ID   EPSD_BACSU              Reviewed;         381 AA.
AC   P71053; O08172; Q795I2;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Putative glycosyltransferase EpsD;
DE            EC=2.4.-.-;
GN   Name=epsD; Synonyms=yveN; OrderedLocusNames=BSU34340;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168trp;
RX   PubMed=8969506; DOI=10.1099/13500872-142-11-3089;
RA   Fabret C., Quentin Y., Chapal N., Guiseppi A., Haiech J., Denizot F.;
RT   "Integrated mapping and sequencing of a 115 kb DNA fragment from Bacillus
RT   subtilis: sequence analysis of a 21 kb segment containing the sigL locus.";
RL   Microbiology 142:3089-3096(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Denizot F.;
RL   Submitted (APR-1997) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [4]
RP   PROBABLE FUNCTION.
RX   PubMed=15175311; DOI=10.1128/jb.186.12.3970-3979.2004;
RA   Branda S.S., Gonzalez-Pastor J.E., Dervyn E., Ehrlich S.D., Losick R.,
RA   Kolter R.;
RT   "Genes involved in formation of structured multicellular communities by
RT   Bacillus subtilis.";
RL   J. Bacteriol. 186:3970-3979(2004).
RN   [5]
RP   PROBABLE FUNCTION, INDUCTION, AND NOMENCLATURE.
RX   PubMed=15661000; DOI=10.1111/j.1365-2958.2004.04440.x;
RA   Kearns D.B., Chu F., Branda S.S., Kolter R., Losick R.;
RT   "A master regulator for biofilm formation by Bacillus subtilis.";
RL   Mol. Microbiol. 55:739-749(2005).
CC   -!- FUNCTION: May be involved in the production of the exopolysaccharide
CC       (EPS) component of the extracellular matrix during biofilm formation.
CC       EPS is responsible for the adhesion of chains of cells into bundles.
CC       Required for biofilm maintenance.
CC   -!- INDUCTION: Repressed by SinR. {ECO:0000269|PubMed:15661000}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase group 1 family.
CC       Glycosyltransferase 4 subfamily. {ECO:0000305}.
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DR   EMBL; Z71928; CAA96471.1; -; Genomic_DNA.
DR   EMBL; Z94043; CAB08026.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB15439.1; -; Genomic_DNA.
DR   PIR; C70036; C70036.
DR   RefSeq; NP_391314.1; NC_000964.3.
DR   RefSeq; WP_003242735.1; NZ_JNCM01000033.1.
DR   AlphaFoldDB; P71053; -.
DR   SMR; P71053; -.
DR   STRING; 224308.BSU34340; -.
DR   CAZy; GT4; Glycosyltransferase Family 4.
DR   PaxDb; P71053; -.
DR   DNASU; 938611; -.
DR   EnsemblBacteria; CAB15439; CAB15439; BSU_34340.
DR   GeneID; 938611; -.
DR   KEGG; bsu:BSU34340; -.
DR   PATRIC; fig|224308.179.peg.3720; -.
DR   eggNOG; COG0438; Bacteria.
DR   InParanoid; P71053; -.
DR   OMA; INGCNEI; -.
DR   PhylomeDB; P71053; -.
DR   BioCyc; BSUB:BSU34340-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR028098; Glyco_trans_4-like_N.
DR   Pfam; PF13439; Glyco_transf_4; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
PE   2: Evidence at transcript level;
KW   Exopolysaccharide synthesis; Glycosyltransferase; Reference proteome;
KW   Transferase.
FT   CHAIN           1..381
FT                   /note="Putative glycosyltransferase EpsD"
FT                   /id="PRO_0000360791"
SQ   SEQUENCE   381 AA;  43571 MW;  4B17C113F2389853 CRC64;
     MTKKILFCAT VDYHFKAFHL PYFKWFKQMG WEVHVAANGQ TKLPYVDEKF SIPIRRSPFD
     PQNLAVYRQL KKVIDTYEYD IVHCHTPVGG VLARLAARQA RRHGTKVLYT AHGFHFCKGA
     PMKNWLLYYP VEKWLSAYTD CLITINEEDY IRAKGLQRPG GRTQKIHGIG VNTERFRPVS
     PIEQQRLREK HGFREDDFIL VYPAELNLNK NQKQLIEAAA LLKEKIPSLR LVFAGEGAME
     HTYQTLAEKL GASAHVCFYG FCSDIHELIQ LADVSVASSI REGLGMNVLE GMAAEQPAIA
     TDNRGHREII RDGENGFLIK IGDSAAFARR IEQLYHKPEL CRKLGQEGRK TALRFSEART
     VEEMADIYSA YMDMDTKEKS V