ID   AGO1B_ORYSJ             Reviewed;        1118 AA.
AC   Q7XSA2; Q0JAZ2;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   07-JUL-2009, sequence version 3.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Protein argonaute 1B;
DE            Short=OsAGO1b;
GN   Name=AGO1B; OrderedLocusNames=Os04g0566500, LOC_Os04g47870;
GN   ORFNames=OSJNBa0005N02.3;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12447439; DOI=10.1038/nature01183;
RA   Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA   Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA   Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA   Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA   Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA   Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA   Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA   Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA   Li J., Hong G., Xue Y., Han B.;
RT   "Sequence and analysis of rice chromosome 4.";
RL   Nature 420:316-320(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [6]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=18826656; DOI=10.1186/1471-2164-9-451;
RA   Kapoor M., Arora R., Lama T., Nijhawan A., Khurana J.P., Tyagi A.K.,
RA   Kapoor S.;
RT   "Genome-wide identification, organization and phylogenetic analysis of
RT   dicer-like, argonaute and RNA-dependent RNA polymerase gene families and
RT   their expression analysis during reproductive development and stress in
RT   rice.";
RL   BMC Genomics 9:451-451(2008).
CC   -!- FUNCTION: Probably involved in the RNA silencing pathway. May bind to
CC       short RNAs such as microRNAs (miRNAs) or short interfering RNAs
CC       (siRNAs), and represses the translation of mRNAs which are
CC       complementary to them (By similarity). {ECO:0000250}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q7XSA2-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q7XSA2-2; Sequence=VSP_037581;
CC   -!- SIMILARITY: Belongs to the argonaute family. Ago subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAF15495.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AL662954; CAE02070.2; -; Genomic_DNA.
DR   EMBL; AP008210; BAF15495.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014960; BAS90531.1; -; Genomic_DNA.
DR   EMBL; AK111587; BAG99319.1; -; mRNA.
DR   RefSeq; XP_015636291.1; XM_015780805.1. [Q7XSA2-1]
DR   RefSeq; XP_015636292.1; XM_015780806.1. [Q7XSA2-2]
DR   AlphaFoldDB; Q7XSA2; -.
DR   SMR; Q7XSA2; -.
DR   STRING; 4530.OS04T0566500-04; -.
DR   PaxDb; Q7XSA2; -.
DR   PRIDE; Q7XSA2; -.
DR   EnsemblPlants; Os04t0566500-03; Os04t0566500-03; Os04g0566500. [Q7XSA2-2]
DR   EnsemblPlants; Os04t0566500-04; Os04t0566500-04; Os04g0566500. [Q7XSA2-2]
DR   GeneID; 9270411; -.
DR   Gramene; Os04t0566500-03; Os04t0566500-03; Os04g0566500. [Q7XSA2-2]
DR   Gramene; Os04t0566500-04; Os04t0566500-04; Os04g0566500. [Q7XSA2-2]
DR   KEGG; osa:9270411; -.
DR   eggNOG; KOG1041; Eukaryota.
DR   HOGENOM; CLU_004544_0_0_1; -.
DR   InParanoid; Q7XSA2; -.
DR   OMA; VGANRHY; -.
DR   OrthoDB; 159407at2759; -.
DR   Proteomes; UP000000763; Chromosome 4.
DR   Proteomes; UP000059680; Chromosome 4.
DR   Genevisible; Q7XSA2; OS.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0004521; F:endoribonuclease activity; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0035194; P:post-transcriptional gene silencing by RNA; IBA:GO_Central.
DR   CDD; cd04657; Piwi_ago-like; 1.
DR   Gene3D; 3.30.420.10; -; 1.
DR   InterPro; IPR014811; ArgoL1.
DR   InterPro; IPR032472; ArgoL2.
DR   InterPro; IPR024357; Argonaut_Gly-rich.
DR   InterPro; IPR032473; Argonaute_Mid_dom.
DR   InterPro; IPR032474; Argonaute_N.
DR   InterPro; IPR003100; PAZ_dom.
DR   InterPro; IPR036085; PAZ_dom_sf.
DR   InterPro; IPR003165; Piwi.
