位置:首页 > 蛋白库 > AGN10_PAEDI
AGN10_PAEDI
ID   AGN10_PAEDI             Reviewed;         404 AA.
AC   A0A411PQP1;
DT   26-FEB-2020, integrated into UniProtKB/Swiss-Prot.
DT   08-MAY-2019, sequence version 1.
DT   25-MAY-2022, entry version 11.
DE   RecName: Full=Agnestins biosynthesis cluster transcription factor AgnL10 {ECO:0000303|PubMed:30746079};
DE   AltName: Full=Agnestins biosynthesis cluster protein L10 {ECO:0000303|PubMed:30746079};
GN   Name=Agn10 {ECO:0000303|PubMed:30746079};
OS   Paecilomyces divaricatus (Penicillium divaricatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Thermoascaceae; Paecilomyces.
OX   NCBI_TaxID=644132;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RC   STRAIN=K5013;
RX   PubMed=30746079; DOI=10.1039/c8sc03778g;
RA   Szwalbe A.J., Williams K., Song Z., de Mattos-Shipley K., Vincent J.L.,
RA   Bailey A.M., Willis C.L., Cox R.J., Simpson T.J.;
RT   "Characterisation of the biosynthetic pathway to agnestins A and B reveals
RT   the reductive route to chrysophanol in fungi.";
RL   Chem. Sci. 10:233-238(2019).
CC   -!- FUNCTION: Transcription factor that regulates the expression of the
CC       gene cluster that mediates the biosynthesis of agnestins, dihydroxy-
CC       xanthone metabolites. {ECO:0000269|PubMed:30746079}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; MH898872; QBG38878.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A411PQP1; -.
DR   SMR; A0A411PQP1; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045122; P:aflatoxin biosynthetic process; IEA:InterPro.
DR   CDD; cd00067; GAL4; 1.
DR   Gene3D; 4.10.240.10; -; 1.
DR   InterPro; IPR013700; AflR.
DR   InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   Pfam; PF08493; AflR; 1.
DR   Pfam; PF00172; Zn_clus; 1.
DR   SMART; SM00066; GAL4; 1.
DR   SUPFAM; SSF57701; SSF57701; 1.
DR   PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Transcription;
KW   Transcription regulation; Zinc.
FT   CHAIN           1..404
FT                   /note="Agnestins biosynthesis cluster transcription factor
FT                   AgnL10"
FT                   /id="PRO_0000449022"
FT   DNA_BIND        23..50
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT   REGION          54..83
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          188..209
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          294..318
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        68..83
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   404 AA;  43424 MW;  EBEDA911C80FE84C CRC64;
     MQFPLASAHE DSPPAGLKLR DSCNRCAVSK IKCSKEKPAC ARCAKQDKVC EYSATKRAGR
     KRGSRRHNNP VPSPTTQDLP TAAPSTCPTF LEDPETIPLS PRPPFESYPD LFPGIFSIGD
     DPLIATPITL DTFSFPFDSF SASPISLPTL DVSDGDHLPD AVPLNHLNHP GDRTDVARAT
     ALLASDHASA SSMDPAAGPQ RPPDEPSSGP ICGFIRALGL LNGLSSPAWP TSHHPGLDPR
     PSSRSIMAEN EQTVRAISEM LHCQCFDDGY LLAILSMLIL KVLSSYATLL RQTPGPDGDG
     VSWDNSTPPP GEQGAGVDGE DHCRTIAQQI LGQLHRVQRL VSILSQRFNI PGGRARTPDS
     TAGPDLLSSI ETLFPVPGSM LEQMEGLLRK RLRTLSAEIV DILR
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024