EOS1_SCHPO
ID EOS1_SCHPO Reviewed; 209 AA.
AC Q8TFH6;
DT 23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 22-SEP-2009, sequence version 3.
DT 25-MAY-2022, entry version 88.
DE RecName: Full=N-glycosylation protein eos1;
GN Name=eos1; ORFNames=SPAPB17E12.08;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- FUNCTION: Involved in N-glycosylation. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC Multi-pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the EOS1 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CU329670; CAD27501.3; -; Genomic_DNA.
DR RefSeq; NP_001018223.3; NM_001018703.3.
DR AlphaFoldDB; Q8TFH6; -.
DR BioGRID; 280475; 2.
DR STRING; 4896.SPAPB17E12.08.1; -.
DR PaxDb; Q8TFH6; -.
DR EnsemblFungi; SPAPB17E12.08.1; SPAPB17E12.08.1:pep; SPAPB17E12.08.
DR GeneID; 3361399; -.
DR KEGG; spo:SPAPB17E12.08; -.
DR PomBase; SPAPB17E12.08; eos1.
DR VEuPathDB; FungiDB:SPAPB17E12.08; -.
DR eggNOG; ENOG502QTWB; Eukaryota.
DR HOGENOM; CLU_043059_1_0_1; -.
DR InParanoid; Q8TFH6; -.
DR OMA; AWIAISC; -.
DR PhylomeDB; Q8TFH6; -.
DR PRO; PR:Q8TFH6; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; ISO:PomBase.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0034599; P:cellular response to oxidative stress; IEA:InterPro.
DR GO; GO:0006487; P:protein N-linked glycosylation; ISO:PomBase.
DR InterPro; IPR021100; N-glycosylation_EOS1.
DR PANTHER; PTHR28147; PTHR28147; 2.
DR Pfam; PF12326; EOS1; 2.
DR PRINTS; PR02070; NGLYCOSEOS1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..209
FT /note="N-glycosylation protein eos1"
FT /id="PRO_0000350749"
FT TOPO_DOM 1..22
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 23..45
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 46..63
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 85..98
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 99..119
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 120..121
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 122..142
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 143..174
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 196..209
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 209 AA; 23737 MW; 8ADF8C2990AB442A CRC64;
MKQYLNTVIS NPRPAQALGI NQPFVVFCFI TSRALSFVPA IYWCFKCLHL AFVADKFKWL
PLTSALWTLV SAYLSFVLAN GFLLKWLIHY SIGPTIIRLF SLNVINFSFL SLSVSFITHG
DNAYLLPAWI AISCFQTAAY IVQDWITSPI IRTLPFRSSS SSSSNYRHNL DFLEITVFAV
VPVGIASFFT MVMLIWQLYK YPDSFLVSA
