ENTS_ECOL6
ID ENTS_ECOL6 Reviewed; 416 AA.
AC Q8FK20;
DT 21-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=Enterobactin exporter EntS {ECO:0000255|HAMAP-Rule:MF_01436};
GN Name=entS {ECO:0000255|HAMAP-Rule:MF_01436}; OrderedLocusNames=c0678;
OS Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=199310;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CFT073 / ATCC 700928 / UPEC;
RX PubMed=12471157; DOI=10.1073/pnas.252529799;
RA Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA Donnenberg M.S., Blattner F.R.;
RT "Extensive mosaic structure revealed by the complete genome sequence of
RT uropathogenic Escherichia coli.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC -!- FUNCTION: Component of an export pathway for enterobactin.
CC {ECO:0000255|HAMAP-Rule:MF_01436}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01436}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01436}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. EntS (TC
CC 2.A.1.38) family. {ECO:0000255|HAMAP-Rule:MF_01436}.
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DR EMBL; AE014075; AAN79153.1; -; Genomic_DNA.
DR RefSeq; WP_001041793.1; NC_004431.1.
DR AlphaFoldDB; Q8FK20; -.
DR SMR; Q8FK20; -.
DR STRING; 199310.c0678; -.
DR EnsemblBacteria; AAN79153; AAN79153; c0678.
DR KEGG; ecc:c0678; -.
DR eggNOG; COG0477; Bacteria.
DR HOGENOM; CLU_034180_11_0_6; -.
DR OMA; TPDDMRG; -.
DR BioCyc; ECOL199310:C0678-MON; -.
DR Proteomes; UP000001410; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0042931; F:enterobactin transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; -; 1.
DR HAMAP; MF_01436; MFS_EntS; 1.
DR InterPro; IPR023722; Enterobactin_exp_EntS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR010290; TM_effector.
DR Pfam; PF05977; MFS_3; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..416
FT /note="Enterobactin exporter EntS"
FT /id="PRO_0000227650"
FT TOPO_DOM 1..21
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TRANSMEM 22..42
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TOPO_DOM 43..55
FT /note="Periplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TRANSMEM 56..76
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TOPO_DOM 77..83
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TRANSMEM 84..104
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TOPO_DOM 105..109
FT /note="Periplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TRANSMEM 110..130
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TOPO_DOM 131..156
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TRANSMEM 157..177
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TOPO_DOM 178
FT /note="Periplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TRANSMEM 179..199
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TOPO_DOM 200..218
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TRANSMEM 219..239
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TOPO_DOM 240..256
FT /note="Periplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TRANSMEM 257..277
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TOPO_DOM 278..287
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TRANSMEM 288..307
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TOPO_DOM 308..313
FT /note="Periplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TRANSMEM 314..336
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TOPO_DOM 337..356
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TRANSMEM 357..377
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TOPO_DOM 378
FT /note="Periplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TRANSMEM 379..399
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
FT TOPO_DOM 400..416
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01436"
SQ SEQUENCE 416 AA; 43313 MW; E6EE449770992DA5 CRC64;
MNKQSWLLNL SLLKTHPAFR AVFLARFISI VSLGLLGVAV PVQIQMMTHS TWQVGLSVTL
TGGAMFVGLM VGGVLADRYE RKKVILLARG TCGIGFIGLC LNALLPEPSL LAIYLLGLWD
GFFASLGVTA LLAATPALVG RENLMQAGAI TMLTVRLGSV ISPMIGGLLL ATGGVAWNYG
LAAAGTFITL LPLLSLPALP PPPQPREHPL KSLLAGFRFL LASPLVGGIA LLGGLLTMAS
AVRVLYPALA DNWQMSAAQI GFLYAAIPLG AAIGALTSGK LAHSVRPGLL MLLSTLGAFL
AIGLFGLMPM WILGVVCLAL FGWLSAVSSL LQYTMLQTQT PEAMLGRING LWTAQNVTGD
AIGAALLGGL GAMMTPVASA SASGFGLLII GVLLLLVLVE LRRFRQTPPQ VTASDS
