AGO4B_ORYSJ
ID AGO4B_ORYSJ Reviewed; 911 AA.
AC Q0JF58; A0A0N7KIJ6;
DT 07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 03-OCT-2006, sequence version 1.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=Protein argonaute 4B;
DE Short=OsAGO4b;
GN Name=AGO4B; OrderedLocusNames=Os04g0151800, LOC_Os04g06770;
GN ORFNames=OsJ_13701;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18826656; DOI=10.1186/1471-2164-9-451;
RA Kapoor M., Arora R., Lama T., Nijhawan A., Khurana J.P., Tyagi A.K.,
RA Kapoor S.;
RT "Genome-wide identification, organization and phylogenetic analysis of
RT dicer-like, argonaute and RNA-dependent RNA polymerase gene families and
RT their expression analysis during reproductive development and stress in
RT rice.";
RL BMC Genomics 9:451-451(2008).
CC -!- FUNCTION: Probably involved in the RNA silencing pathway. May bind to
CC short RNAs such as microRNAs (miRNAs) or short interfering RNAs
CC (siRNAs), and represses the translation of mRNAs which are
CC complementary to them (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the argonaute family. Ago subfamily.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP008210; BAF14029.1; -; Genomic_DNA.
DR EMBL; AP014960; BAS87801.1; -; Genomic_DNA.
DR EMBL; CM000141; EEE60454.1; -; Genomic_DNA.
DR EMBL; AK122078; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015636673.1; XM_015781187.1.
DR AlphaFoldDB; Q0JF58; -.
DR SMR; Q0JF58; -.
DR STRING; 4530.OS04T0151800-02; -.
DR iPTMnet; Q0JF58; -.
DR PaxDb; Q0JF58; -.
DR PRIDE; Q0JF58; -.
DR EnsemblPlants; Os04t0151800-01; Os04t0151800-01; Os04g0151800.
DR EnsemblPlants; Os04t0151800-02; Os04t0151800-02; Os04g0151800.
DR GeneID; 4335025; -.
DR Gramene; Os04t0151800-01; Os04t0151800-01; Os04g0151800.
DR Gramene; Os04t0151800-02; Os04t0151800-02; Os04g0151800.
DR KEGG; osa:4335025; -.
DR eggNOG; KOG1041; Eukaryota.
DR HOGENOM; CLU_004544_2_0_1; -.
DR InParanoid; Q0JF58; -.
DR OMA; QVCHPRN; -.
DR OrthoDB; 159407at2759; -.
DR Proteomes; UP000000763; Chromosome 4.
DR Proteomes; UP000007752; Chromosome 4.
DR Proteomes; UP000059680; Chromosome 4.
DR ExpressionAtlas; Q0JF58; baseline and differential.
DR Genevisible; Q0JF58; OS.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0004521; F:endoribonuclease activity; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0035194; P:post-transcriptional gene silencing by RNA; IBA:GO_Central.
DR CDD; cd04657; Piwi_ago-like; 1.
DR Gene3D; 3.30.420.10; -; 1.
DR InterPro; IPR014811; ArgoL1.
DR InterPro; IPR032472; ArgoL2.
DR InterPro; IPR032473; Argonaute_Mid_dom.
DR InterPro; IPR032474; Argonaute_N.
DR InterPro; IPR003100; PAZ_dom.
DR InterPro; IPR036085; PAZ_dom_sf.
DR InterPro; IPR003165; Piwi.
DR InterPro; IPR045246; Piwi_ago-like.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR Pfam; PF08699; ArgoL1; 1.
DR Pfam; PF16488; ArgoL2; 1.
DR Pfam; PF16487; ArgoMid; 1.
DR Pfam; PF16486; ArgoN; 1.
DR Pfam; PF02170; PAZ; 1.
DR Pfam; PF02171; Piwi; 1.
DR SMART; SM01163; DUF1785; 1.
DR SMART; SM00950; Piwi; 1.
DR SUPFAM; SSF101690; SSF101690; 1.
DR SUPFAM; SSF53098; SSF53098; 1.
DR PROSITE; PS50821; PAZ; 1.
DR PROSITE; PS50822; PIWI; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; RNA-mediated gene silencing.
FT CHAIN 1..911
FT /note="Protein argonaute 4B"
FT /id="PRO_0000378432"
FT DOMAIN 275..396
FT /note="PAZ"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00142"
FT DOMAIN 565..872
FT /note="Piwi"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00150"
FT REGION 1..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 149..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 531
FT /note="D -> V (in Ref. 5; AK122078)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 911 AA; 101740 MW; 1502F495BC018520 CRC64;
MDAHDGEADE LPPPPPVPAN VVPIKADDVE SEVPANKPAK PKRFPMARPG LGRKGQPIQL
LANHYKVSVK SSEEYFFHYN VILKYEDDRP VDGKGVGRKV IDKLQQTYRS ELSSKDFAYD
GEKSLFTIGA LPQVTNEFTV VLEDVSTGKT AANGSPGGND SPGGSDRKRV RRPYQTKTFK
VELCFAAKIP MNAIAQAIKG QESENSQEAL RVLDIILRQH SAKQGCLLVR QSFFHNNPNN
FVDLGGGVMG CRGFHSSFRG TQSGLSLNID VSTTMIVKPG PVIDFLLANQ KVDHPDRIDW
QKAKRALKNL RIRTTPVNSE FKIIGLSDRN CNEQMFSLRQ RNGNNGDVDE VEVTVYDYFV
KNKGIELRYS GNLPCINVGK PKRPTYFPIE LCSLIPLQRY TKALSTLQRS SLVEKSRQKP
QERMSVLNDA LRHSNYDSDP MLRASGISIA QNFTQVEGRV LQPPKLKAGN GEDIFPRNGR
WNFNNKKLIQ TCSVDKWAVV NFSARCDVRN LIRDLIRNAS AKGIQMAEPF DVFEESPSLR
RAPVSRRVDD MFEQIKSKLP GAPKFLLCLL PERKNCEVYG PWKRKCLAEF GIVTQCLAPQ
RVNDQYLLNL LLKINAKLGG INSLLQIEAS PSIPLVSKTP TIILGMDVSH GQPGQSDRPS
IAAVVSSRQW PLISKYRASV HTQSPKLEMM SSLFKPRGTE DDGLIRESLI DFYTSSGKRK
PDHVIVFRDG VSESQFTQVI NIELDQIIEA CKFLDEKWSP KFTVIVAQKN HHTKFFQSGS
PDNVPPGTVV DKQVCHPRNY DFYMCAHAGM IGTTRPTHYH VLHDEIGFSP DDLQELVHSL
SYVYQRSTTA ISVVAPICYA HLAAAQVGTF LKFEDMSDAS SSQGGHTSVG SVPVPELPRL
HEKVRSSMFF C