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AGO11_ORYSJ
ID   AGO11_ORYSJ             Reviewed;         892 AA.
AC   Q10F39; Q7XZZ9;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   07-JUL-2009, sequence version 2.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Protein argonaute 11;
DE            Short=OsAGO11;
GN   Name=AGO11; OrderedLocusNames=Os03g0682600, LOC_Os03g47830;
GN   ORFNames=OSJNBb0070O09.7;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16109971; DOI=10.1101/gr.3869505;
RG   The rice chromosome 3 sequencing consortium;
RA   Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA   Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA   Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA   Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA   Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA   Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA   Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA   Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA   Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA   Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA   O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA   Jin W., Lee H.R., Jiang J., Jackson S.;
RT   "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT   and diverged grass species.";
RL   Genome Res. 15:1284-1291(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=18826656; DOI=10.1186/1471-2164-9-451;
RA   Kapoor M., Arora R., Lama T., Nijhawan A., Khurana J.P., Tyagi A.K.,
RA   Kapoor S.;
RT   "Genome-wide identification, organization and phylogenetic analysis of
RT   dicer-like, argonaute and RNA-dependent RNA polymerase gene families and
RT   their expression analysis during reproductive development and stress in
RT   rice.";
RL   BMC Genomics 9:451-451(2008).
CC   -!- FUNCTION: Probably involved in the RNA silencing pathway. May bind to
CC       short RNAs such as microRNAs (miRNAs) or short interfering RNAs
CC       (siRNAs), and represses the translation of mRNAs which are
CC       complementary to them (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the argonaute family. Ago subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAP68388.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=ABF98226.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=BAF12825.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AC087412; AAP68388.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; DP000009; ABF98226.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP008209; BAF12825.2; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014959; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; Q10F39; -.
DR   SMR; Q10F39; -.
DR   STRING; 4530.OS03T0682600-00; -.
DR   PaxDb; Q10F39; -.
DR   PRIDE; Q10F39; -.
DR   eggNOG; KOG1041; Eukaryota.
DR   HOGENOM; CLU_004544_4_3_1; -.
DR   InParanoid; Q10F39; -.
DR   Proteomes; UP000000763; Chromosome 3.
DR   Proteomes; UP000059680; Chromosome 3.
DR   Genevisible; Q10F39; OS.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0004521; F:endoribonuclease activity; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0035194; P:post-transcriptional gene silencing by RNA; IBA:GO_Central.
DR   CDD; cd04657; Piwi_ago-like; 1.
DR   Gene3D; 3.30.420.10; -; 1.
DR   InterPro; IPR032472; ArgoL2.
DR   InterPro; IPR032473; Argonaute_Mid_dom.
DR   InterPro; IPR032474; Argonaute_N.
DR   InterPro; IPR003100; PAZ_dom.
DR   InterPro; IPR036085; PAZ_dom_sf.
DR   InterPro; IPR003165; Piwi.
DR   InterPro; IPR045246; Piwi_ago-like.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   Pfam; PF16488; ArgoL2; 1.
DR   Pfam; PF16487; ArgoMid; 1.
DR   Pfam; PF16486; ArgoN; 1.
DR   Pfam; PF02170; PAZ; 1.
DR   Pfam; PF02171; Piwi; 1.
DR   SMART; SM00950; Piwi; 1.
DR   SUPFAM; SSF101690; SSF101690; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   PROSITE; PS50821; PAZ; 1.
DR   PROSITE; PS50822; PIWI; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; RNA-mediated gene silencing.
FT   CHAIN           1..892
FT                   /note="Protein argonaute 11"
FT                   /id="PRO_0000378434"
FT   DOMAIN          252..362
FT                   /note="PAZ"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00142"
FT   DOMAIN          541..848
FT                   /note="Piwi"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00150"
FT   REGION          1..68
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          86..117
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          850..876
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   892 AA;  98774 MW;  1B16DC9522C2B541 CRC64;
     MSSRGGGVGG RRGGPGGASS VRGGERGRKR GRGALDAVEP RVPLPRGTGS GPGAGRDGAA
     APVPALQPAE ADVLSGEVET EMAAGMEARE GASSSSSASA PAVGEVEPPS RAVGALPPTS
     SKAVVLQARP GFGTVGTSCR VRANHFVVQL ADKEIYHYDV AIAPELRSRE RNRNIINELL
     RSHKKYLDGR RSPAYDGRKG MFTAGALPFT DREFVVKIAN DPERGNQGEK EFKVTIKCAG
     AANLYMHSLK QFLAGTYPSQ DRFSHKHLDI RILIVALNGG EDISATTFYK AQPVIDFALD
     YLNMNIRDAY SRFDQDGTRV SVVQYFNRQY SYSLKYINWP CLQAGSDSRP TYLPMEVCRI
     VKGQRYSRKL NECQVTRMLR LARETPEERE NSILEIANEN NYGNDYHARE FGIGVTNQLA
     LVDARVLPAP MLKYHDSGQE KVCNPSIGQW NMNNKRMLNG GSINYWACLT FASCVRLAEV
     RTFCKELVRV CNSIGMQITG EPCVRIRQER QDHLDAAVRD IHRQSAEFLS QQGVIGQQLE
     LLVIVLPDAN ATVFYGRIKR LCETELGVIT QCCLARNVQN VGGRNTVLED ALHRRIPLLT
     DMPTMIFGAD VTHPPAGEDS SPSIAAVVAS MDWPEVSKYK CSVSSQSHRE EIIADLFTEV
     KDSQNRLVYG GMIRELIESF RKANGSYKPG RIIFYRDGVS EGQFSQVLLS EMDAIRKACA
     SIEEGYLPPV TFVVVQKRHH TRLFPEDHHA RDQMDRSRNI LPGTVVDTKI CHPSEFDFYL
     CSHSGIQGTS HPTHYYVLFD ENNFSADALQ TLTYHLCYTY ARCTRSVSIV PPVYYAHLAA
     SRARHYLEEG SLPDHGSSSA SAAGGSRRND RGVPVKPLPE IKENVKQFMF YC
 
 
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