AGO1C_ORYSJ
ID AGO1C_ORYSJ Reviewed; 1011 AA.
AC Q6K972; A0A0P0VRQ6; Q8LNZ9;
DT 07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=Protein argonaute 1C;
DE Short=OsAGO1c;
DE AltName: Full=Protein argonaute 1;
DE Short=OsAGO1;
GN Name=AGO1C; Synonyms=AGO1; OrderedLocusNames=Os02g0831600, LOC_Os02g58490;
GN ORFNames=OJ1149_C12.13, OsJ_08998;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Taichung 65; TISSUE=Embryo;
RX PubMed=12000455; DOI=10.1046/j.1365-313x.2002.01279.x;
RA Nishimura A., Ito M., Kamiya N., Sato Y., Matsuoka M.;
RT "OsPNH1 regulates leaf development and maintenance of the shoot apical
RT meristem in rice.";
RL Plant J. 30:189-201(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18826656; DOI=10.1186/1471-2164-9-451;
RA Kapoor M., Arora R., Lama T., Nijhawan A., Khurana J.P., Tyagi A.K.,
RA Kapoor S.;
RT "Genome-wide identification, organization and phylogenetic analysis of
RT dicer-like, argonaute and RNA-dependent RNA polymerase gene families and
RT their expression analysis during reproductive development and stress in
RT rice.";
RL BMC Genomics 9:451-451(2008).
CC -!- FUNCTION: Probably involved in the RNA silencing pathway. May bind to
CC short RNAs such as microRNAs (miRNAs) or short interfering RNAs
CC (siRNAs), and represses the translation of mRNAs which are
CC complementary to them (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the argonaute family. Ago subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB96814.1; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305};
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DR EMBL; AB081951; BAB96814.1; ALT_SEQ; mRNA.
DR EMBL; AP004082; BAD23006.1; -; Genomic_DNA.
DR EMBL; AP008208; BAF10535.1; -; Genomic_DNA.
DR EMBL; AP014958; BAS81760.1; -; Genomic_DNA.
DR EMBL; CM000139; EEE58113.1; -; Genomic_DNA.
DR EMBL; AK103279; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015626468.1; XM_015770982.1.
DR RefSeq; XP_015626469.1; XM_015770983.1.
DR AlphaFoldDB; Q6K972; -.
DR SMR; Q6K972; -.
DR STRING; 4530.OS02T0831600-01; -.
DR iPTMnet; Q6K972; -.
DR PaxDb; Q6K972; -.
DR PRIDE; Q6K972; -.
DR EnsemblPlants; Os02t0831600-01; Os02t0831600-01; Os02g0831600.
DR GeneID; 4331253; -.
DR Gramene; Os02t0831600-01; Os02t0831600-01; Os02g0831600.
DR KEGG; osa:4331253; -.
DR eggNOG; KOG1041; Eukaryota.
DR HOGENOM; CLU_004544_0_0_1; -.
DR InParanoid; Q6K972; -.
DR OMA; DLYKIWQ; -.
DR OrthoDB; 159407at2759; -.
DR Proteomes; UP000000763; Chromosome 2.
DR Proteomes; UP000007752; Chromosome 2.
DR Proteomes; UP000059680; Chromosome 2.
DR Genevisible; Q6K972; OS.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0004521; F:endoribonuclease activity; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0035194; P:post-transcriptional gene silencing by RNA; IBA:GO_Central.
DR CDD; cd04657; Piwi_ago-like; 1.
DR Gene3D; 3.30.420.10; -; 1.
DR InterPro; IPR014811; ArgoL1.
DR InterPro; IPR032472; ArgoL2.
DR InterPro; IPR032473; Argonaute_Mid_dom.
DR InterPro; IPR032474; Argonaute_N.
DR InterPro; IPR003100; PAZ_dom.
DR InterPro; IPR036085; PAZ_dom_sf.
DR InterPro; IPR003165; Piwi.
