ID   AGNO_POVSM              Reviewed;          70 AA.
AC   A8Y986;
DT   16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   29-SEP-2021, entry version 34.
DE   RecName: Full=Squirrel monkey agnoprotein;
DE   AltName: Full=Agno;
GN   Name=agnogene;
OS   Squirrel monkey polyomavirus.
OC   Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes;
OC   Sepolyvirales; Polyomaviridae; Betapolyomavirus.
OX   NCBI_TaxID=452475;
OH   NCBI_TaxID=39432; Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Squi0106;
RX   PubMed=18089736; DOI=10.1099/vir.0.83287-0;
RA   Verschoor E.J., Groenewoud M.J., Fagrouch Z., Kewalapat A., van Gessel S.,
RA   Kik M.J., Heeney J.L.;
RT   "Molecular characterization of the first polyomavirus from a New World
RT   primate: squirrel monkey polyomavirus.";
RL   J. Gen. Virol. 89:130-137(2008).
CC   -!- FUNCTION: Alters the structure of the nuclear envelope. Involved in the
CC       perinuclear-nuclear localization of the capsid protein VP1 during
CC       virion assembly and maturation. May contribute to viral genome
CC       transcription and translation of viral late proteins. Plays an
CC       important role in the release of progeny virions from infected cells
CC       and in viral propagation (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with VP1. Interacts with Large T antigen. Interacts
CC       with small t antigen. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm. Host nucleus {ECO:0000250}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing, Alternative initiation; Named isoforms=5;
CC       Name=Agno;
CC         IsoId=A8Y986-1; Sequence=Displayed;
CC       Name=VP1; Synonyms=Major capsid protein VP1;
CC         IsoId=A8Y983-1; Sequence=External;
CC       Name=VP2; Synonyms=Minor capsid protein VP2;
CC         IsoId=A8Y987-1; Sequence=External;
CC       Name=VP3; Synonyms=Minor capsid protein VP3;
CC         IsoId=A8Y987-2; Sequence=External;
CC       Name=VP4;
CC         IsoId=A8Y987-3; Sequence=External;
CC   -!- PTM: Phosphorylated by host PKC. Phosphorylation alters the stability
CC       and may also have an impact on the subcellular location (By
CC       similarity). {ECO:0000250}.
CC   -!- MISCELLANEOUS: [Isoform Agno]: Produced by alternative initiation of
CC       the late mRNA.
CC   -!- CAUTION: Encoded by the same late mRNA leader region, but very
CC       different from other primate polyomavirus agnoproteins. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AM748741; CAO03079.1; -; Genomic_DNA.
DR   RefSeq; YP_001531345.1; NC_009951.1. [A8Y986-1]
DR   GeneID; 5714856; -.
DR   KEGG; vg:5714856; -.
DR   Proteomes; UP000135044; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Alternative initiation; Alternative splicing; Host cytoplasm; Host nucleus;
KW   Host-virus interaction; Phosphoprotein; Reference proteome.
FT   CHAIN           1..70
FT                   /note="Squirrel monkey agnoprotein"
FT                   /id="PRO_0000356263"
SQ   SEQUENCE   70 AA;  7830 MW;  A7944ABDA43A183A CRC64;
     MARKLMARKT PPLVGLDTVQ LRVETIWLTS QMDLFVLTDK GEPRITASRA SASRVATFGM
     TSVWLKNSCF