ID   AGO17_ORYSJ             Reviewed;         876 AA.
AC   Q6H6C3; A0A0P0VFD0;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Protein argonaute 17;
DE            Short=OsAGO17;
GN   Name=AGO17; OrderedLocusNames=Os02g0169400, LOC_Os02g07310;
GN   ORFNames=OJ1116_A06.3, OsJ_05545, P0669G09.26;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [6]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=18826656; DOI=10.1186/1471-2164-9-451;
RA   Kapoor M., Arora R., Lama T., Nijhawan A., Khurana J.P., Tyagi A.K.,
RA   Kapoor S.;
RT   "Genome-wide identification, organization and phylogenetic analysis of
RT   dicer-like, argonaute and RNA-dependent RNA polymerase gene families and
RT   their expression analysis during reproductive development and stress in
RT   rice.";
RL   BMC Genomics 9:451-451(2008).
CC   -!- FUNCTION: Probably involved in the RNA silencing pathway. May bind to
CC       short RNAs such as microRNAs (miRNAs) or short interfering RNAs
CC       (siRNAs), and represses the translation of mRNAs which are
CC       complementary to them (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the argonaute family. Ago subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AP004113; BAD25174.1; -; Genomic_DNA.
DR   EMBL; AP005071; BAD25726.1; -; Genomic_DNA.
DR   EMBL; AP008208; BAF07935.1; -; Genomic_DNA.
DR   EMBL; AP014958; BAS77186.1; -; Genomic_DNA.
DR   EMBL; CM000139; EEE56394.1; -; Genomic_DNA.
DR   EMBL; AK106247; BAG97655.1; -; mRNA.
DR   RefSeq; XP_015624008.1; XM_015768522.1.
DR   AlphaFoldDB; Q6H6C3; -.
DR   SMR; Q6H6C3; -.
DR   STRING; 4530.OS02T0169400-01; -.
DR   PaxDb; Q6H6C3; -.
DR   PRIDE; Q6H6C3; -.
DR   EnsemblPlants; Os02t0169400-01; Os02t0169400-01; Os02g0169400.
DR   GeneID; 4328436; -.
DR   Gramene; Os02t0169400-01; Os02t0169400-01; Os02g0169400.
DR   KEGG; osa:4328436; -.
DR   eggNOG; KOG1041; Eukaryota.
DR   HOGENOM; CLU_004544_0_1_1; -.
DR   InParanoid; Q6H6C3; -.
DR   OMA; FYQNVVE; -.
DR   OrthoDB; 159407at2759; -.
DR   Proteomes; UP000000763; Chromosome 2.
DR   Proteomes; UP000007752; Chromosome 2.
DR   Proteomes; UP000059680; Chromosome 2.
DR   Genevisible; Q6H6C3; OS.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0004521; F:endoribonuclease activity; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0035194; P:post-transcriptional gene silencing by RNA; IBA:GO_Central.
DR   CDD; cd04657; Piwi_ago-like; 1.
DR   Gene3D; 3.30.420.10; -; 1.
DR   InterPro; IPR014811; ArgoL1.
DR   InterPro; IPR032472; ArgoL2.
DR   InterPro; IPR032473; Argonaute_Mid_dom.
DR   InterPro; IPR032474; Argonaute_N.
DR   InterPro; IPR003100; PAZ_dom.
DR   InterPro; IPR036085; PAZ_dom_sf.
DR   InterPro; IPR003165; Piwi.
DR   InterPro; IPR045246; Piwi_ago-like.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   Pfam; PF08699; ArgoL1; 1.
DR   Pfam; PF16488; ArgoL2; 1.
DR   Pfam; PF16487; ArgoMid; 1.
DR   Pfam; PF16486; ArgoN; 1.
DR   Pfam; PF02171; Piwi; 1.
DR   SMART; SM01163; DUF1785; 1.
DR   SMART; SM00950; Piwi; 1.
DR   SUPFAM; SSF101690; SSF101690; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   PROSITE; PS50821; PAZ; 1.
DR   PROSITE; PS50822; PIWI; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; RNA-mediated gene silencing.
FT   CHAIN           1..876
FT                   /note="Protein argonaute 17"
FT                   /id="PRO_0000378440"
FT   DOMAIN          228..338
FT                   /note="PAZ"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00142"
FT   DOMAIN          514..834
FT                   /note="Piwi"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00150"
FT   REGION          839..859
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   876 AA;  98912 MW;  3E89DCB98203E709 CRC64;
     MESQRMTWLY DRHHSLKHNK AERQAILSTY RLAKRPNLSS EGMIGESCIV RTNCFSVHLE
     SLDDQTIYEY DVCVTPEVGI NRAVIRELVK QQKDSGLGGR LPAYDGRKRL YTSGPLPFDS
     HRFLVLLDSI EDSPEESRHL RVRDFVVTLK FAAKISLWTL RKFRGGKPNR ESRAALRALD
     VVLKELPTAR YTQFAGSFYS PNLGECRQLC KVLESWRGFH QRIQATQMGL QLNIDVSSSV
     FIKPVPVVDY VAQLLNEDIL LDRPLCSTEF LKIKEALEGL KVQINGILFN TYHVQDLVHQ
     AASFPVNFSI QYPSLPCLKV AHFGETIFLP LEVCKIAEGQ CHQKQLNAKH MAALLQVARQ
     PPNERDYNIL QTVHQNKYQE DPHAKEFGIK IEEKLVSIKS RILPAPWLKF HDSGETTEFL
     PQLGIWNMMH KKMINGGRVK SWACVNFCWS VREYAARNFC YDLGFMCRES GMVFSVKPVL
     PLVIAKPGCV ESALRTLHDD VMDILRPQGR KLDLLIVILP NNNGSLYGDV KRICETDIGL
     ISQCCLAKHV LKMNKWYLAS VALKINAKMG GRNTVLVDAL EMRLPHVRDT PTIVFGAHVT
     HPHPGKANSS SIAAVVASQD WPEVTKYAGL ISVQACHQES IQGLFKVQDD PERGTTTSGM
     IKEHLMSFYR ATKRKPGRII FYRDGVSKGQ LPQALMHELG AIKMACASMG PDYNPLVTYV
     VLQKCRHTRL FADYYNANTH DSTANIRAGT VVDSNICQPN QFDFYLCSHR STQGTKRPRY
     YHVLWDENDF LAGSFQELTN YLCYTSATCT QSISVVAPVH YARLLSSRAR CYIKPRSIGD
     STSHTSLPSE EDSSAASETG SLLPIKDNLK GAMFFC