ID   AGO13_ORYSJ             Reviewed;        1192 AA.
AC   Q852N2; Q0DMW4; Q10CA6;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Protein argonaute 13;
DE            Short=OsAGO13;
GN   Name=AGO13; OrderedLocusNames=Os03g0789500, LOC_Os03g57560;
GN   ORFNames=OSJNBa0087O09.9;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16109971; DOI=10.1101/gr.3869505;
RG   The rice chromosome 3 sequencing consortium;
RA   Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA   Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA   Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA   Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA   Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA   Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA   Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA   Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA   Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA   Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA   O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA   Jin W., Lee H.R., Jiang J., Jackson S.;
RT   "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT   and diverged grass species.";
RL   Genome Res. 15:1284-1291(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 966-1192.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [6]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=18826656; DOI=10.1186/1471-2164-9-451;
RA   Kapoor M., Arora R., Lama T., Nijhawan A., Khurana J.P., Tyagi A.K.,
RA   Kapoor S.;
RT   "Genome-wide identification, organization and phylogenetic analysis of
RT   dicer-like, argonaute and RNA-dependent RNA polymerase gene families and
RT   their expression analysis during reproductive development and stress in
RT   rice.";
RL   BMC Genomics 9:451-451(2008).
CC   -!- FUNCTION: Probably involved in the RNA silencing pathway. May bind to
CC       short RNAs such as microRNAs (miRNAs) or short interfering RNAs
CC       (siRNAs), and represses the translation of mRNAs which are
CC       complementary to them (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the argonaute family. Ago subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABF99267.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=BAF13424.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AC087096; AAO24917.1; -; Genomic_DNA.
DR   EMBL; DP000009; ABF99267.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP008209; BAF13424.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014959; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AK059333; -; NOT_ANNOTATED_CDS; mRNA.
DR   AlphaFoldDB; Q852N2; -.
DR   SMR; Q852N2; -.
DR   PaxDb; Q852N2; -.
DR   PRIDE; Q852N2; -.
DR   InParanoid; Q852N2; -.
DR   Proteomes; UP000000763; Chromosome 3.
DR   Proteomes; UP000059680; Chromosome 3.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0004521; F:endoribonuclease activity; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0035194; P:post-transcriptional gene silencing by RNA; IBA:GO_Central.
DR   CDD; cd04657; Piwi_ago-like; 1.
DR   Gene3D; 3.30.420.10; -; 1.
DR   InterPro; IPR014811; ArgoL1.
DR   InterPro; IPR032472; ArgoL2.
DR   InterPro; IPR032473; Argonaute_Mid_dom.
DR   InterPro; IPR032474; Argonaute_N.
DR   InterPro; IPR003100; PAZ_dom.
DR   InterPro; IPR036085; PAZ_dom_sf.
DR   InterPro; IPR003165; Piwi.
DR   InterPro; IPR045246; Piwi_ago-like.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   Pfam; PF08699; ArgoL1; 1.
DR   Pfam; PF16488; ArgoL2; 1.
DR   Pfam; PF16487; ArgoMid; 1.
DR   Pfam; PF16486; ArgoN; 1.
DR   Pfam; PF02170; PAZ; 1.
DR   Pfam; PF02171; Piwi; 1.
DR   SMART; SM01163; DUF1785; 1.
DR   SMART; SM00949; PAZ; 1.
DR   SMART; SM00950; Piwi; 1.
DR   SUPFAM; SSF101690; SSF101690; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   SUPFAM; SSF54236; SSF54236; 1.
DR   PROSITE; PS50821; PAZ; 1.
DR   PROSITE; PS50822; PIWI; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; RNA-mediated gene silencing.
FT   CHAIN           1..1192
FT                   /note="Protein argonaute 13"
FT                   /id="PRO_0000378436"
FT   DOMAIN          182..296
FT                   /note="PAZ"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00142"
FT   DOMAIN          472..770
FT                   /note="Piwi"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00150"
SQ   SEQUENCE   1192 AA;  135727 MW;  955D521B941EA74E CRC64;
     MPLKFCMERG FQSHPVRGCL VGASRFLSCI KFLVSINPES KSRATNREVL NELIKLHGKT
     SLGGKLPAYD GRKSLYTAGS LPFESEEFVV KLIDPEKKDK ERAEREYKIT IRIAGRTDFY
     HLQQFLLGRQ RDMPQETIQF GHRGDIGEGL ECWRGYYQSL RPTQMGLSLN IDISATSFFK
     PVTVIQFVEE FLNIRDTSRP LSDRDRVKIK KALRGVRIET NHQEDQIRRY KITGITPIPM
     SQLIFPVDDN GTRKTVVQYF WDRYNYRLKY ASWPCLQSGS DSRPVYLPME VCKIVEGQRY
     SKKLNNKQVT NILRATCQRP QQREQRIHEM VLHNKYTDDR FAQEFGIKVC NDLVSVPARV
     LPPPMLKYHD SGREKTCAPS VGQWNMINKK MINGGTVDNW TCLSFSRMRP EEVQRFCGDL
     IQMCNATGMS FNPRPVVDVR SSNPNNIENA LRDVHSRTSE LLAREGKGGL QLLIVILLEV
     SGSYGKIKRV CENDLGIVSQ CCLPRHASRP NKQYLENVAL KINVKKSQQS SLVLMSHTPP
     GEDSASSIAA VVASMDWPEI TKYRGLVSAQ SHRQEIIEDL FSVGKDPVKV VNGGMIREFL
     IAFRKKTGRR PERIIFYRDG VSEGQFSRVL LHEMDAIRKA CASLEEGYLP PVTFVVVQKR
     HHTRLFPEVH GRRDMTDKSG NILPGTVKDR QICHPTEFYF YLCSHAGIQG TSRPTHYHVL
     YDENHFTADE LQTLTNNLCY IYARCTHAVS VVPPAYYSHL AASHAHCCIK GHSSGSGSTP
     GNEHDIVKNS APTLQILVKV LDFQIVPLTM KLKSSAEDIV ALALSKHRVS LHDVYVYHGR
     RVIAKSLTLE SLKADRDSTF LIMPRMRGGC NDTIGGFKCI PLEQHIRSLG DSLFEIIWIP
     PDLRVSGFCS YLIILGKPAR KIICQLLKLL EIIHAANRFA SRFTIADLVF LPDLGCIAFK
     KGVKIRWNLR REEYKLNMGD VASIISCWFR FNRRKLEALE AGIHELRPGQ GDSPMFVDIL
     VKDLRSPTHE TGLSANYRGF YKNCSALRSC SAHMNLFTSL DIRKDFMVGS ADWGNFVKAL
     GDIKLPGWYR TAMRSPEMRK VLFFEFNDPH TGELRGKRYR ALSVFSWLEF ARIFIKHMKK
     GLCTDKQATA LLCVIFSNIV PVVEKKLTYS YRPPAKEKSN ESFTVEEILD PS