ID   EPSH_BACSU              Reviewed;         344 AA.
AC   P71057; O08176; Q795I6;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Putative glycosyltransferase EpsH;
DE            EC=2.4.-.-;
GN   Name=epsH; Synonyms=yveR; OrderedLocusNames=BSU34300;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168trp;
RX   PubMed=8969506; DOI=10.1099/13500872-142-11-3089;
RA   Fabret C., Quentin Y., Chapal N., Guiseppi A., Haiech J., Denizot F.;
RT   "Integrated mapping and sequencing of a 115 kb DNA fragment from Bacillus
RT   subtilis: sequence analysis of a 21 kb segment containing the sigL locus.";
RL   Microbiology 142:3089-3096(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Denizot F.;
RL   Submitted (APR-1997) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [4]
RP   FUNCTION.
RX   PubMed=15083514; DOI=10.1002/bit.20053;
RA   Ren D., Bedzyk L.A., Setlow P., Thomas S.M., Ye R.W., Wood T.K.;
RT   "Gene expression in Bacillus subtilis surface biofilms with and without
RT   sporulation and the importance of yveR for biofilm maintenance.";
RL   Biotechnol. Bioeng. 86:344-364(2004).
RN   [5]
RP   FUNCTION.
RX   PubMed=15175311; DOI=10.1128/jb.186.12.3970-3979.2004;
RA   Branda S.S., Gonzalez-Pastor J.E., Dervyn E., Ehrlich S.D., Losick R.,
RA   Kolter R.;
RT   "Genes involved in formation of structured multicellular communities by
RT   Bacillus subtilis.";
RL   J. Bacteriol. 186:3970-3979(2004).
RN   [6]
RP   FUNCTION, INDUCTION, AND NOMENCLATURE.
RX   PubMed=15661000; DOI=10.1111/j.1365-2958.2004.04440.x;
RA   Kearns D.B., Chu F., Branda S.S., Kolter R., Losick R.;
RT   "A master regulator for biofilm formation by Bacillus subtilis.";
RL   Mol. Microbiol. 55:739-749(2005).
CC   -!- FUNCTION: May be involved in the production of the exopolysaccharide
CC       (EPS) component of the extracellular matrix during biofilm formation.
CC       EPS is responsible for the adhesion of chains of cells into bundles.
CC       Required for biofilm maintenance. {ECO:0000269|PubMed:15083514,
CC       ECO:0000269|PubMed:15175311, ECO:0000269|PubMed:15661000}.
CC   -!- INDUCTION: Repressed by SinR. {ECO:0000269|PubMed:15661000}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. {ECO:0000305}.
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DR   EMBL; Z71928; CAA96475.1; -; Genomic_DNA.
DR   EMBL; Z94043; CAB08030.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB15435.1; -; Genomic_DNA.
DR   PIR; G70036; G70036.
DR   RefSeq; NP_391310.1; NC_000964.3.
DR   RefSeq; WP_003243644.1; NZ_JNCM01000033.1.
DR   AlphaFoldDB; P71057; -.
DR   SMR; P71057; -.
DR   STRING; 224308.BSU34300; -.
DR   CAZy; GT2; Glycosyltransferase Family 2.
DR   PaxDb; P71057; -.
DR   EnsemblBacteria; CAB15435; CAB15435; BSU_34300.
DR   GeneID; 938630; -.
DR   KEGG; bsu:BSU34300; -.
DR   PATRIC; fig|224308.179.peg.3716; -.
DR   eggNOG; COG1216; Bacteria.
DR   InParanoid; P71057; -.
DR   OMA; ICADPVF; -.
DR   PhylomeDB; P71057; -.
DR   BioCyc; BSUB:BSU34300-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR001173; Glyco_trans_2-like.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF00535; Glycos_transf_2; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   2: Evidence at transcript level;
KW   Exopolysaccharide synthesis; Glycosyltransferase; Reference proteome;
KW   Transferase.
FT   CHAIN           1..344
FT                   /note="Putative glycosyltransferase EpsH"
FT                   /id="PRO_0000360694"
SQ   SEQUENCE   344 AA;  39809 MW;  4A2B16582AF379BE CRC64;
     METPAVSLLV AVYNTETYIR TCLESLRNQT MDNIEIIIVN DGSADASPDI AEEYAKMDNR
     FKVIHQENQG LGAVRNKGIE AARGEFIAFI DSDDWIEPDY CEQMLRTAGD ETDLVICNYA
     AEFEDTGKTM DSDIAQTYQD QPKEHYIKAL FEGKVRGFSW NKLYRRSMIE AHRLSFPLRG
     ELEHVEDQFF SFRAHFFARS VSYVKTPLYH YRIHLSSIVQ RYQKKLFESG LALYETNAAF
     LQENNKLEEY RKELDTFIVL HSSICMLNEW KTSGSRRLFE KLRNVGVICA DPVFQESLSK
     TGTAPFDAKR SCLLLMAKYR MIPFVAMASA VYQRVIEYKM RNRG