ID   EPS10_STRTR             Reviewed;         333 AA.
AC   Q8GP72;
DT   16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 20.
DE   RecName: Full=Capsular polysaccharide phosphotransferase eps10H;
DE            EC=2.7.-.-;
DE   AltName: Full=Stealth protein eps10H;
GN   Name=eps10H;
OS   Streptococcus thermophilus.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Rallu F., Ehrlich D.S., Renault P.;
RT   "Diversity of eps operons in Streptococcus thermophilus.";
RL   Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   IDENTIFICATION AS A STEALTH PROTEIN, AND PREDICTION OF FUNCTION.
RX   PubMed=16299590; DOI=10.1371/journal.pcbi.0010063;
RA   Sperisen P., Schmid C.D., Bucher P., Zilian O.;
RT   "Stealth proteins: in silico identification of a novel protein family
RT   rendering bacterial pathogens invisible to host immune defense.";
RL   PLoS Comput. Biol. 1:492-499(2005).
CC   -!- MISCELLANEOUS: Stealth proteins are part of a protein family that is
CC       conserved from bacteria to higher eukaryotes. Family members were first
CC       identified in microbes as proteins that help pathogens to elude the
CC       host innate immune system. Microbial stealth proteins are involved in
CC       the biosynthesis of exopolysaccharides. Stealth proteins are predicted
CC       to function as hexose-1-phosphoryltransferases.
CC   -!- SIMILARITY: Belongs to the stealth family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF454500; AAN63768.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8GP72; -.
DR   GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
DR   GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR031358; Stealth_CR1.
DR   InterPro; IPR021520; Stealth_CR2.
DR   InterPro; IPR031357; Stealth_CR3.
DR   Pfam; PF17101; Stealth_CR1; 1.
DR   Pfam; PF11380; Stealth_CR2; 1.
DR   Pfam; PF17102; Stealth_CR3; 1.
PE   3: Inferred from homology;
KW   Exopolysaccharide synthesis; Transferase.
FT   CHAIN           1..333
FT                   /note="Capsular polysaccharide phosphotransferase eps10H"
FT                   /id="PRO_0000235973"
SQ   SEQUENCE   333 AA;  38766 MW;  FD46CD1163E5DA87 CRC64;
     MTKVIDFVVT WVDGNDEKWR LKKAKYDGSI NTSKYSMNSE KAYREWGTFK YWFRGVEKFA
     PWVNKVYLVT DNQKPDWLNI DSDKLVLIDH KEIINNDFLP VFSANPIESN IHRIPGLSEH
     FVFFNDDMYL TAKVEPTDFF SEEGLPKYNT ALSPIIPERY GTGNFQINDM EIVNSHFTRN
     EILKNGKFFD PKQGLKNVVK SLLYKNSKFI CGFWESHLPY PLLKSTMELV WEKEKDILER
     TSASRFRNPS DTNVWLFKYW QIASGQYAIG NPKLGGLFTL DNAGPDFWSL LNSGKYQIMC
     INDGFNIQNE ELVMNNFINA LNSLLPEKSS FEL