AGP17_ARATH
ID AGP17_ARATH Reviewed; 185 AA.
AC O22194;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 25-MAY-2022, entry version 104.
DE RecName: Full=Lysine-rich arabinogalactan protein 17;
DE Short=Lys-rich AGP 17;
DE Flags: Precursor;
GN Name=AGP17; Synonyms=RAT1; OrderedLocusNames=At2g23130;
GN ORFNames=F21P24.19, T20D16.24;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=11732052; DOI=10.1007/bf01280309;
RA Gilson P.R., Gaspar Y.M., Oxley D., Youl J.J., Bacic A.;
RT "NaAGP4 is an arabinogalactan protein whose expression is suppressed by
RT wounding and fungal infection in Nicotiana alata.";
RL Protoplasma 215:128-139(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12177459; DOI=10.1104/pp.003459;
RA Schultz C.J., Rumsewicz M.P., Johnson K.L., Jones B.J., Gaspar Y.M.,
RA Bacic A.;
RT "Using genomic resources to guide research directions. The arabinogalactan
RT protein gene family as a test case.";
RL Plant Physiol. 129:1448-1463(2002).
RN [7]
RP TISSUE SPECIFICITY.
RX PubMed=15286287; DOI=10.1104/pp.104.045542;
RA Gaspar Y.M., Nam J., Schultz C.J., Lee L.-Y., Gilson P.R., Gelvin S.B.,
RA Bacic A.;
RT "Characterization of the Arabidopsis lysine-rich arabinogalactan-protein
RT AtAGP17 mutant (rat1) that results in a decreased efficiency of
RT agrobacterium transformation.";
RL Plant Physiol. 135:2162-2171(2004).
RN [8]
RP TISSUE SPECIFICITY.
RX PubMed=15840645; DOI=10.1093/pcp/pci106;
RA Sun W., Xu J., Yang J., Kieliszewski M.J., Showalter A.M.;
RT "The lysine-rich arabinogalactan-protein subfamily in Arabidopsis: gene
RT expression, glycoprotein purification and biochemical characterization.";
RL Plant Cell Physiol. 46:975-984(2005).
CC -!- FUNCTION: Proteoglycan that seems to be implicated in diverse
CC developmental roles such as differentiation, cell-cell recognition,
CC embryogenesis and programmed cell death.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-
CC anchor {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=O22194-1; Sequence=Displayed;
CC -!- TISSUE SPECIFICITY: Predominantly expressed in open flowers. Also
CC expressed in leaves and stems, and at a lower level in roots.
CC {ECO:0000269|PubMed:15286287, ECO:0000269|PubMed:15840645}.
CC -!- PTM: O-glycosylated on the hydroxyproline residues. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the lysine-rich AGP family. {ECO:0000305}.
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DR EMBL; AF305939; AAG41963.1; -; mRNA.
DR EMBL; AC002391; AAB87117.1; -; Genomic_DNA.
DR EMBL; AC004401; AAM14931.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07416.1; -; Genomic_DNA.
DR EMBL; BT002926; AAO22741.1; -; mRNA.
DR EMBL; BT008601; AAP40426.1; -; mRNA.
DR EMBL; AY086875; AAM63921.1; -; mRNA.
DR PIR; T00519; T00519.
DR RefSeq; NP_179894.1; NM_127877.3. [O22194-1]
DR AlphaFoldDB; O22194; -.
DR STRING; 3702.AT2G23130.1; -.
DR PaxDb; O22194; -.
DR EnsemblPlants; AT2G23130.1; AT2G23130.1; AT2G23130. [O22194-1]
DR GeneID; 816845; -.
DR Gramene; AT2G23130.1; AT2G23130.1; AT2G23130. [O22194-1]
DR KEGG; ath:AT2G23130; -.
DR Araport; AT2G23130; -.
DR TAIR; locus:2045309; AT2G23130.
DR eggNOG; ENOG502S14T; Eukaryota.
DR OMA; PSKDTHI; -.
DR PRO; PR:O22194; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O22194; baseline and differential.
DR Genevisible; O22194; AT.
DR GO; GO:0031225; C:anchored component of membrane; TAS:TAIR.
DR GO; GO:0005886; C:plasma membrane; IDA:TAIR.
DR InterPro; IPR044981; AGP9/17/18.
DR PANTHER; PTHR37209; PTHR37209; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Cell membrane; Glycoprotein; GPI-anchor; Lipoprotein;
KW Membrane; Proteoglycan; Reference proteome; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..159
FT /note="Lysine-rich arabinogalactan protein 17"
FT /id="PRO_0000269031"
FT PROPEP 160..185
FT /note="Removed in mature form"
FT /evidence="ECO:0000255"
FT /id="PRO_0000269032"
FT REGION 25..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..48
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..94
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..146
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT LIPID 159
FT /note="GPI-anchor amidated serine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 185 AA; 18481 MW; 64A10CD28BF8EBAC CRC64;
MTRNILLTVT LICIVFITVG GQSPATAPIH SPSTSPHKPK PTSPAISPAA PTPESTEAPA
KTPVEAPVEA PPSPTPASTP QISPPAPSPE ADTPSAPEIA PSADVPAPAL TKHKKKTKKH
KTAPAPGPAS ELLSPPAPPG EAPGPGPSDA FSPAADDQSG AQRISVVIQM VGAAAIAWSL
LVLAF
