ENTS_CITK8
ID ENTS_CITK8 Reviewed; 416 AA.
AC A8AJL6;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 23-OCT-2007, sequence version 1.
DT 03-AUG-2022, entry version 85.
DE RecName: Full=Enterobactin exporter EntS {ECO:0000255|HAMAP-Rule:MF_01436};
GN Name=entS {ECO:0000255|HAMAP-Rule:MF_01436}; OrderedLocusNames=CKO_02570;
OS Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Citrobacter.
OX NCBI_TaxID=290338;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-895 / CDC 4225-83 / SGSC4696;
RG The Citrobacter koseri Genome Sequencing Project;
RA McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S.,
RA Latreille P., Courtney L., Wang C., Pepin K., Bhonagiri V., Nash W.,
RA Johnson M., Thiruvilangam P., Wilson R.;
RL Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of an export pathway for enterobactin.
CC {ECO:0000255|HAMAP-Rule:MF_01436}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01436}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01436}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. EntS (TC
CC 2.A.1.38) family. {ECO:0000255|HAMAP-Rule:MF_01436}.
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DR EMBL; CP000822; ABV13679.1; -; Genomic_DNA.
DR RefSeq; WP_012133398.1; NC_009792.1.
DR AlphaFoldDB; A8AJL6; -.
DR SMR; A8AJL6; -.
DR STRING; 290338.CKO_02570; -.
DR PRIDE; A8AJL6; -.
DR EnsemblBacteria; ABV13679; ABV13679; CKO_02570.
DR GeneID; 45136441; -.
DR KEGG; cko:CKO_02570; -.
DR HOGENOM; CLU_034180_11_0_6; -.
DR OMA; MVVNIPM; -.
DR OrthoDB; 460405at2; -.
DR Proteomes; UP000008148; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0042931; F:enterobactin transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; -; 1.
DR HAMAP; MF_01436; MFS_EntS; 1.
DR InterPro; IPR023722; Enterobactin_exp_EntS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR010290; TM_effector.
DR Pfam; PF05977; MFS_3; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..416
FT /note="Enterobactin exporter EntS"
FT /id="PRO_1000017365"
FT TOPO_DOM 1..21
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TRANSMEM 22..42
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TOPO_DOM 43..55
FT /note="Periplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TRANSMEM 56..76
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TOPO_DOM 77..83
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TRANSMEM 84..104
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TOPO_DOM 105..109
FT /note="Periplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TRANSMEM 110..130
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TOPO_DOM 131..156
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TRANSMEM 157..177
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TOPO_DOM 178
FT /note="Periplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TRANSMEM 179..199
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TOPO_DOM 200..218
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TRANSMEM 219..239
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TOPO_DOM 240..256
FT /note="Periplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TRANSMEM 257..277
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TOPO_DOM 278..287
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TRANSMEM 288..307
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TOPO_DOM 308..313
FT /note="Periplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TRANSMEM 314..336
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TOPO_DOM 337..356
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TRANSMEM 357..377
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TOPO_DOM 378
FT /note="Periplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TRANSMEM 379..399
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TOPO_DOM 400..416
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
SQ SEQUENCE 416 AA; 43273 MW; CA711AFA40AAFC84 CRC64;
MNRQSWLLNL SLLKTHPAFR AVFLARFISI VSLGLLGVAV PVQIQMMTHS TWQVGLSVTL
TGSAMFVGLM VGGVLADRYE RKKVILLARG TCGIGFIGLC LNALLPEPSL LAIYLLGLWD
GFFASLGVTA LLAATPALVG RENLMQAGAI TMLTVRLGSV ISPMLGGVLL ATGGVAWNYG
LAAAGTFITL LPLLSLPALP PPPQPREHPL KSLLAAFRFL LSSPLIGGIA LLGGLLTMAS
AVRVLYPALA INWHMSAAQI GLLYAAIPLG AAVGALTSGQ LAHSVRPGLL MLVSTVGSFL
AIGVFGLMPV WLLGVICLAL FGWLSAISSL LQYTLLQTQT PEAMLGRING LWTAQNVTGD
AIGAALLGGL GAMMTPVASA SVSGFGLVIV GLLLMLLLGE LRRFRQPPPV PDGAPL