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ENV2_MOUSE
ID   ENV2_MOUSE              Reviewed;         679 AA.
AC   P11370; Q61529;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   10-JAN-2003, sequence version 2.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=Retrovirus-related Env polyprotein from Fv-4 locus;
GN   Name=Fv4; Synonyms=Env;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=BALB/cJ; TISSUE=Liver;
RX   PubMed=2304138; DOI=10.1128/jvi.64.3.1033-1043.1990;
RA   Masuda M., Yoshikura H.;
RT   "Construction and characterization of the recombinant Moloney murine
RT   leukemia viruses bearing the mouse Fv-4 env gene.";
RL   J. Virol. 64:1033-1043(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-348 AND 595-679.
RX   PubMed=2991595; DOI=10.1128/jvi.55.3.768-777.1985;
RA   Ikeda H., Laigret F., Martin M.A., Repaske R.;
RT   "Characterization of a molecularly cloned retroviral sequence associated
RT   with Fv-4 resistance.";
RL   J. Virol. 55:768-777(1985).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Spleen;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
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DR   EMBL; M33884; AAA37564.1; -; Genomic_DNA.
DR   EMBL; M11051; AAA37562.1; -; Genomic_DNA.
DR   EMBL; M11052; AAA37563.1; -; Genomic_DNA.
DR   PIR; A25483; A25483.
DR   AlphaFoldDB; P11370; -.
DR   SMR; P11370; -.
DR   IntAct; P11370; 1.
DR   iPTMnet; P11370; -.
DR   PhosphoSitePlus; P11370; -.
DR   SwissPalm; P11370; -.
DR   jPOST; P11370; -.
DR   MaxQB; P11370; -.
DR   PeptideAtlas; P11370; -.
DR   PRIDE; P11370; -.
DR   ProteomicsDB; 275460; -.
DR   MGI; MGI:95598; Fv4.
DR   InParanoid; P11370; -.
DR   PRO; PR:P11370; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; P11370; protein.
DR   Gene3D; 3.90.310.10; -; 1.
DR   InterPro; IPR008981; FMuLV_rcpt-bd.
DR   InterPro; IPR018154; TLV/ENV_coat_polyprotein.
DR   PANTHER; PTHR10424; PTHR10424; 1.
DR   Pfam; PF00429; TLV_coat; 1.
DR   SUPFAM; SSF49830; SSF49830; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..679
FT                   /note="Retrovirus-related Env polyprotein from Fv-4 locus"
FT                   /id="PRO_0000086983"
FT   REGION          268..321
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        273..311
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        299
FT                   /note="D -> T (in Ref. 2)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        301..302
FT                   /note="LT -> SL (in Ref. 2)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        305
FT                   /note="T -> R (in Ref. 2)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        307
FT                   /note="D -> P (in Ref. 2)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        309..320
FT                   /note="LTPTKPPQAGTG -> HSHQTSTGGDR (in Ref. 2)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        595
FT                   /note="R -> K (in Ref. 2)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   679 AA;  74453 MW;  5242BD0D86554039 CRC64;
     MESPAFSKPL KDKTIKKALL GVLGILLVTG GLAHKDSPHL IYNLTWEVTN GEQETVWAVT
     GNHPLWTWWP DLTPDLCMLA LHGPTHWGLD NRPPYSSPPG PPCCSGDKGA VSGCARDCDE
     PLTSYSPRCN TAWNRMKLAQ VTHAPKEGFY VCPGSHRPRW ARSCGGPEAY YCASWGCETT
     GRAAWKPTSS WDYITVSNNL SSPQAPKACK NNGWCNPLVV RFTGPGKRAT SWTTGHEWGL
     RLYISGHDPG LTFGIRLRIT DLGPRVPIGP NPVLSDQRPP SRPVPARPPP PSNSTPTGDP
     LTPPTGDPLT PTKPPQAGTG DRLLNLVQGA YLALNMTNPT KTQECWLCLV SEPPYYEGVA
     VLGDYTKHET APTNCSSRAQ HKLTLSEVTG QGKCLGAVPK THQALCNHTE PTVSGSNYLV
     APEGTLWACS TGLTPCLSTT VLNLTTDYCV LVELWPKVTY HPSEYVYTQF EPGVRFRREP
     VSLTLALLLG GLTMGGIAAR VGTGTTALVA TQQFQQLQAA MHNDLKAVEE SITNLERSLT
     SLSEVVLQNR RGLDLLFLKE GGLCAALKEE CCFYADHTGL VRDSMAKLRE RLNQRQKLFE
     SGQGWFEGLF NRSPWFTTLI STIMGPLIVL LLILLFGPCI LNRLVQFVKD RISVVQALIL
     TQQYHQLKSI DPEEVESRE
 
 
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