ID   AGO7_ORYSJ              Reviewed;        1048 AA.
AC   Q75HC2; A0A0P0VZZ8; A4UTL6;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   07-JUL-2009, sequence version 2.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Protein argonaute 7;
DE            Short=OsAGO7;
DE   AltName: Full=Protein SHOOT ORGANIZATION 2;
DE   AltName: Full=Protein SHOOTLESS 4;
GN   Name=AGO7; Synonyms=SHL4, SHO2;
GN   OrderedLocusNames=Os03g0449200, LOC_Os03g33650; ORFNames=OSJNBa0034E08.23;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND FUNCTION.
RC   STRAIN=cv. Zhonghua 11;
RX   PubMed=17216479; DOI=10.1007/s00425-006-0472-0;
RA   Shi Z., Wang J., Wan X., Shen G., Wang X., Zhang J.;
RT   "Over-expression of rice OsAGO7 gene induces upward curling of the leaf
RT   blade that enhanced erect-leaf habit.";
RL   Planta 226:99-108(2007).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, DEVELOPMENTAL
RP   STAGE, AND DISRUPTION PHENOTYPE.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=17804793; DOI=10.1073/pnas.0704339104;
RA   Nagasaki H., Itoh J., Hayashi K., Hibara K., Satoh-Nagasawa N., Nosaka M.,
RA   Mukouhata M., Ashikari M., Kitano H., Matsuoka M., Nagato Y., Sato Y.;
RT   "The small interfering RNA production pathway is required for shoot
RT   meristem initiation in rice.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:14867-14871(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16109971; DOI=10.1101/gr.3869505;
RG   The rice chromosome 3 sequencing consortium;
RA   Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA   Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA   Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA   Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA   Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA   Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA   Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA   Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA   Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA   Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA   O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA   Jin W., Lee H.R., Jiang J., Jackson S.;
RT   "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT   and diverged grass species.";
RL   Genome Res. 15:1284-1291(2005).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [5]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [6]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [7]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=18826656; DOI=10.1186/1471-2164-9-451;
RA   Kapoor M., Arora R., Lama T., Nijhawan A., Khurana J.P., Tyagi A.K.,
RA   Kapoor S.;
RT   "Genome-wide identification, organization and phylogenetic analysis of
RT   dicer-like, argonaute and RNA-dependent RNA polymerase gene families and
RT   their expression analysis during reproductive development and stress in
RT   rice.";
RL   BMC Genomics 9:451-451(2008).
CC   -!- FUNCTION: Involved in the RNA silencing pathway. May bind to short RNAs
CC       such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and
CC       represses the translation of mRNAs which are complementary to them (By
CC       similarity). Regulates shoot apical meristem (SAM) initiation and
CC       maintenance and leaf polarization through the trans-acting siRNAS (ta-
CC       siRNAs) pathway which probably modulates the expression of the ARF2,
CC       ARF3, ARF4, ARF14 and ARF15 genes. {ECO:0000250,
CC       ECO:0000269|PubMed:17216479, ECO:0000269|PubMed:17804793}.
CC   -!- TISSUE SPECIFICITY: Expressed in the reproductive shoot apex.
CC       {ECO:0000269|PubMed:17804793}.
CC   -!- DISRUPTION PHENOTYPE: Lack of the shoot apical meristem (SAM) in the
CC       embryo, but formation of radicle and scutellum. In weak alleles,
CC       formation of an incomplete SAM and abnormal leaves production.
CC       {ECO:0000269|PubMed:17804793}.
CC   -!- SIMILARITY: Belongs to the argonaute family. Ago subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAS01930.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=ABF96954.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=BAF12387.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; EF486281; ABO93307.1; -; mRNA.
DR   EMBL; AB353924; BAF80152.1; -; mRNA.
DR   EMBL; AC135597; AAS01930.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; DP000009; ABF96954.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP008209; BAF12387.2; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014959; BAS84901.1; -; Genomic_DNA.
DR   RefSeq; XP_015629412.1; XM_015773926.1.
DR   AlphaFoldDB; Q75HC2; -.
DR   SMR; Q75HC2; -.
DR   STRING; 4530.OS03T0449200-00; -.
DR   PaxDb; Q75HC2; -.
DR   PRIDE; Q75HC2; -.
DR   EnsemblPlants; Os03t0449200-00; Os03t0449200-00; Os03g0449200.
DR   GeneID; 4333232; -.
DR   Gramene; Os03t0449200-00; Os03t0449200-00; Os03g0449200.
DR   KEGG; osa:4333232; -.
DR   eggNOG; KOG1041; Eukaryota.
DR   HOGENOM; CLU_004544_0_0_1; -.
DR   InParanoid; Q75HC2; -.
DR   OMA; MNWPSAN; -.
DR   OrthoDB; 220258at2759; -.
DR   Proteomes; UP000000763; Chromosome 3.
DR   Proteomes; UP000059680; Chromosome 3.
