ENV2_MOUSE
ID ENV2_MOUSE Reviewed; 679 AA.
AC P11370; Q61529;
DT 01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT 10-JAN-2003, sequence version 2.
DT 25-MAY-2022, entry version 104.
DE RecName: Full=Retrovirus-related Env polyprotein from Fv-4 locus;
GN Name=Fv4; Synonyms=Env;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=BALB/cJ; TISSUE=Liver;
RX PubMed=2304138; DOI=10.1128/jvi.64.3.1033-1043.1990;
RA Masuda M., Yoshikura H.;
RT "Construction and characterization of the recombinant Moloney murine
RT leukemia viruses bearing the mouse Fv-4 env gene.";
RL J. Virol. 64:1033-1043(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-348 AND 595-679.
RX PubMed=2991595; DOI=10.1128/jvi.55.3.768-777.1985;
RA Ikeda H., Laigret F., Martin M.A., Repaske R.;
RT "Characterization of a molecularly cloned retroviral sequence associated
RT with Fv-4 resistance.";
RL J. Virol. 55:768-777(1985).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Spleen;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
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DR EMBL; M33884; AAA37564.1; -; Genomic_DNA.
DR EMBL; M11051; AAA37562.1; -; Genomic_DNA.
DR EMBL; M11052; AAA37563.1; -; Genomic_DNA.
DR PIR; A25483; A25483.
DR AlphaFoldDB; P11370; -.
DR SMR; P11370; -.
DR IntAct; P11370; 1.
DR iPTMnet; P11370; -.
DR PhosphoSitePlus; P11370; -.
DR SwissPalm; P11370; -.
DR jPOST; P11370; -.
DR MaxQB; P11370; -.
DR PeptideAtlas; P11370; -.
DR PRIDE; P11370; -.
DR ProteomicsDB; 275460; -.
DR MGI; MGI:95598; Fv4.
DR InParanoid; P11370; -.
DR PRO; PR:P11370; -.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; P11370; protein.
DR Gene3D; 3.90.310.10; -; 1.
DR InterPro; IPR008981; FMuLV_rcpt-bd.
DR InterPro; IPR018154; TLV/ENV_coat_polyprotein.
DR PANTHER; PTHR10424; PTHR10424; 1.
DR Pfam; PF00429; TLV_coat; 1.
DR SUPFAM; SSF49830; SSF49830; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..679
FT /note="Retrovirus-related Env polyprotein from Fv-4 locus"
FT /id="PRO_0000086983"
FT REGION 268..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 273..311
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 299
FT /note="D -> T (in Ref. 2)"
FT /evidence="ECO:0000305"
FT CONFLICT 301..302
FT /note="LT -> SL (in Ref. 2)"
FT /evidence="ECO:0000305"
FT CONFLICT 305
FT /note="T -> R (in Ref. 2)"
FT /evidence="ECO:0000305"
FT CONFLICT 307
FT /note="D -> P (in Ref. 2)"
FT /evidence="ECO:0000305"
FT CONFLICT 309..320
FT /note="LTPTKPPQAGTG -> HSHQTSTGGDR (in Ref. 2)"
FT /evidence="ECO:0000305"
FT CONFLICT 595
FT /note="R -> K (in Ref. 2)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 679 AA; 74453 MW; 5242BD0D86554039 CRC64;
MESPAFSKPL KDKTIKKALL GVLGILLVTG GLAHKDSPHL IYNLTWEVTN GEQETVWAVT
GNHPLWTWWP DLTPDLCMLA LHGPTHWGLD NRPPYSSPPG PPCCSGDKGA VSGCARDCDE
PLTSYSPRCN TAWNRMKLAQ VTHAPKEGFY VCPGSHRPRW ARSCGGPEAY YCASWGCETT
GRAAWKPTSS WDYITVSNNL SSPQAPKACK NNGWCNPLVV RFTGPGKRAT SWTTGHEWGL
RLYISGHDPG LTFGIRLRIT DLGPRVPIGP NPVLSDQRPP SRPVPARPPP PSNSTPTGDP
LTPPTGDPLT PTKPPQAGTG DRLLNLVQGA YLALNMTNPT KTQECWLCLV SEPPYYEGVA
VLGDYTKHET APTNCSSRAQ HKLTLSEVTG QGKCLGAVPK THQALCNHTE PTVSGSNYLV
APEGTLWACS TGLTPCLSTT VLNLTTDYCV LVELWPKVTY HPSEYVYTQF EPGVRFRREP
VSLTLALLLG GLTMGGIAAR VGTGTTALVA TQQFQQLQAA MHNDLKAVEE SITNLERSLT
SLSEVVLQNR RGLDLLFLKE GGLCAALKEE CCFYADHTGL VRDSMAKLRE RLNQRQKLFE
SGQGWFEGLF NRSPWFTTLI STIMGPLIVL LLILLFGPCI LNRLVQFVKD RISVVQALIL
TQQYHQLKSI DPEEVESRE