR KEGG; pae:PA1978; -.
DR PATRIC; fig|208964.12.peg.2061; -.
DR PseudoCAP; PA1978; -.
DR HOGENOM; CLU_000445_90_8_6; -.
DR InParanoid; P29369; -.
DR OMA; HNVISDG; -.
DR PhylomeDB; P29369; -.
DR BioCyc; PAER208964:G1FZ6-2016-MON; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006071; P:glycerol metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR CDD; cd06170; LuxR_C_like; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR Pfam; PF00196; GerE; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00038; HTHLUXR.
DR SMART; SM00421; HTH_LUXR; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF46894; SSF46894; 1.
DR SUPFAM; SSF52172; SSF52172; 1.
DR PROSITE; PS00622; HTH_LUXR_1; 1.
DR PROSITE; PS50043; HTH_LUXR_2; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 3: Inferred from homology;
KW Activator; DNA-binding; Glycerol metabolism; Phosphoprotein;
KW Reference proteome; Transcription; Transcription regulation;
KW Two-component regulatory system.
FT CHAIN 1..221
FT /note="Glycerol metabolism activator"
FT /id="PRO_0000080994"
FT DOMAIN 3..120
FT /note="Response regulatory"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT DOMAIN 149..214
FT /note="HTH luxR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
FT DNA_BIND 173..192
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
FT MOD_RES 55
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 221 AA; 24424 MW; 1366B243D18B72C7 CRC64;
MYKILIADDH PLFREAIHNV IADGFPGSEV METADLDSAL GLTQEHDDLD LILLDLNMPG
MHGLNGLMNL RNEAPTIPVV IVSAEQDKQV VLQAITYGAV GFITKSSPRA QMTEAIEQIL
NGNVYLPSDV IRTQKSSPRR SGHEEHGISP ELLQALTRKQ LLVLERMTKG ESNKQIAYNL
DIAETTVKAH VSAILRKLKV HNRVQAILSA GDIDFAAYLR R