DR   Genevisible; Q75HC2; OS.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0004521; F:endoribonuclease activity; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0051607; P:defense response to virus; IEA:EnsemblPlants.
DR   GO; GO:0010599; P:lsiRNA processing; IEA:EnsemblPlants.
DR   GO; GO:0010492; P:maintenance of shoot apical meristem identity; IMP:UniProtKB.
DR   GO; GO:0035194; P:post-transcriptional gene silencing by RNA; IMP:UniProtKB.
DR   GO; GO:0040034; P:regulation of development, heterochronic; IEA:EnsemblPlants.
DR   GO; GO:0010267; P:ta-siRNA processing; IEA:EnsemblPlants.
DR   GO; GO:0010050; P:vegetative phase change; IEA:EnsemblPlants.
DR   CDD; cd04657; Piwi_ago-like; 1.
DR   Gene3D; 3.30.420.10; -; 1.
DR   InterPro; IPR014811; ArgoL1.
DR   InterPro; IPR032474; Argonaute_N.
DR   InterPro; IPR003100; PAZ_dom.
DR   InterPro; IPR036085; PAZ_dom_sf.
DR   InterPro; IPR003165; Piwi.
DR   InterPro; IPR045246; Piwi_ago-like.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   Pfam; PF08699; ArgoL1; 1.
DR   Pfam; PF16486; ArgoN; 1.
DR   Pfam; PF02170; PAZ; 1.
DR   Pfam; PF02171; Piwi; 1.
DR   SMART; SM01163; DUF1785; 1.
DR   SMART; SM00949; PAZ; 1.
DR   SMART; SM00950; Piwi; 1.
DR   SUPFAM; SSF101690; SSF101690; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   PROSITE; PS50821; PAZ; 1.
DR   PROSITE; PS50822; PIWI; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; RNA-mediated gene silencing.
FT   CHAIN           1..1048
FT                   /note="Protein argonaute 7"
FT                   /id="PRO_0000378433"
FT   DOMAIN          421..530
FT                   /note="PAZ"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00142"
FT   DOMAIN          709..1017
FT                   /note="Piwi"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00150"
FT   REGION          1..50
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          121..141
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1048 AA;  117498 MW;  B0E645D2F5E1C9A0 CRC64;
     MEGEREGVVA KNEDNAGGGG GGLGTGGNGG GGGGGSANGR RRWRGGGSSG YRQHPIIQAY
     PALLPLPING ATGHAHINGA VSLPLPLPPP VLLYLQPPPP PPLLPLLPKV AAATFYGKPP
     KAADAAPRGS MWKHRPSKKP PPHAITAALL PLPRDGKALQ EKIFFANERK TSEKEVNHVD
     THEKFTVAPL DNAIARRPDM GGVEGAEIPL SANHFLVQFD PGQKIFHYNV DISPRPSKET
     ARMIKKKLVE ENPSVLSGSQ PAFDGRKNLY SPVRFQEDRV EFFVSLPVAL ARCSVVKEDT
     GHMLDKQKLK TFKVNVRLVS KLCGEDLNKY LNEDKDGIPL PQDYLHALDV VLREGAMESS
     ILVGRSLYAR SMGEARDIGG GAVGLRGFFQ RLRPTKQGLA LNVDLSLSAF HESTGIISYL
     QKRCDFLKDL PQKKTRALAE EEHREVEKAL KNIRVFVCHR ETNQRYHVHS LTKETTENLK
     FRDRSGKDLM VVDYFKEHYN HDIQFRNLPC LQIGRSKPCY VPMELCVVCE GQKFLGKLSD
     EQTSKILKMG CERPSERKGI IKGVVKGAFH ARSDTYADQF SLQVSKHMTK LSGRVLLPPK
     LKLGSSGRIK DITPDRFDRQ WSFLDSHVAE GSKIKSWALI SFGGTPEQHF CITKFVNQLS
     NRCEQLGILL NKKTIISPIF ERIQLLNNVG ILEGKLKKIQ EAASGNLQLL ICVMERRHQG
     YADLKRIAET SIGVVTQCCL YSNLSKLTSQ FLTNLALKIN AKLGGCNIAL YSSFPCQIPR
     IFLSEEPVMF MGADVTHPHP LDDSSPSVVA VVASMNWPSA NKYISRMRSQ THRKEIIEQL
     DVMAGELLEE FLKEVGKLPS RIIFFRDGVS ETQFYKVLKE EMHAVRTTCS RYPGYKPLIT
     FIVVQKRHHT RLFHRERNGS SSHYSDQNIP PGTVVDTVIT HPREFDFYLC SHWGTKGTSR
     PTHYHVLWDE NNFRSDEVQQ LIHNLCYTFA RCTRPVSLVP PAYYAHLAAY RGRLYLERSD
     TTMYRVSPLQ TVPLPKLRDN VKRLMFYC