ID   AGP1_ASCSU              Reviewed;         591 AA.
AC   Q17045;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=GTP-binding protein AGP-1;
GN   Name=AGP-1;
OS   Ascaris suum (Pig roundworm) (Ascaris lumbricoides).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Ascarididae; Ascaris.
OX   NCBI_TaxID=6253;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Ovary;
RX   PubMed=8524289; DOI=10.1128/mcb.16.1.130;
RA   Huang Y.-J., Stoffel R., Tobler H., Mueller F.;
RT   "A newly formed telomere in Ascaris suum does not exert a telomere position
RT   effect on a nearby gene.";
RL   Mol. Cell. Biol. 16:130-134(1996).
CC   -!- DEVELOPMENTAL STAGE: Present at all developmental stages.
CC   -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC       superfamily. Classic translation factor GTPase family. GTPBP1
CC       subfamily. {ECO:0000255|PROSITE-ProRule:PRU01059}.
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DR   EMBL; L40995; AAA86432.1; -; mRNA.
DR   AlphaFoldDB; Q17045; -.
DR   SMR; Q17045; -.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   CDD; cd04165; GTPBP1_like; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR039263; GTPB1.
DR   InterPro; IPR035531; GTPBP1-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR   InterPro; IPR009000; Transl_B-barrel_sf.
DR   InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR   PANTHER; PTHR43721:SF9; PTHR43721:SF9; 1.
DR   Pfam; PF00009; GTP_EFTU; 1.
DR   SUPFAM; SSF50447; SSF50447; 1.
DR   SUPFAM; SSF50465; SSF50465; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51722; G_TR_2; 1.
PE   2: Evidence at transcript level;
KW   GTP-binding; Nucleotide-binding.
FT   CHAIN           1..591
FT                   /note="GTP-binding protein AGP-1"
FT                   /id="PRO_0000122472"
FT   DOMAIN          135..366
FT                   /note="tr-type G"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01059"
FT   REGION          7..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          144..151
FT                   /note="G1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01059"
FT   REGION          183..187
FT                   /note="G2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01059"
FT   REGION          229..232
FT                   /note="G3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01059"
FT   REGION          285..288
FT                   /note="G4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01059"
FT   REGION          343..345
FT                   /note="G5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01059"
FT   REGION          554..591
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         144..151
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255"
FT   BINDING         229..233
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255"
FT   BINDING         285..288
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   591 AA;  65421 MW;  D885AADC8D4E8AF0 CRC64;
     MNKAARAAAN FFAPDDDDAT SSGEGLTSND SFSRNFLVST DLSDEENRKA VEKYRSHIKS
     MLCCGEGEAI VELGVSIYDD TQKGLSKEEL QIAEERHKQL MNQSNISSSH LVTKRCGDLY
     TSFHLIRDSV DADDFIEVRV AVVGNVDAGK STLLGVLTHS ALDDGRGQAR RKLFRHKHEF
     ESGRTSSVGN DILGFSMDGQ IVNKPDVHSG NLDWVSICRD SAKVITFIDL AGHEKYLKTT
     IFGMTGHAPD YTMLMVGSNA GIIGMTKEHL SLALSLSVPV FVVVTKIDMC PDQVLAETLR
     NLDRLMKSPG VRKLPLPMRS MDDVVQRALH FAGGRLCPIF QVSNVVGTNL DLLKAFLNLI
     PLRRSLSLDS PAEFQVDDVY WVDGVGTVVS GTCLAGTIAL NDTMMIGPNA SGEFVPIPIK
     SIHRKRIACV EDSMWTDSII CIRKFNKKEV RKGMVLVSPL LKPRASLQFD AEVRVLHHPT
     TIARNYQAMV HVASIRQTAT IIQMTKEVLR TGDRDLVTFR FIRNPEYIRV GSRMVFREGR
     TKAVGTVIKV YPHMPAGATK QNRSKHAKQK DGHHSKQTYA SIEKERNASG H