ID   EPAB2_RAT               Reviewed;         269 AA.
AC   B0BNE4;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   26-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Embryonic polyadenylate-binding protein 2;
DE            Short=Embryonic poly(A)-binding protein 2;
DE            Short=ePABP-2;
DE            Short=ePABP2;
DE   AltName: Full=Embryonic poly(A)-binding protein type II;
DE   AltName: Full=Poly(A)-binding protein nuclear-like 1;
GN   Name=Pabpn1l; Synonyms=Epabp2, Pabpnl1;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Binds the poly(A) tail of mRNA. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
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DR   EMBL; BC158789; AAI58790.1; -; mRNA.
DR   RefSeq; NP_001107251.1; NM_001113779.1.
DR   AlphaFoldDB; B0BNE4; -.
DR   SMR; B0BNE4; -.
DR   STRING; 10116.ENSRNOP00000050572; -.
DR   jPOST; B0BNE4; -.
DR   PaxDb; B0BNE4; -.
DR   PeptideAtlas; B0BNE4; -.
DR   GeneID; 307920; -.
DR   KEGG; rno:307920; -.
DR   UCSC; RGD:1562761; rat.
DR   CTD; 390748; -.
DR   RGD; 1562761; Pabpn1l.
DR   VEuPathDB; HostDB:ENSRNOG00000029558; -.
DR   eggNOG; KOG4209; Eukaryota.
DR   HOGENOM; CLU_012062_23_2_1; -.
DR   InParanoid; B0BNE4; -.
DR   OMA; MWPFLSH; -.
DR   OrthoDB; 1412946at2759; -.
DR   PhylomeDB; B0BNE4; -.
DR   PRO; PR:B0BNE4; -.
DR   Proteomes; UP000002494; Chromosome 19.
DR   Bgee; ENSRNOG00000029558; Expressed in thymus and 4 other tissues.
DR   GO; GO:0005737; C:cytoplasm; ISO:RGD.
DR   GO; GO:0008143; F:poly(A) binding; ISO:RGD.
DR   GO; GO:0003723; F:RNA binding; ISO:RGD.
DR   GO; GO:0160021; P:maternal-to-zygotic transition of gene expression; ISO:RGD.
DR   GO; GO:0032091; P:negative regulation of protein binding; ISO:RGD.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; ISO:RGD.
DR   GO; GO:0062026; P:negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process; ISO:RGD.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; ISO:RGD.
DR   Gene3D; 3.30.70.330; -; 1.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   Pfam; PF00076; RRM_1; 1.
DR   SMART; SM00360; RRM; 1.
DR   SUPFAM; SSF54928; SSF54928; 1.
DR   PROSITE; PS50102; RRM; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Reference proteome; RNA-binding.
FT   CHAIN           1..269
FT                   /note="Embryonic polyadenylate-binding protein 2"
FT                   /id="PRO_0000349173"
FT   DOMAIN          139..216
FT                   /note="RRM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   REGION          26..54
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          240..269
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   269 AA;  29861 MW;  556B0E20F0952CF4 CRC64;
     MWPSLSNELF PPPTEVWLQT VSSDPEAQGW GAWGRTEKTS LVPSAGSDKE AEENEDSSFL
     LSLLEPENLA KSPVYNQELE AIRLKLWTME HAEVLPEPPS VQRKATEEER AEARELLSPE
     TIGCFFPGAP KENVEADHRS VYVGNVDYGG SAAELEAYFS PCGEIHRVTI LCDKFSGHPK
     GYAYIEFASK SSVQAAVRLD ESTFRGRVIK VLPKRTNFPG ISSTDRGGLR THSSSRAAFL
     QGSLQRKPRL RPHGQSRGRG RASPWFSPY