EPFL7_ARATH
ID EPFL7_ARATH Reviewed; 172 AA.
AC C4B8C5;
DT 23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT 07-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 52.
DE RecName: Full=EPIDERMAL PATTERNING FACTOR-like protein 7 {ECO:0000303|PubMed:19435754};
DE Short=EPF-like protein 7;
DE Contains:
DE RecName: Full=MEPFL7 {ECO:0000305};
DE Flags: Precursor;
GN Name=EPFL7 {ECO:0000303|PubMed:19435754};
GN OrderedLocusNames=At1g71866 {ECO:0000312|Araport:AT1G71866};
GN ORFNames=F14O23, F17M19;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19435754; DOI=10.1093/pcp/pcp068;
RA Hara K., Yokoo T., Kajita R., Onishi T., Yahata S., Peterson K.M.,
RA Torii K.U., Kakimoto T.;
RT "Epidermal cell density is autoregulated via a secretory peptide, EPIDERMAL
RT PATTERNING FACTOR 2 in Arabidopsis leaves.";
RL Plant Cell Physiol. 50:1019-1031(2009).
RN [4]
RP 3D-STRUCTURE MODELING, AND DISULFIDE BOND.
RX PubMed=22027592; DOI=10.1038/ncomms1520;
RA Ohki S., Takeuchi M., Mori M.;
RT "The NMR structure of stomagen reveals the basis of stomatal density
RT regulation by plant peptide hormones.";
RL Nat. Commun. 2:512-512(2011).
CC -!- FUNCTION: Controls stomatal patterning. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the plant cysteine rich small secretory peptide
CC family. Epidermal patterning factor subfamily. {ECO:0000305}.
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DR EMBL; AC012654; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC021665; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002684; AEE35245.1; -; Genomic_DNA.
DR EMBL; AB499313; BAH58783.1; -; mRNA.
DR RefSeq; NP_001185375.1; NM_001198446.1.
DR AlphaFoldDB; C4B8C5; -.
DR SMR; C4B8C5; -.
DR STRING; 3702.AT1G71866.1; -.
DR PaxDb; C4B8C5; -.
DR EnsemblPlants; AT1G71866.1; AT1G71866.1; AT1G71866.
DR GeneID; 10723086; -.
DR Gramene; AT1G71866.1; AT1G71866.1; AT1G71866.
DR KEGG; ath:AT1G71866; -.
DR Araport; AT1G71866; -.
DR TAIR; locus:6530298168; AT1G71866.
DR HOGENOM; CLU_1557393_0_0_1; -.
DR OrthoDB; 1592853at2759; -.
DR PRO; PR:C4B8C5; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; C4B8C5; baseline and differential.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0010052; P:guard cell differentiation; ISS:UniProtKB.
DR GO; GO:0010374; P:stomatal complex development; ISS:UniProtKB.
DR InterPro; IPR039455; EPFL.
DR PANTHER; PTHR33109; PTHR33109; 1.
PE 1: Evidence at protein level;
KW Developmental protein; Disulfide bond; Reference proteome; Secreted;
KW Signal.
FT SIGNAL 1..27
FT /evidence="ECO:0000255"
FT CHAIN 28..172
FT /note="EPIDERMAL PATTERNING FACTOR-like protein 7"
FT /id="PRO_0000392505"
FT CHAIN 121..172
FT /note="MEPFL7"
FT /evidence="ECO:0000303|PubMed:22027592"
FT /id="PRO_0000430513"
FT DISULFID 128..159
FT /evidence="ECO:0000303|PubMed:22027592"
FT DISULFID 132..138
FT /evidence="ECO:0000303|PubMed:22027592"
FT DISULFID 135..161
FT /evidence="ECO:0000303|PubMed:22027592"
FT DISULFID 147..153
FT /evidence="ECO:0000269|PubMed:22027592"
SQ SEQUENCE 172 AA; 19322 MW; 02B6A16788EC7281 CRC64;
MDHVNPTLFH LKSLSIFTLT LLYISSPHFL LFKTLSMYEN LRIFLKIIPF NLFGMKSVSL
IAILLLHLFV SSDTFQLDLF HCKYYLAITW LINRDNECVI YILVGSFICC IVICEVVDKA
SGSSIPDCSN ACGPCKPCKL VVISSTCSAS EACPLVYKCL CKGKYYHVPS LT