DR   InterPro; IPR045246; Piwi_ago-like.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   Pfam; PF08699; ArgoL1; 1.
DR   Pfam; PF16488; ArgoL2; 1.
DR   Pfam; PF16487; ArgoMid; 1.
DR   Pfam; PF16486; ArgoN; 1.
DR   Pfam; PF12764; Gly-rich_Ago1; 1.
DR   Pfam; PF02170; PAZ; 1.
DR   Pfam; PF02171; Piwi; 1.
DR   SMART; SM01163; DUF1785; 1.
DR   SMART; SM00949; PAZ; 1.
DR   SMART; SM00950; Piwi; 1.
DR   SUPFAM; SSF101690; SSF101690; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   PROSITE; PS50821; PAZ; 1.
DR   PROSITE; PS50822; PIWI; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Reference proteome; RNA-mediated gene silencing.
FT   CHAIN           1..1118
FT                   /note="Protein argonaute 1B"
FT                   /id="PRO_0000378426"
FT   DOMAIN          456..570
FT                   /note="PAZ"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00142"
FT   DOMAIN          746..1067
FT                   /note="Piwi"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00150"
FT   REGION          1..175
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          188..246
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        188..237
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         1..17
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:12869764"
FT                   /id="VSP_037581"
SQ   SEQUENCE   1118 AA;  123592 MW;  62DB0177EB54464F CRC64;
     MALQLENGRP HHHQVPIMVK KKRTGSGSTG ESSGEAPGAP GHGSSQRAER GPQQHGGGRG
     WVPQHGGRGG GQYQGRGGHY QGRGGQGSHH PGGGPPEYQG RGGPGSHHPG GGPPDYQGRG
     GSGSHHPGGG PPEYQPRDYQ GRGGPRPRGG MPQPYYGGPR GSGGRSVPSG SSRTVPELHQ
     APHVQYQAPM VSPTPSGAGS SSQPAAEVSS GQVQQQFQQL ATRDQSSTSQ AIQIAPPSSK
     SVRFPLRPGK GTYGDRCIVK ANHFFAELPD KDLHQYDVSI TPEVTSRGVN RAVMFELVTL
     YRYSHLGGRL PAYDGRKSLY TAGPLPFASR TFEITLQDEE DSLGGGQGTQ RRERLFRVVI
     KFAARADLHH LAMFLAGRQA DAPQEALQVL DIVLRELPTT RYSPVGRSFY SPNLGRRQQL
     GEGLESWRGF YQSIRPTQMG LSLNIDMSST AFIEPLPVID FVAQLLNRDI SVRPLSDSDR
     VKIKKALRGV KVEVTHRGNM RRKYRISGLT SQATRELSFP VDDRGTVKTV VQYFLETYGF
     SIQHTTLPCL QVGNQQRPNY LPMEVCKIVE GQRYSKRLNE KQITALLKVT CQRPQERELD
     ILRTVSHNAY HEDQYAQEFG IKIDERLASV EARVLPPPRL KYHDSGREKD VLPRVGQWNM
     MNKKMVNGGR VNNWACINFS RNVQDSAARG FCHELAIMCQ ISGMDFALEP VLPPLTARPE
     HVERALKARY QDAMNMLRPQ GRELDLLIVI LPDNNGSLYG DLKRICETDL GLVSQCCLTK
     HVFKMSKQYL ANVALKINVK VGGRNTVLVD ALTRRIPLVS DRPTIIFGAD VTHPHPGEDS
     SPSIAAVVAS QDWPEVTKYA GLVSAQAHRQ ELIQDLFKVW QDPHRGTVTG GMIKELLISF
     KRATGQKPQR IIFYRDGVSE GQFYQVLLYE LDAIRKACAS LEPNYQPPVT FVVVQKRHHT
     RLFANNHNDQ RTVDRSGNIL PGTVVDSKIC HPTEFDFYLC SHAGIQGTSR PAHYHVLWDE
     NKFTADELQT LTNNLCYTYA RCTRSVSIVP PAYYAHLAAF RARFYMEPET SDSGSMASGA
     ATSRGLPPGV RSARVAGNVA VRPLPALKEN VKRVMFYC