DR InterPro; IPR045246; Piwi_ago-like.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR Pfam; PF08699; ArgoL1; 1.
DR Pfam; PF16488; ArgoL2; 1.
DR Pfam; PF16487; ArgoMid; 1.
DR Pfam; PF16486; ArgoN; 1.
DR Pfam; PF02170; PAZ; 1.
DR Pfam; PF02171; Piwi; 1.
DR SMART; SM01163; DUF1785; 1.
DR SMART; SM00949; PAZ; 1.
DR SMART; SM00950; Piwi; 1.
DR SUPFAM; SSF101690; SSF101690; 1.
DR SUPFAM; SSF53098; SSF53098; 1.
DR PROSITE; PS50821; PAZ; 1.
DR PROSITE; PS50822; PIWI; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; RNA-mediated gene silencing.
FT CHAIN 1..1011
FT /note="Protein argonaute 1C"
FT /id="PRO_0000378427"
FT DOMAIN 351..462
FT /note="PAZ"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00142"
FT DOMAIN 638..959
FT /note="Piwi"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00150"
FT REGION 1..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 107..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 963..994
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..48
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..95
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 122..137
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 963..988
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 307
FT /note="P -> A (in Ref. 6; AK103279)"
FT /evidence="ECO:0000305"
FT CONFLICT 882
FT /note="C -> R (in Ref. 6; AK103279)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 1011 AA; 113144 MW; 5614CA36BC7272EB CRC64;
MASRRPTHRH HTEAPDPGGR GRGRGRAARY AQPQPQPQQQ QQQQGRGCRA RGASPPPPPQ
QQQQQQPRST PTRATTVTVA SSSSTTATAS SSPLAPELRQ AIMEAPRPSE LAQPSPTPPQ
EQPVDAATTT PHHIPSSSKS IRFPLRPGKG TIGTRCMVKA NHFFAHLPNK DLHHYDVSIT
PEVTSRIVNR AVIKELVNLY KASYLGGRLP AYDGRKSLYT AGPLPFTSQE FQITLLDDDD
GSGSERRQRT FRVVIKFAAR ADLHRLELFL AGRHAEAPQE ALQVLDIVLR ELPSARYAPF
GRSFFSPYLG RRQPLGEGLE SWRGFYQSIR PTQMGLSLNI DMSATAFIEP LPVIDFVAQL
LNSDIHSRPL SDAERVKIKK ALRGVKVEVT HRGNMRRKYR ISGLTIQPTR ELTFPVDEGG
TVKSVVQYFQ ETYGFAIQHT YLPCLTVQRL NYLPMEVCKI VEGQRYSKRL NQNQIRALLE
ETCQHPRDRE RDIIKMVKHN AYQDDPYAKE FGIKISDRLA SVEARILPAP RLKYNETGRE
KDCLPRVGQW NMMNKKMVNG GKVRSWMCVN FARNVQESVV RGFCHELALM CQASGMDFAP
EPILPPLNAH PDQVERALKA RYHDAMNVLG PQRRELDLLI GILPDNNGSL YGDLKRVCEI
DLGIVSQCCC TKQVFKMNKQ ILANLALKIN VKVGGRNTVL VDAVSRRIPL VTDRPTIIFG
ADVTHPHPGE DSSPSIAAVV ASQDWPEVTK YAGLVSAQAH RQELIEDLYK IWQDPQRGTV
SGGMIRELLI SFKRSTGEKP QRIIFYRDGV SEGQFYQVLL YELNAIRKAC ASLETNYQPK
VTFIVVQKRH HTRLFAHNHN DQNSVDRSGN ILPGTVVDSK ICHPTEFDFY LCSHAGIKGT
SRPAHYHVLW DENNFTADAL QILTNNLCYT YARCTRSVSI VPPAYYAHLA AFRARFYMEP
DTSDSSSVVS GPGVRGPLSG SSTSRTRAPG GAAVKPLPAL KDSVKRVMFY C
