AGO14_ORYSJ
ID AGO14_ORYSJ Reviewed; 1052 AA.
AC Q6Z4F1; A0A0P0X377;
DT 07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 95.
DE RecName: Full=Protein argonaute 14;
DE Short=OsAGO14;
GN Name=AGO14; OrderedLocusNames=Os07g0188000, LOC_Os07g09020;
GN ORFNames=OSJNBb0002L09.2, OSJNBb0084L07.14;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [5]
RP TISSUE SPECIFICITY, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18826656; DOI=10.1186/1471-2164-9-451;
RA Kapoor M., Arora R., Lama T., Nijhawan A., Khurana J.P., Tyagi A.K.,
RA Kapoor S.;
RT "Genome-wide identification, organization and phylogenetic analysis of
RT dicer-like, argonaute and RNA-dependent RNA polymerase gene families and
RT their expression analysis during reproductive development and stress in
RT rice.";
RL BMC Genomics 9:451-451(2008).
CC -!- FUNCTION: Probably involved in the RNA silencing pathway. May bind to
CC short RNAs such as microRNAs (miRNAs) or short interfering RNAs
CC (siRNAs), and represses the translation of mRNAs which are
CC complementary to them (By similarity). {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in seeds. {ECO:0000269|PubMed:18826656}.
CC -!- SIMILARITY: Belongs to the argonaute family. Ago subfamily.
CC {ECO:0000305}.
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DR EMBL; AP005179; BAC83909.1; -; Genomic_DNA.
DR EMBL; AP005877; BAD31843.1; -; Genomic_DNA.
DR EMBL; AP008213; BAF20993.1; -; Genomic_DNA.
DR EMBL; AP014963; BAT00388.1; -; Genomic_DNA.
DR EMBL; AK100285; BAG94531.1; -; mRNA.
DR RefSeq; XP_015645442.1; XM_015789956.1.
DR AlphaFoldDB; Q6Z4F1; -.
DR SMR; Q6Z4F1; -.
DR STRING; 4530.OS07T0188000-01; -.
DR PaxDb; Q6Z4F1; -.
DR PRIDE; Q6Z4F1; -.
DR EnsemblPlants; Os07t0188000-01; Os07t0188000-01; Os07g0188000.
DR GeneID; 4342603; -.
DR Gramene; Os07t0188000-01; Os07t0188000-01; Os07g0188000.
DR KEGG; osa:4342603; -.
DR eggNOG; KOG1041; Eukaryota.
DR HOGENOM; CLU_004544_0_0_1; -.
DR InParanoid; Q6Z4F1; -.
DR OMA; FSRMHID; -.
DR OrthoDB; 159407at2759; -.
DR Proteomes; UP000000763; Chromosome 7.
DR Proteomes; UP000059680; Chromosome 7.
DR Genevisible; Q6Z4F1; OS.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0004521; F:endoribonuclease activity; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0035194; P:post-transcriptional gene silencing by RNA; IBA:GO_Central.
DR CDD; cd04657; Piwi_ago-like; 1.
DR Gene3D; 3.30.420.10; -; 1.
DR InterPro; IPR014811; ArgoL1.
DR InterPro; IPR032472; ArgoL2.
DR InterPro; IPR032473; Argonaute_Mid_dom.
DR InterPro; IPR032474; Argonaute_N.
DR InterPro; IPR003100; PAZ_dom.
DR InterPro; IPR036085; PAZ_dom_sf.
DR InterPro; IPR003165; Piwi.
DR InterPro; IPR045246; Piwi_ago-like.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR Pfam; PF08699; ArgoL1; 1.
DR Pfam; PF16488; ArgoL2; 1.
DR Pfam; PF16487; ArgoMid; 1.
DR Pfam; PF16486; ArgoN; 1.
DR Pfam; PF02170; PAZ; 1.
DR Pfam; PF02171; Piwi; 1.
DR SMART; SM01163; DUF1785; 1.
DR SMART; SM00949; PAZ; 1.
DR SMART; SM00950; Piwi; 1.
DR SUPFAM; SSF101690; SSF101690; 1.
DR SUPFAM; SSF53098; SSF53098; 1.
DR PROSITE; PS50821; PAZ; 1.
DR PROSITE; PS50822; PIWI; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; RNA-mediated gene silencing.
FT CHAIN 1..1052
FT /note="Protein argonaute 14"
FT /id="PRO_0000378437"
FT DOMAIN 393..510
FT /note="PAZ"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00142"
FT DOMAIN 677..1009
FT /note="Piwi"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00150"
FT REGION 1..127
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 170..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 173..189
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1052 AA; 113910 MW; 0B9BB5FE57E8738D CRC64;
MASRGGDGLV GGGRGPLGGR DGRGRGPAGG RGGGRGGGHP QQQQQQQPGY GRGDGGGRGP
APAAGGVVGR GTGGGGGGGR GDGGRGRGRG GGGGDGVRPA MAAAPAASTP GPVAVAARST
PPPTPAVQIP AVASSSSAQP AAAAQPPPAA AAVSALARDV GRQLAVVAGG GRPAPPAAPP
APIPVSSKGV APPSRPGFGT VGERIVVRAN HFLVRVSDND MIYLYDVSLS PPPKTRRINR
VVMSELARLH RESHLGGISF AYDGSKALYT AGKLPFDSMD FKIKLGKELR EIEYKVTIRR
AGQADLHHLH EFIAGRQRDS QQQTIQALDV VLRESPSLNY VIVSRSFYST MFGRQDIGDG
LECWKGYYQS LRPTQMGLSL NIDISSTPFF KPISVVEYVK NCLGTPTNAN GPDPRRPLSD
IDRLKVKKAL RGVRVETTHQ GKSSKYKITT ITSEPLSQLN FSMDGTTQTV IQYFSQRYKY
RLQYTSWPCL QSGNPSNPIY LPMEVCTIVE GQRYSKKLND KQVTGLLRAT CQPPQKREQK
IIEMVQHNNY PADKVVSDFR INISNQMATM PARVLPAPTL RYHDSGKEKT CNPRVGQWNM
INKKMVGGAV VQKWTCVNFS RMHIDAVHRL CGELVYTCNA IGMVFNEMPE IEVGSAAPNN
IEAALSNIHT RAPQLQLLIV ILPDVNGYYG RIKRVCETEL GIVSQCLKPG RKLLSLDRQF
LENVSLKINV KAGGRNSVLQ RPLVPGGLEN TTIIFGADVT HPASGEDSSA SIAAVVASMD
WPEITKYKAL VSAQPPRQEI IQDLFTMTEV AQNADAPAQK AEGSKKNFIC GGMFRELLMS
FYSKNAKRKP QRIIFYRDGV SDGQFLHVLL YEMDAIKKAI ASLDPAYRPL VTFVVVQKRH
HTRLFPEVHG RQDLTDRSGN VRPGTVVDTN ICHPSEFDFY LCSHAGIQGT SRPTHYHVLH
DENRFSADQL QMLTYNLCYT YARCTRSVSV VPPAYYAHLA AFRARYYDEP PAMDGASSVG
SGGNQAAAGG QPPAVRRLPQ IKENVKDVMF YC
